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Livermore
Livermore
ZHEN

Perceptive Advisors LLC

SEC CIK
0001224962
Latest filing
Aug 14, 2026

Holdings in Q4 2023

Holdings as of Dec 31, 2023, filed Feb 26, 2024. Long positions only; changes compare share counts with Q3 2023.

Institution overview
Positions
97
+10 vs. Q3 2023
Portfolio value
$4.47B
+$1.50B (+50.4%) vs. Q3 2023
Filed
Feb 26, 2024
AmendedSEC
Holdings of Perceptive Advisors LLC in Q4 2023
SecurityClassSharesValue% of portfolioShare changeActionHistory
CareMax, Inc.14171W111*W EXP 06/08/20260,000$450<0.1%00.0%Unchanged–
Surrozen, Inc.86889P117*W EXP 08/01/203166,666$3.33K<0.1%00.0%Unchanged–
RVMDWRevolution Medicines, Inc.*W EXP 12/17/202250,000$82.5K<0.1%+250,000NewHistory
BCABBioAtla, Inc.COM73,000$179.6K<0.1%+73,000NewHistory
CYPHCypherpunk Technologies Inc.COM NEW44,971$186.4K<0.1%00.0%UnchangedHistory
VBIVVBI Vaccines Inc/BCCOM1,381,355$815.0K<0.1%00.0%UnchangedHistory
OMICSingular Genomics Systems, Inc.COM2,126,893$978.6K<0.1%−236,321−10.0%ReducedHistory
AMAMAmbrx Biopharma, Inc.COM78,811$1.12M<0.1%+78,811NewHistory
MORFMorphic Holding, Inc.COM56,980$1.65M<0.1%+56,980NewHistory
CMAXCareMax, Inc.COM CL A3,679,284$1.83M<0.1%−144,273−3.8%ReducedHistory
ESTAEstablishment Labs Holdings Inc.COM82,299$2.13M<0.1%−195,384−70.4%ReducedHistory
KRONKronos Bio, Inc.COM1,752,745$2.19M<0.1%00.0%UnchangedHistory
CYTKCytokinetics IncCOM NEW30,317$2.53M0.1%+30,317NewHistory
FBRXForte Biosciences, