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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q2 2023

Holdings as of Jun 30, 2023, filed Aug 24, 2023. Long positions only; changes compare share counts with Q1 2023.

Institution overview
Positions
88
−10 vs. Q1 2023
Portfolio value
$3.44B
+$62.4M (+1.8%) vs. Q1 2023
Filed
Aug 24, 2023
AmendedSEC
Holdings of Perceptive Advisors LLC in Q2 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
FOLDAmicus Therapeutics, Inc.COM27,662,917$347.4M10.1%00.0%UnchangedHistory
CERECerevel Therapeutics Holdings, Inc.COM10,088,385$320.7M9.3%+3,576,658+54.9%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$131.2M3.8%00.0%UnchangedHistory
ACLXArcellx, Inc.COMMON STOCK4,016,397$127.0M3.7%+174,658+4.5%AddedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM4,873,919$105.1M3.1%−1,160,725−19.2%ReducedHistory
IOVAIovance Biotherapeutics, Inc.COM14,036,410$98.8M2.9%−1,303,325−8.5%ReducedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$95.2M2.8%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM3,624,182$94.1M2.7%+8,799+0.2%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS4,397,116$93.0M2.7%+1,663,326+60.8%AddedHistory
NUVLNuvalent, Inc.COM2,194,821$92.6M2.7%−105,227−4.6%ReducedHistory
AKROAkero Therapeutics, Inc.COM1,940,675$90.6M2.6%+1,417,150+270.7%AddedHistory
PCVXVaxcyte, Inc.COM1,614,122$80.6M2.3%+444,122+38.0%AddedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$76.1M2.2%+4,367,826+62.7%AddedHistory
APLSApellis Pharmaceuticals, Inc.COM812,037$74.0M2.1%+256,693+46.2%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM302,987$70.0M2.0%−347,575−53.4%ReducedHistory
RETAReata Pharmaceuticals IncCL A670,206$68.3M2.0%−1,499,070−69.1%ReducedHistory
TMCITreace Medical Concepts, Inc.COM2,217,250$56.7M1.6%−225,000−9.2%ReducedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$52.4M1.5%+3,610,832+39.5%AddedHistory
VIRVir Biotechnology, Inc.COM1,958,264$48.0M1.4%+1,816,070+1,277.2%AddedHistory
IMVTImmunovant, Inc.COM2,523,783$47.9M1.4%+1,231,925+95.4%AddedHistory
XENEXenon Pharmaceuticals Inc.COM1,223,377$47.1M1.4%−608,797−33.2%ReducedHistory
ADMAAdma Biologics, Inc.COM11,900,255$43.9M1.3%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM2,288,493$42.8M1.2%−3,115−0.1%ReducedHistory
VRDNViridian Therapeutics, Inc.COM1,776,386$42.3M1.2%+40,000+2.3%AddedHistory
MDTMedtronic plcStock467,000$41.1M1.2%+467,000NewHistory
CBAYCymaBay Therapeutics, Inc.COM3,733,255$40.9M1.2%−170,000−4.4%ReducedHistory
PTGXProtagonist Therapeutics, IncCOM1,469,761$40.6M1.2%+504,609+52.3%AddedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,537,431$40.3M1.2%−541,921−26.1%ReducedHistory
IMTXImmatics N.V.SHS3,491,500$40.3M1.2%00.0%UnchangedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$39.0M1.1%00.0%UnchangedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$35.3M1.0%00.0%UnchangedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,946,937$35.1M1.0%−1,607,950−45.2%ReducedHistory
IRONDisc Medicine, Inc.COM742,838$33.0M1.0%+742,838NewHistory
ROIVRoivant Sciences Ltd.SHS3,131,736$31.6M0.9%+439,600+16.3%AddedHistory
COGTCogent Biosciences, Inc.COM2,659,470$31.5M0.9%+377,146+16.5%AddedHistory
HRMYHarmony Biosciences Holdings, Inc.COM891,370$31.4M0.9%+791,370+791.4%AddedHistory
BBIOBridgeBio Pharma, Inc.COM1,748,933$30.1M0.9%−158,100−8.3%ReducedHistory
ESTAEstablishment Labs Holdings Inc.COM424,924$29.2M0.8%−42,933−9.2%ReducedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$29.1M0.8%00.0%UnchangedHistory
ILMNIllumina, Inc.COM145,000$27.2M0.8%+145,000NewHistory
ARGXArgenx SESPONSORED ADR69,000$26.9M0.8%+69,000NewHistory
MRTXMirati Therapeutics, Inc.COM719,103$26.0M0.8%−855,031−54.3%ReducedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$24.4M0.7%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$23.4M0.7%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,168,363$23.2M0.7%+300,631+34.6%AddedHistory
BMRNBiomarin Pharmaceutical IncCOM263,207$22.8M0.7%−409,853−60.9%ReducedHistory
ZYMEZymeworks Inc.COM2,416,232$20.9M0.6%−962,266−28.5%ReducedHistory
CABACabaletta Bio, Inc.COM1,545,000$19.9M0.6%+820,223+113.2%AddedHistory
OMOutset Medical, Inc.COM902,360$19.7M0.6%−187,067−17.2%ReducedHistory
NTRANatera, Inc.COM405,269$19.7M0.6%−301,945−42.7%ReducedHistory
AXSMAxsome Therapeutics, Inc.COM271,493$19.5M0.6%+271,493NewHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$18.3M0.5%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,189,462$18.2M0.5%00.0%UnchangedHistory
AORTArtivion, Inc.COM931,352$16.0M0.5%−154,508−14.2%ReducedHistory
BMEABiomea Fusion, Inc.COM716,441$15.7M0.5%+391,441+120.4%AddedHistory
ITCIIntra-Cellular Therapies, Inc.COM245,800$15.6M0.5%+245,800NewHistory
MIRMMirum Pharmaceuticals, Inc.COM601,566$15.6M0.5%00.0%UnchangedHistory
TCMDTactile Systems Technology IncCOM602,377$15.0M0.4%−37,500−5.9%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,052,868$14.4M0.4%−225,358−9.9%ReducedHistory
LONALeonaBio, Inc.COM4,797,278$14.2M0.4%00.0%UnchangedHistory
AXGNAxogen, Inc.COM1,464,822$13.4M0.4%+55,031+3.9%AddedHistory
FUSNFusion Pharmaceuticals Inc.COM2,751,395$12.8M0.4%−8,541−0.3%ReducedHistory
PRTAProthena Corp Public Ltd CoSHS184,615$12.6M0.4%−53,031−22.3%ReducedHistory
CMAXCareMax, Inc.COM CL A3,817,404$11.9M0.3%+241,364+6.7%AddedHistory
SLNOSoleno Therapeutics IncCOM2,207,753$9.47M0.3%+2,207,753NewHistory
NBIXNeurocrine Biosciences IncStock100,050$9.43M0.3%00.0%UnchangedHistory
SRPTSarepta Therapeutics, Inc.COM81,074$9.28M0.3%−179,784−68.9%ReducedHistory
BHVNBiohaven Ltd.COM320,820$7.67M0.2%+320,820NewHistory
VKTXViking Therapeutics, Inc.COM441,147$7.15M0.2%−430,600−49.4%ReducedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$6.88M0.2%−1,000,000−22.0%ReducedHistory
ISEEIVERIC bio, Inc.COM168,000$6.61M0.2%−332,000−66.4%ReducedHistory
LABPLandos Biopharma, Inc.COM NEW1,486,991$6.26M0.2%+1,486,991NewHistory
TYRATyra Biosciences, Inc.COM360,000$6.13M0.2%−134,403−27.2%ReducedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$5.37M0.2%00.0%UnchangedHistory
VBIVVBI Vaccines Inc/BCCOM1,381,355$4.54M0.1%−363,145−20.8%ReducedConverted for a 1-for-30 splitHistory
SLRNACELYRIN, Inc.COM200,000$4.18M0.1%+200,000NewHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.46M0.1%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM1,752,745$3.01M0.1%00.0%UnchangedHistory
QTRXQuanterix CorpCOM130,000$2.93M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$2.41M0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM2,363,214$1.96M0.1%−919,061−28.0%ReducedHistory
CYPHCypherpunk Technologies Inc.COM NEW586,733$1.84M0.1%−85,917−12.8%ReducedConverted for a 1-for-10 splitHistory
TVTXTravere Therapeutics, Inc.COM90,748$1.39M<0.1%00.0%UnchangedHistory
VERUVeru Inc.COM89,878$107.0K<0.1%−4,208,334−97.9%ReducedHistory
MOTSMotus GI Holdings, Inc.COM NEW90,027$60.3K<0.1%00.0%UnchangedHistory
EQRx, Inc.26886C115*W EXP 12/17/202250,000$42.5K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$23.4K<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$10.0K<0.1%00.0%Unchanged–

Options (7)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q2 2023
SecurityClassPutsCalls
TERNTerns Pharmaceuticals, Inc.COM$9.41M–
ARQTArcutis Biotherapeutics, Inc.COM$1.42M–
MRTXMirati Therapeutics, Inc.COM–$690.0K
VRNAVerona Pharma plcSPONSORED ADS–$675.0K
PNTPOINT Biopharma Global Inc.COM$675.0K–
State Street SPDR S&P Biotech ETF78464A870ETF$137.5K–
BTAIQBioXcel Therapeutics, Inc.COM–$11.0K

Sold out since Q1 2023 (20)

Positions held at the end of Q1 2023 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q1 2023
SecurityClassShares in Q1 2023Value in Q1 2023% of portfolio in Q1 2023History
RXDXPrometheus Biosciences, Inc.COM1,272,694$136.6M4.0%History
SNYSanofiSPONSORED ADR768,101$41.8M1.2%History
Bellus Health Inc New07987C204COM NEW4,952,538$35.7M1.1%–
TERNTerns Pharmaceuticals, Inc.COM1,350,000$16.0M0.5%History
Rain Oncology Inc.75082Q105COM1,648,215$14.4M0.4%–
ISRGIntuitive Surgical IncCOM NEW50,000$12.8M0.4%History
CTKBCytek Biosciences, Inc.COM1,289,534$11.9M0.4%History
LRMRLarimar Therapeutics, Inc.COM2,280,709$10.3M0.3%History
MORFMorphic Holding, Inc.COM256,737$9.66M0.3%History
BLPHBellerophon Therapeutics, Inc.COM NEW930,000$7.34M0.2%History
HLVXHilleVax, Inc.COM406,024$6.71M0.2%History
AVDLAvadel Pharmaceuticals PLCSPONSORED ADR590,000$5.40M0.2%History
LABPLandos Biopharma, Inc.COM14,869,915$4.43M0.1%History
ADCTADC Therapeutics SASHS1,495,805$2.92M0.1%History
CELLBruker Cellular Analysis, Inc.COM2,506,442$2.91M0.1%History
DRIODarioHealth Corp.COM NEW313,869$1.29M<0.1%History
CLOVClover Health Investments, Corp.COM CL A1,500,000$1.27M<0.1%History
ATNXAthenex, Inc.COM NEW776,623$1.03M<0.1%History
TARAProtara Therapeutics, Inc.COM STK290,051$907.9K<0.1%History
PEARPear Therapeutics, Inc.CLASS A COM900,548$229.6K<0.1%History