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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2023

Holdings as of Sep 30, 2023, filed Nov 14, 2023. Long positions only; changes compare share counts with Q2 2023.

Institution overview
Positions
87
−1 vs. Q2 2023
Portfolio value
$2.97B
−$467.4M (−13.6%) vs. Q2 2023
Filed
Nov 14, 2023
SEC
Holdings of Perceptive Advisors LLC in Q3 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
FOLDAmicus Therapeutics, Inc.COM27,692,917$336.7M11.3%+30,000+0.1%AddedHistory
CERECerevel Therapeutics Holdings, Inc.COM10,088,385$220.2M7.4%00.0%UnchangedHistory
IMVTImmunovant, Inc.COM3,814,691$146.4M4.9%+1,290,908+51.1%AddedHistory
ACLXArcellx, Inc.COMMON STOCK3,965,978$142.3M4.8%−50,419−1.3%ReducedHistory
NUVLNuvalent, Inc.COM2,463,451$113.2M3.8%+268,630+12.2%AddedHistory
SLNOSoleno Therapeutics IncCOM3,074,542$90.7M3.1%+866,789+39.3%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$85.8M2.9%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM1,619,425$81.9M2.8%−321,250−16.6%ReducedHistory
INBXInhibrx Biosciences, Inc.COM4,256,104$78.1M2.6%+631,922+17.4%AddedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$75.8M2.5%00.0%UnchangedHistory
ARGXArgenx SESPONSORED ADR150,600$74.0M2.5%+81,600+118.3%AddedHistory
PCVXVaxcyte, Inc.COM1,342,751$68.5M2.3%−271,371−16.8%ReducedHistory
VRNAVerona Pharma plcSPONSORED ADS4,007,197$65.3M2.2%−389,919−8.9%ReducedHistory
CBAYCymaBay Therapeutics, Inc.COM4,043,191$60.3M2.0%+309,936+8.3%AddedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$55.6M1.9%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM11,962,938$54.4M1.8%−2,073,472−14.8%ReducedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$49.9M1.7%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM2,688,873$49.2M1.7%−2,185,046−44.8%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,748,933$46.1M1.6%00.0%UnchangedHistory
MDTMedtronic plcStock587,000$46.0M1.5%+120,000+25.7%AddedHistory
ROIVRoivant Sciences Ltd.SHS3,819,456$44.6M1.5%+687,720+22.0%AddedHistory
IRONDisc Medicine, Inc.COM895,641$42.1M1.4%+152,803+20.6%AddedHistory
IMTXImmatics N.V.SHS3,491,500$40.4M1.4%00.0%UnchangedHistory
APGEApogee Therapeutics, Inc.COM1,827,901$38.9M1.3%+1,827,901NewHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,263,732$37.6M1.3%−683,205−35.1%ReducedHistory
RVMDRevolution Medicines, Inc.COM1,321,795$36.6M1.2%+1,321,795NewHistory
SWTXSpringWorks Therapeutics, Inc.COM1,520,416$35.2M1.2%−17,015−1.1%ReducedHistory
AXSMAxsome Therapeutics, Inc.COM481,649$33.7M1.1%+210,156+77.4%AddedHistory
HRMYHarmony Biosciences Holdings, Inc.COM996,306$32.6M1.1%+104,936+11.8%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,920,658$31.9M1.1%−367,835−16.1%ReducedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,517,467$31.1M1.0%+349,104+29.9%AddedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$28.8M1.0%00.0%UnchangedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$28.8M1.0%00.0%UnchangedHistory
TNGXTango Therapeutics, Inc.COM2,418,968$27.2M0.9%+2,418,968NewHistory
ADMAAdma Biologics, Inc.COM6,984,319$25.0M0.8%−4,915,936−41.3%ReducedHistory
TMCITreace Medical Concepts, Inc.COM1,834,060$24.0M0.8%−383,190−17.3%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$23.0M0.8%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM2,309,470$22.5M0.8%−350,000−13.2%ReducedHistory
SRPTSarepta Therapeutics, Inc.COM182,720$22.1M0.7%+101,646+125.4%AddedHistory
MIRMMirum Pharmaceuticals, Inc.COM672,042$21.2M0.7%+70,476+11.7%AddedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,432,089$21.2M0.7%+379,221+18.5%AddedHistory
XENEXenon Pharmaceuticals Inc.COM617,500$21.1M0.7%−605,877−49.5%ReducedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$19.6M0.7%00.0%UnchangedHistory
BHVNBiohaven Ltd.COM751,820$19.6M0.7%+431,000+134.3%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM124,637$18.2M0.6%−178,350−58.9%ReducedHistory
NBIXNeurocrine Biosciences IncStock159,242$17.9M0.6%+59,192+59.2%AddedHistory
PTGXProtagonist Therapeutics, IncCOM1,054,273$17.6M0.6%−415,488−28.3%ReducedHistory
RYZBRayzeBio, Inc.COM776,805$17.2M0.6%+776,805NewHistory
CABACabaletta Bio, Inc.COM1,132,491$17.2M0.6%−412,509−26.7%ReducedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$16.3M0.5%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,189,462$16.3M0.5%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM1,011,205$15.5M0.5%−765,181−43.1%ReducedHistory
AORTArtivion, Inc.COM931,352$14.1M0.5%00.0%UnchangedHistory
ESTAEstablishment Labs Holdings Inc.COM277,683$13.6M0.5%−147,241−34.7%ReducedHistory
EOLSEvolus, Inc.COM1,485,801$13.6M0.5%+1,485,801NewHistory
TCMDTactile Systems Technology IncCOM707,159$9.94M0.3%+104,782+17.4%AddedHistory
BMEABiomea Fusion, Inc.COM716,441$9.86M0.3%00.0%UnchangedHistory
LONALeonaBio, Inc.COM4,797,278$9.69M0.3%00.0%UnchangedHistory
NTRANatera, Inc.COM218,178$9.65M0.3%−187,091−46.2%ReducedHistory
ZYMEZymeworks Inc.COM1,446,123$9.17M0.3%−970,109−40.1%ReducedHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$8.81M0.3%00.0%UnchangedHistory
RYTMRhythm Pharmaceuticals, Inc.COM380,828$8.73M0.3%+380,828NewHistory
CMAXCareMax, Inc.COM CL A3,823,557$8.11M0.3%+6,153+0.2%AddedHistory
PRTAProthena Corp Public Ltd CoSHS165,615$7.99M0.3%−19,000−10.3%ReducedHistory
OMOutset Medical, Inc.COM661,977$7.20M0.2%−240,383−26.6%ReducedHistory
FUSNFusion Pharmaceuticals Inc.COM2,751,395$7.15M0.2%00.0%UnchangedHistory
LABPLandos Biopharma, Inc.COM NEW1,486,991$5.77M0.2%00.0%UnchangedHistory
TERNTerns Pharmaceuticals, Inc.COM1,075,000$5.41M0.2%+1,075,000NewHistory
TYRATyra Biosciences, Inc.COM360,000$4.96M0.2%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$4.86M0.2%−504,734−47.6%ReducedHistory
AXGNAxogen, Inc.COM875,898$4.38M0.1%−588,924−40.2%ReducedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$4.21M0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$3.86M0.1%00.0%UnchangedHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.58M0.1%00.0%UnchangedHistory
TVTXTravere Therapeutics, Inc.COM400,000$3.58M0.1%+309,252+340.8%AddedHistory
KRONKronos Bio, Inc.COM1,752,745$2.28M0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM3,265,359$2.16M0.1%+3,265,359NewHistory
SLRNACELYRIN, Inc.COM200,000$2.03M0.1%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW81,116$993.7K<0.1%+81,116NewHistory
VBIVVBI Vaccines Inc/BCCOM1,381,355$925.5K<0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM2,363,214$900.4K<0.1%00.0%UnchangedHistory
VERUVeru Inc.COM1,089,878$783.6K<0.1%+1,000,000+1,112.6%AddedHistory
CYPHCypherpunk Technologies Inc.COM NEW44,971$62.1K<0.1%−541,762−92.3%ReducedHistory
MOTSMotus GI Holdings, Inc.COM NEW90,027$40.5K<0.1%00.0%UnchangedHistory
CareMax, Inc.14171W111*W EXP 06/08/20260,000$11.3K<0.1%00.0%Unchanged–
EQRx, Inc.26886C115*W EXP 12/17/202250,000$10.0K<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$6.67K<0.1%00.0%Unchanged–

