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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q1 2023

Holdings as of Mar 31, 2023, filed May 16, 2023. Long positions only; changes compare share counts with Q4 2022.

Institution overview
Positions
98
+4 vs. Q4 2022
Portfolio value
$3.38B
−$90.3M (−2.6%) vs. Q4 2022
Filed
May 16, 2023
AmendedSEC
Holdings of Perceptive Advisors LLC in Q1 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$16.7K<0.1%00.0%Unchanged–
CareMax, Inc.14171W111*W EXP 06/08/20260,000$28.9K<0.1%00.0%Unchanged–
EQRx, Inc.26886C115*W EXP 12/17/202250,000$43.1K<0.1%00.0%Unchanged–
MOTSMotus GI Holdings, Inc.COM NEW90,027$87.6K<0.1%00.0%UnchangedHistory
PEARPear Therapeutics, Inc.CLASS A COM900,548$229.6K<0.1%00.0%UnchangedHistory
TARAProtara Therapeutics, Inc.COM STK290,051$907.9K<0.1%00.0%UnchangedHistory
ATNXAthenex, Inc.COM NEW776,623$1.03M<0.1%00.0%UnchangedConverted for a 1-for-20 splitHistory
CLOVClover Health Investments, Corp.COM CL A1,500,000$1.27M<0.1%00.0%UnchangedHistory
DRIODarioHealth Corp.COM NEW313,869$1.29M<0.1%−14,000−4.3%ReducedHistory
QTRXQuanterix CorpCOM130,000$1.47M<0.1%+130,000NewHistory
TVTXTravere Therapeutics, Inc.COM90,748$2.04M0.1%00.0%UnchangedHistory
CYPHCypherpunk Technologies Inc.COM6,726,496$2.29M0.1%00.0%UnchangedHistory
KRONKronos Bio, Inc.COM1,752,745$2.56M0.1%00.0%UnchangedHistory
CELLBruker Cellular Analysis, Inc.COM2,506,442$2.91M0.1%+2,506,442NewHistory
ADCTADC Therapeutics SASHS1,495,805$2.92M0.1%+1,495,805NewHistory
HRMYHarmony Biosciences Holdings, Inc.COM100,000$3.27M0.1%−311,804−75.7%ReducedHistory
VIRVir Biotechnology, Inc.COM142,194$3.31M0.1%+142,194NewHistory
NVNOenVVeno Medical CorpCOMMON STOCK781,615$3.66M0.1%00.0%UnchangedHistory
NBTXNanobiotix S.A.SPONSORED ADS1,059,800$3.74M0.1%00.0%UnchangedHistory
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.83M0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM4,545,454$3.95M0.1%+4,545,454NewHistory
OMICSingular Genomics Systems, Inc.COM3,282,275$3.97M0.1%00.0%UnchangedHistory
LABPLandos Biopharma, Inc.COM14,869,915$4.43M0.1%00.0%UnchangedHistory
VERUVeru Inc.COM4,298,212$4.99M0.1%−3,559,799−45.3%ReducedHistory
AVDLAvadel Pharmaceuticals PLCSPONSORED ADR590,000$5.40M0.2%+590,000NewHistory
CABACabaletta Bio, Inc.COM724,777$5.99M0.2%+407,323+128.3%AddedHistory
HLVXHilleVax, Inc.COM406,024$6.71M0.2%00.0%UnchangedHistory
BLPHBellerophon Therapeutics, Inc.COM NEW930,000$7.34M0.2%+930,000NewHistory
TYRATyra Biosciences, Inc.COM494,403$7.95M0.2%00.0%UnchangedHistory
CMAXCareMax, Inc.COM CL A3,576,040$9.55M0.3%+446,845+14.3%AddedHistory
MORFMorphic Holding, Inc.COM256,737$9.66M0.3%−106,460−29.3%ReducedHistory
BMEABiomea Fusion, Inc.COM325,000$10.1M0.3%+325,000NewHistory
NBIXNeurocrine Biosciences IncStock100,050$10.1M0.3%00.0%UnchangedHistory
LRMRLarimar Therapeutics, Inc.COM2,280,709$10.3M0.3%−579,291−20.3%ReducedHistory
FUSNFusion Pharmaceuticals Inc.COM2,759,936$10.4M0.3%+2,759,936NewHistory
TCMDTactile Systems Technology IncCOM639,877$10.5M0.3%+639,877NewHistory
PRTAProthena Corp Public Ltd CoSHS237,646$11.5M0.3%00.0%UnchangedHistory
CTKBCytek Biosciences, Inc.COM1,289,534$11.9M0.4%00.0%UnchangedHistory
LONALeonaBio, Inc.COM4,797,278$12.0M0.4%00.0%UnchangedHistory
ISEEIVERIC bio, Inc.COM500,000$12.2M0.4%−87,400−14.9%ReducedHistory
ISRGIntuitive Surgical IncCOM NEW50,000$12.8M0.4%+10,000+25.0%AddedHistory
AXGNAxogen, Inc.COM1,409,791$13.3M0.4%+21,665+1.6%AddedHistory
AORTArtivion, Inc.COM1,085,860$14.2M0.4%00.0%UnchangedHistory
Rain Oncology Inc.75082Q105COM1,648,215$14.4M0.4%−835,404−33.6%Reduced–
MIRMMirum Pharmaceuticals, Inc.COM601,566$14.4M0.4%+601,566NewHistory
VKTXViking Therapeutics, Inc.COM871,747$14.5M0.4%+871,747NewHistory
RCKTRocket Pharmaceuticals, Inc.COM867,732$14.9M0.4%−210,472−19.5%ReducedHistory
