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Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q3 2023

Holdings as of Sep 30, 2023, filed Nov 14, 2023. Long positions only; changes compare share counts with Q2 2023.

Institution overview
Positions
87
−1 vs. Q2 2023
Portfolio value
$2.97B
−$467.4M (−13.6%) vs. Q2 2023
Filed
Nov 14, 2023
SEC
Holdings of Perceptive Advisors LLC in Q3 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$6.67K<0.1%00.0%Unchanged–
EQRx, Inc.26886C115*W EXP 12/17/202250,000$10.0K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$11.3K<0.1%00.0%Unchanged–
MOTSMotus GI Holdings, Inc.COM NEW90,027$40.5K<0.1%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM NEW44,971$62.1K<0.1%−541,762−92.3%ReducedHistory
VERUVeru Inc.COM1,089,878$783.6K<0.1%+1,000,000+1,112.6%AddedHistory
OMICSingular Genomics Systems, Inc.COM2,363,214$900.4K<0.1%00.0%UnchangedHistory
VBIVVBI Vaccines Inc/BCCOM1,381,355$925.5K<0.1%00.0%UnchangedHistory
SYRESpyre Therapeutics, Inc.COM NEW81,116$993.7K<0.1%+81,116NewHistory
SLRNACELYRIN, Inc.COM200,000$2.03M0.1%00.0%UnchangedHistory
FBRXForte Biosciences, Inc.COM3,265,359$2.16M0.1%+3,265,359NewHistory
KRONKronos Bio, Inc.COM1,752,745$2.28M0.1%00.0%UnchangedHistory
TVTXTravere Therapeutics, Inc.COM400,000$3.58M0.1%+309,252+340.8%AddedHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.58M0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$3.86M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$4.21M0.1%00.0%UnchangedHistory
AXGNAxogen, Inc.COM875,898$4.38M0.1%−588,924−40.2%ReducedHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$4.86M0.2%−504,734−47.6%ReducedHistory
TYRATyra Biosciences, Inc.COM360,000$4.96M0.2%00.0%UnchangedHistory
TERNTerns Pharmaceuticals, Inc.COM1,075,000$5.41M0.2%+1,075,000NewHistory
LABPLandos Biopharma, Inc.COM NEW1,486,991$5.77M0.2%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM2,751,395$7.15M0.2%00.0%UnchangedHistory
OMOutset Medical, Inc.COM661,977$7.20M0.2%−240,383−26.6%ReducedHistory
PRTAProthena Corp Public Ltd CoSHS165,615$7.99M0.3%−19,000−10.3%ReducedHistory
CMAXCareMax, Inc.COM CL A3,823,557$8.11M0.3%+6,153+0.2%AddedHistory
RYTMRhythm Pharmaceuticals, Inc.COM380,828$8.73M0.3%+380,828NewHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$8.81M0.3%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM1,446,123$9.17M0.3%−970,109−40.1%ReducedHistory
NTRANatera, Inc.COM218,178$9.65M0.3%−187,091−46.2%ReducedHistory
LONALeonaBio, Inc.COM4,797,278$9.69M0.3%00.0%UnchangedHistory
BMEABiomea Fusion, Inc.COM716,441$9.86M0.3%00.0%UnchangedHistory
TCMDTactile Systems Technology IncCOM707,159$9.94M0.3%+104,782+17.4%AddedHistory
EOLSEvolus, Inc.COM1,485,801$13.6M0.5%+1,485,801NewHistory
ESTAEstablishment Labs Holdings Inc.COM277,683$13.6M0.5%−147,241−34.7%ReducedHistory
AORTArtivion, Inc.COM931,352$14.1M0.5%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM1,011,205$15.5M0.5%−765,181−43.1%ReducedHistory
ATXSAstria Therapeutics, Inc.COM2,189,462$16.3M0.5%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$16.3M0.5%00.0%UnchangedHistory
CABACabaletta Bio, Inc.COM1,132,491$17.2M0.6%−412,509−26.7%ReducedHistory
RYZBRayzeBio, Inc.COM776,805$17.2M0.6%+776,805NewHistory
PTGXProtagonist Therapeutics, IncCOM1,054,273$17.6M0.6%−415,488−28.3%ReducedHistory
NBIXNeurocrine Biosciences IncStock159,242$17.9M0.6%+59,192+59.2%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM124,637$18.2M0.6%−178,350−58.9%ReducedHistory
BHVNBiohaven Ltd.COM751,820$19.6M0.7%+431,000+134.3%AddedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$19.6M0.7%00.0%UnchangedHistory
XENEXenon Pharmaceuticals Inc.COM617,500$21.1M0.7%−605,877−49.5%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,432,089$21.2M0.7%+379,221+18.5%AddedHistory
MIRMMirum Pharmaceuticals, Inc.COM672,042$21.2M0.7%+70,476+11.7%AddedHistory
SRPTSarepta Therapeutics, Inc.COM182,720$22.1M0.7%+101,646+125.4%AddedHistory
COGTCogent Biosciences, Inc.COM2,309,470$22.5M0.8%−350,000−13.2%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$23.0M0.8%00.0%UnchangedHistory
TMCITreace Medical Concepts, Inc.COM1,834,060$24.0M0.8%−383,190−17.3%ReducedHistory
ADMAAdma Biologics, Inc.COM6,984,319$25.0M0.8%−4,915,936−41.3%ReducedHistory
TNGXTango Therapeutics, Inc.COM2,418,968$27.2M0.9%+2,418,968NewHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$28.8M1.0%00.0%UnchangedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$28.8M1.0%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,517,467$31.1M1.0%+349,104+29.9%AddedHistory
RAPTRAPT Therapeutics, Inc.COM1,920,658$31.9M1.1%−367,835−16.1%ReducedHistory
HRMYHarmony Biosciences Holdings, Inc.COM996,306$32.6M1.1%+104,936+11.8%AddedHistory
AXSMAxsome Therapeutics, Inc.COM481,649$33.7M1.1%+210,156+77.4%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,520,416$35.2M1.2%−17,015−1.1%ReducedHistory
RVMDRevolution Medicines, Inc.COM1,321,795$36.6M1.2%+1,321,795NewHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,263,732$37.6M1.3%−683,205−35.1%ReducedHistory
APGEApogee Therapeutics, Inc.COM1,827,901$38.9M1.3%+1,827,901NewHistory
IMTXImmatics N.V.SHS3,491,500$40.4M1.4%00.0%UnchangedHistory
IRONDisc Medicine, Inc.COM895,641$42.1M1.4%+152,803+20.6%AddedHistory
ROIVRoivant Sciences Ltd.SHS3,819,456$44.6M1.5%+687,720+22.0%AddedHistory
MDTMedtronic plcStock587,000$46.0M1.5%+120,000+25.7%AddedHistory
BBIOBridgeBio Pharma, Inc.COM1,748,933$46.1M1.6%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM2,688,873$49.2M1.7%−2,185,046−44.8%ReducedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$49.9M1.7%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM11,962,938$54.4M1.8%−2,073,472−14.8%ReducedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$55.6M1.9%00.0%UnchangedHistory
CBAYCymaBay Therapeutics, Inc.COM4,043,191$60.3M2.0%+309,936+8.3%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS4,007,197$65.3M2.2%−389,919−8.9%ReducedHistory
PCVXVaxcyte, Inc.COM1,342,751$68.5M2.3%−271,371−16.8%ReducedHistory
ARGXArgenx SESPONSORED ADR150,600$74.0M2.5%+81,600+118.3%AddedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$75.8M2.5%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM4,256,104$78.1M2.6%+631,922+17.4%AddedHistory
AKROAkero Therapeutics, Inc.COM1,619,425$81.9M2.8%−321,250−16.6%ReducedHistory
LIANYLianBioSPONSORED ADS57,558,451$85.8M2.9%00.0%UnchangedHistory
SLNOSoleno Therapeutics IncCOM3,074,542$90.7M3.1%+866,789+39.3%AddedHistory
NUVLNuvalent, Inc.COM2,463,451$113.2M3.8%+268,630+12.2%AddedHistory
ACLXArcellx, Inc.COMMON STOCK3,965,978$142.3M4.8%−50,419−1.3%ReducedHistory
IMVTImmunovant, Inc.COM3,814,691$146.4M4.9%+1,290,908+51.1%AddedHistory
CERECerevel Therapeutics Holdings, Inc.COM10,088,385$220.2M7.4%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM27,692,917$336.7M11.3%+30,000+0.1%AddedHistory