Options (10)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2023
SecurityClassPutsCalls
AKROAkero Therapeutics, Inc.COM–$5.46M
NVAXNovavax IncCOM NEW$3.77M–
SRPTSarepta Therapeutics, Inc.COM–$3.13M
PNTPOINT Biopharma Global Inc.COM$2.63M–
ARQTArcutis Biotherapeutics, Inc.COM$2.62M–
EYPTEyePoint, Inc.COM NEW$2.51M–
ETNB89bio, Inc.COM–$1.62M
ACRSAclaris Therapeutics, Inc.COM$1.45M–
VKTXViking Therapeutics, Inc.COM–$240.0K
APLSApellis Pharmaceuticals, Inc.COM$72.5K–

Sold out since Q2 2023 (10)

Positions held at the end of Q2 2023 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2023
SecurityClassShares in Q2 2023Value in Q2 2023% of portfolio in Q2 2023History
APLSApellis Pharmaceuticals, Inc.COM812,037$74.0M2.1%History
RETAReata Pharmaceuticals IncCL A670,206$68.3M2.0%History
VIRVir Biotechnology, Inc.COM1,958,264$48.0M1.4%History
ILMNIllumina, Inc.COM145,000$27.2M0.8%History
MRTXMirati Therapeutics, Inc.COM719,103$26.0M0.8%History
BMRNBiomarin Pharmaceutical IncCOM263,207$22.8M0.7%History
ITCIIntra-Cellular Therapies, Inc.COM245,800$15.6M0.5%History
VKTXViking Therapeutics, Inc.COM441,147$7.15M0.2%History
ISEEIVERIC bio, Inc.COM168,000$6.61M0.2%History
QTRXQuanterix CorpCOM130,000$2.93M0.1%History