VBIVVBI Vaccines Inc/BCCOM NEW52,335,002$15.9M0.5%00.0%UnchangedHistory
TERNTerns Pharmaceuticals, Inc.COM1,350,000$16.0M0.5%+1,350,000NewHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$16.3M0.5%00.0%UnchangedHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$16.6M0.5%00.0%UnchangedHistory
LYRALyra Therapeutics, Inc.COM9,146,730$18.4M0.5%00.0%UnchangedHistory
ROIVRoivant Sciences Ltd.SHS2,692,136$19.9M0.6%+710,566+35.9%AddedHistory
AKROAkero Therapeutics, Inc.COM523,525$20.0M0.6%+173,000+49.4%AddedHistory
IMVTImmunovant, Inc.COM1,291,858$20.0M0.6%+1,141,858+761.2%AddedHistory
OMOutset Medical, Inc.COM1,089,427$20.0M0.6%00.0%UnchangedHistory
PTGXProtagonist Therapeutics, IncCOM965,152$22.2M0.7%+965,152NewHistory
IMTXImmatics N.V.SHS3,491,500$24.1M0.7%00.0%UnchangedHistory
COGTCogent Biosciences, Inc.COM2,282,324$24.6M0.7%−925,117−28.8%ReducedHistory
NAUTNautilus Biotechnology, Inc.COM9,111,151$25.2M0.7%00.0%UnchangedHistory
ATXSAstria Therapeutics, Inc.COM2,189,462$29.1M0.9%00.0%UnchangedHistory
ZYMEZymeworks Inc.COM3,378,498$30.5M0.9%−1,132,777−25.1%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,907,033$31.6M0.9%+210,000+12.4%AddedHistory
ESTAEstablishment Labs Holdings Inc.COM467,857$31.7M0.9%−30,000−6.0%ReducedHistory
RLAYRelay Therapeutics, Inc.COM1,943,097$32.0M0.9%00.0%UnchangedHistory
VRCAVerrica Pharmaceuticals Inc.COM5,038,983$32.8M1.0%00.0%UnchangedHistory
CBAYCymaBay Therapeutics, Inc.COM3,903,255$34.0M1.0%+3,194,262+450.5%AddedHistory
Bellus Health Inc New07987C204COM NEW4,952,538$35.7M1.1%−3,938,489−44.3%Reduced–
SRPTSarepta Therapeutics, Inc.COM260,858$36.0M1.1%−388,392−59.8%ReducedHistory
MGTXMeiraGTx Holdings plcCOM6,963,277$36.0M1.1%00.0%UnchangedHistory
APLSApellis Pharmaceuticals, Inc.COM555,344$36.6M1.1%+555,344NewHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$38.2M1.1%00.0%UnchangedHistory
NTRANatera, Inc.COM707,214$39.3M1.2%+577,214+444.0%AddedHistory
ADMAAdma Biologics, Inc.COM11,900,255$39.4M1.2%00.0%UnchangedHistory
SNYSanofiSPONSORED ADR768,101$41.8M1.2%+768,101NewHistory
RAPTRAPT Therapeutics, Inc.COM2,291,608$42.1M1.2%+492,653+27.4%AddedHistory
PCVXVaxcyte, Inc.COM1,170,000$43.9M1.3%00.0%UnchangedHistory
VRDNViridian Therapeutics, Inc.COM1,736,386$44.2M1.3%+515,811+42.3%AddedHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,278,226$44.6M1.3%+2,278,226NewHistory
SWTXSpringWorks Therapeutics, Inc.COM2,079,352$53.5M1.6%−538,339−20.6%ReducedHistory
VRNAVerona Pharma plcSPONSORED ADS2,733,790$54.9M1.6%−2,146,929−44.0%ReducedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM3,554,887$57.1M1.7%−484,389−12.0%ReducedHistory
MRTXMirati Therapeutics, Inc.COM1,574,134$58.5M1.7%−617,291−28.2%ReducedHistory
NUVLNuvalent, Inc.COM2,300,048$60.0M1.8%+45,041+2.0%AddedHistory
TMCITreace Medical Concepts, Inc.COM2,442,250$61.5M1.8%+495,847+25.5%AddedHistory
BMRNBiomarin Pharmaceutical IncCOM673,060$65.4M1.9%+166,579+32.9%AddedHistory
XENEXenon Pharmaceuticals Inc.COM1,832,174$65.6M1.9%−89,099−4.6%ReducedHistory
INBXInhibrx Biosciences, Inc.COM3,615,383$68.2M2.0%+301,600+9.1%AddedHistory
IOVAIovance Biotherapeutics, Inc.COM15,339,735$93.7M2.8%+5,367,955+53.8%AddedHistory
ALDXAldeyra Therapeutics, Inc.COM11,350,085$112.7M3.3%00.0%UnchangedHistory
LIANYLianBioSPONSORED ADS57,558,451$112.8M3.3%00.0%UnchangedHistory
ACLXArcellx, Inc.COMMON STOCK3,841,739$118.4M3.5%+1,243,434+47.9%AddedHistory
RXDXPrometheus Biosciences, Inc.COM1,272,694$136.6M4.0%+60,000+4.9%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM650,562$157.6M4.7%−81,370−11.1%ReducedHistory
CERECerevel Therapeutics Holdings, Inc.COM6,511,727$158.9M4.7%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM6,034,644$177.1M5.2%−53,689−0.9%ReducedHistory
RETAReata Pharmaceuticals IncCL A2,169,276$197.2M5.8%+2,169,276NewHistory
FOLDAmicus Therapeutics, Inc.COM27,662,917$306.8M9.1%+20,000+0.1%AddedHistory