Options (10)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q3 2023
SecurityClassPutsCalls
AKROAkero Therapeutics, Inc.COM–$5.46M
NVAXNovavax IncCOM NEW$3.77M–
SRPTSarepta Therapeutics, Inc.COM–$3.13M
PNTPOINT Biopharma Global Inc.COM$2.63M–
ARQTArcutis Biotherapeutics, Inc.COM$2.62M–
EYPTEyePoint, Inc.COM NEW$2.51M–
ETNB89bio, Inc.COM–$1.62M
ACRSAclaris Therapeutics, Inc.COM$1.45M–
VKTXViking Therapeutics, Inc.COM–$240.0K
APLSApellis Pharmaceuticals, Inc.COM$72.5K–

Sold out since Q2 2023 (10)

Positions held at the end of Q2 2023 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q2 2023
SecurityClassShares in Q2 2023Value in Q2 2023% of portfolio in Q2 2023History
APLSApellis Pharmaceuticals, Inc.COM812,037$74.0M2.1%History
RETAReata Pharmaceuticals IncCL A670,206$68.3M2.0%History
VIRVir Biotechnology, Inc.COM1,958,264$48.0M1.4%History
ILMNIllumina, Inc.COM145,000$27.2M0.8%History
MRTXMirati Therapeutics, Inc.COM719,103$26.0M0.8%History
BMRNBiomarin Pharmaceutical IncCOM263,207$22.8M0.7%History
ITCIIntra-Cellular Therapies, Inc.COM245,800$15.6M0.5%History
VKTXViking Therapeutics, Inc.COM441,147$7.15M0.2%History
ISEEIVERIC bio, Inc.COM168,000$6.61M0.2%History
QTRXQuanterix CorpCOM130,000$2.93M0.1%History