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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q1 2023

Holdings as of Mar 31, 2023, filed May 16, 2023. Long positions only; changes compare share counts with Q4 2022.

Institution overview
Positions
98
+4 vs. Q4 2022
Portfolio value
$3.38B
−$90.3M (−2.6%) vs. Q4 2022
Filed
May 16, 2023
AmendedSEC
Holdings of Perceptive Advisors LLC in Q1 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
FOLDAmicus Therapeutics, Inc.COM27,662,917$306.8M9.1%+20,000+0.1%AddedHistory
RETAReata Pharmaceuticals IncCL A2,169,276$197.2M5.8%+2,169,276NewHistory
AMLXAmylyx Pharmaceuticals, Inc.COM6,034,644$177.1M5.2%−53,689−0.9%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM6,511,727$158.9M4.7%00.0%UnchangedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM650,562$157.6M4.7%−81,370−11.1%ReducedHistory
RXDXPrometheus Biosciences, Inc.COM1,272,694$136.6M4.0%+60,000+4.9%AddedHistory
ACLXArcellx, Inc.COMMON STOCK3,841,739$118.4M3.5%+1,243,434+47.9%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$112.8M3.3%00.0%UnchangedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$112.7M3.3%00.0%UnchangedHistory
IOVAIovance Biotherapeutics, Inc.COM15,339,735$93.7M2.8%+5,367,955+53.8%AddedHistory
INBXInhibrx Biosciences, Inc.COM3,615,383$68.2M2.0%+301,600+9.1%AddedHistory
XENEXenon Pharmaceuticals Inc.COM1,832,174$65.6M1.9%−89,099−4.6%ReducedHistory
BMRNBiomarin Pharmaceutical IncCOM673,060$65.4M1.9%+166,579+32.9%AddedHistory
TMCITreace Medical Concepts, Inc.COM2,442,250$61.5M1.8%+495,847+25.5%AddedHistory
NUVLNuvalent, Inc.COM2,300,048$60.0M1.8%+45,041+2.0%AddedHistory
MRTXMirati Therapeutics, Inc.COM1,574,134$58.5M1.7%−617,291−28.2%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM3,554,887$57.1M1.7%−484,389−12.0%ReducedHistory
VRNAVerona Pharma plcSPONSORED ADS2,733,790$54.9M1.6%−2,146,929−44.0%ReducedHistory
SWTXSpringWorks Therapeutics, Inc.COM2,079,352$53.5M1.6%−538,339−20.6%ReducedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,278,226$44.6M1.3%+2,278,226NewHistory
VRDNViridian Therapeutics, Inc.COM1,736,386$44.2M1.3%+515,811+42.3%AddedHistory
PCVXVaxcyte, Inc.COM1,170,000$43.9M1.3%00.0%UnchangedHistory
RAPTRAPT Therapeutics, Inc.COM2,291,608$42.1M1.2%+492,653+27.4%AddedHistory
SNYSanofiSPONSORED ADR768,101$41.8M1.2%+768,101NewHistory
ADMAAdma Biologics, Inc.COM11,900,255$39.4M1.2%00.0%UnchangedHistory
NTRANatera, Inc.COM707,214$39.3M1.2%+577,214+444.0%AddedHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$38.2M1.1%00.0%UnchangedHistory
APLSApellis Pharmaceuticals, Inc.COM555,344$36.6M1.1%+555,344NewHistory
MGTXMeiraGTx Holdings plcCOM6,963,277$36.0M1.1%00.0%UnchangedHistory
SRPTSarepta Therapeutics, Inc.COM260,858$36.0M1.1%−388,392−59.8%ReducedHistory
Bellus Health Inc New07987C204COM NEW4,952,538$35.7M1.1%−3,938,489−44.3%Reduced–
CBAYCymaBay Therapeutics, Inc.COM3,903,255$34.0M1.0%+3,194,262+450.5%AddedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$32.8M1.0%00.0%UnchangedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$32.0M0.9%00.0%UnchangedHistory
ESTAEstablishment Labs Holdings Inc.COM467,857$31.7M0.9%−30,000−6.0%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,907,033$31.6M0.9%+210,000+12.4%AddedHistory
ZYMEZymeworks Inc.COM3,378,498$30.5M0.9%−1,132,777−25.1%ReducedHistory
ATXSAstria Therapeutics, Inc.COM2,189,462$29.1M0.9%00.0%UnchangedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$25.2M0.7%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM2,282,324$24.6M0.7%−925,117−28.8%ReducedHistory
IMTXImmatics N.V.SHS3,491,500$24.1M0.7%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM965,152$22.2M0.7%+965,152NewHistory
OMOutset Medical, Inc.COM1,089,427$20.0M0.6%00.0%UnchangedHistory
IMVTImmunovant, Inc.COM1,291,858$20.0M0.6%+1,141,858+761.2%AddedHistory
AKROAkero Therapeutics, Inc.COM523,525$20.0M0.6%+173,000+49.4%AddedHistory
ROIVRoivant Sciences Ltd.SHS2,692,136$19.9M0.6%+710,566+35.9%AddedHistory
LYRALyra Therapeutics, Inc.COM9,146,730$18.4M0.5%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$16.6M0.5%00.0%UnchangedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$16.3M0.5%00.0%UnchangedHistory
TERNTerns Pharmaceuticals, Inc.COM1,350,000$16.0M0.5%+1,350,000NewHistory
VBIVVBI Vaccines Inc/BCCOM NEW52,335,002$15.9M0.5%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM867,732$14.9M0.4%−210,472−19.5%ReducedHistory
VKTXViking Therapeutics, Inc.COM871,747$14.5M0.4%+871,747NewHistory
MIRMMirum Pharmaceuticals, Inc.COM601,566$14.4M0.4%+601,566NewHistory
Rain Oncology Inc.75082Q105COM1,648,215$14.4M0.4%−835,404−33.6%Reduced–
AORTArtivion, Inc.COM1,085,860$14.2M0.4%00.0%UnchangedHistory
AXGNAxogen, Inc.COM1,409,791$13.3M0.4%+21,665+1.6%AddedHistory
ISRGIntuitive Surgical IncCOM NEW50,000$12.8M0.4%+10,000+25.0%AddedHistory
ISEEIVERIC bio, Inc.COM500,000$12.2M0.4%−87,400−14.9%ReducedHistory
LONALeonaBio, Inc.COM4,797,278$12.0M0.4%00.0%UnchangedHistory
CTKBCytek Biosciences, Inc.COM1,289,534$11.9M0.4%00.0%UnchangedHistory
PRTAProthena Corp Public Ltd CoSHS237,646$11.5M0.3%00.0%UnchangedHistory
TCMDTactile Systems Technology IncCOM639,877$10.5M0.3%+639,877NewHistory
FUSNFusion Pharmaceuticals Inc.COM2,759,936$10.4M0.3%+2,759,936NewHistory
LRMRLarimar Therapeutics, Inc.COM2,280,709$10.3M0.3%−579,291−20.3%ReducedHistory
NBIXNeurocrine Biosciences IncStock100,050$10.1M0.3%00.0%UnchangedHistory
BMEABiomea Fusion, Inc.COM325,000$10.1M0.3%+325,000NewHistory
MORFMorphic Holding, Inc.COM256,737$9.66M0.3%−106,460−29.3%ReducedHistory
CMAXCareMax, Inc.COM CL A3,576,040$9.55M0.3%+446,845+14.3%AddedHistory
TYRATyra Biosciences, Inc.COM494,403$7.95M0.2%00.0%UnchangedHistory
BLPHBellerophon Therapeutics, Inc.COM NEW930,000$7.34M0.2%+930,000NewHistory
HLVXHilleVax, Inc.COM406,024$6.71M0.2%00.0%UnchangedHistory
CABACabaletta Bio, Inc.COM724,777$5.99M0.2%+407,323+128.3%AddedHistory
AVDLAvadel Pharmaceuticals PLCSPONSORED ADR590,000$5.40M0.2%+590,000NewHistory
VERUVeru Inc.COM4,298,212$4.99M0.1%−3,559,799−45.3%ReducedHistory
LABPLandos Biopharma, Inc.COM14,869,915$4.43M0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM3,282,275$3.97M0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM4,545,454$3.95M0.1%+4,545,454NewHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.83M0.1%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$3.74M0.1%00.0%UnchangedHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$3.66M0.1%00.0%UnchangedHistory
VIRVir Biotechnology, Inc.COM142,194$3.31M0.1%+142,194NewHistory
HRMYHarmony Biosciences Holdings, Inc.COM100,000$3.27M0.1%−311,804−75.7%ReducedHistory
ADCTADC Therapeutics SASHS1,495,805$2.92M0.1%+1,495,805NewHistory
CELLBruker Cellular Analysis, Inc.COM2,506,442$2.91M0.1%+2,506,442NewHistory
KRONKronos Bio, Inc.COM1,752,745$2.56M0.1%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM6,726,496$2.29M0.1%00.0%UnchangedHistory
TVTXTravere Therapeutics, Inc.COM90,748$2.04M0.1%00.0%UnchangedHistory
QTRXQuanterix CorpCOM130,000$1.47M<0.1%+130,000NewHistory
DRIODarioHealth Corp.COM NEW313,869$1.29M<0.1%−14,000−4.3%ReducedHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$1.27M<0.1%00.0%UnchangedHistory
ATNXAthenex, Inc.COM NEW776,623$1.03M<0.1%00.0%UnchangedConverted for a 1-for-20 splitHistory
TARAProtara Therapeutics, Inc.COM STK290,051$907.9K<0.1%00.0%UnchangedHistory
PEARPear Therapeutics, Inc.CLASS A COM900,548$229.6K<0.1%00.0%UnchangedHistory
MOTSMotus GI Holdings, Inc.COM NEW90,027$87.6K<0.1%00.0%UnchangedHistory
EQRx, Inc.26886C115*W EXP 12/17/202250,000$43.1K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$28.9K<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$16.7K<0.1%00.0%Unchanged–