Options (1)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q1 2023
SecurityClassPutsCalls
State Street SPDR S&P Biotech ETF78464A870ETF$7.62M–

Sold out since Q4 2022 (14)

Positions held at the end of Q4 2022 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q4 2022
SecurityClassShares in Q4 2022Value in Q4 2022% of portfolio in Q4 2022History
HZNPHorizon Therapeutics Public Ltd CoSHS960,000$109.2M3.1%History
ALBOAlbireo Pharma, Inc.COM1,757,160$38.0M1.1%History
CINCCinCor Pharma, Inc.COM2,576,325$31.7M0.9%History
RVNCRevance Therapeutics, Inc.COM729,097$13.5M0.4%History
DICEDICE Therapeutics, Inc.COM293,362$9.15M0.3%History
SCPHscPharmaceuticals Inc.COM952,380$6.83M0.2%History
ISOIsoPlexis CorpCOM4,095,498$6.35M0.2%History
PENPenumbra IncCOM25,400$5.65M0.2%History
ACRSAclaris Therapeutics, Inc.COM341,239$5.37M0.2%History
PNTPOINT Biopharma Global Inc.COM500,000$3.65M0.1%History
PRCTPROCEPT BioRobotics CorpCOM64,537$2.68M0.1%History
PRVAPrivia Health Group, Inc.COM90,000$2.04M0.1%History
ABOSAcumen Pharmaceuticals, Inc.COM347,450$1.88M0.1%History
NVRONevro CorpCOM30,000$1.19M<0.1%History