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q1 2023
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$7.62M–

Sold out since Q4 2022 (14)

Positions held at the end of Q4 2022 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q4 2022
SecurityClassShares in Q4 2022Value in Q4 2022% of portfolio in Q4 2022History
HZNPHorizon Therapeutics Public Ltd CoSHS960,000$109.2M3.1%History
ALBOAlbireo Pharma, Inc.COM1,757,160$38.0M1.1%History
CINCCinCor Pharma, Inc.COM2,576,325$31.7M0.9%History
RVNCRevance Therapeutics, Inc.COM729,097$13.5M0.4%History
DICEDICE Therapeutics, Inc.COM293,362$9.15M0.3%History
SCPHscPharmaceuticals Inc.COM952,380$6.83M0.2%History
ISOIsoPlexis CorpCOM4,095,498$6.35M0.2%History
PENPenumbra IncCOM25,400$5.65M0.2%History
ACRSAclaris Therapeutics, Inc.COM341,239$5.37M0.2%History
PNTPOINT Biopharma Global Inc.COM500,000$3.65M0.1%History
PRCTPROCEPT BioRobotics CorpCOM64,537$2.68M0.1%History
PRVAPrivia Health Group, Inc.COM90,000$2.04M0.1%History
ABOSAcumen Pharmaceuticals, Inc.COM347,450$1.88M0.1%History
NVRONevro CorpCOM30,000$1.19M<0.1%History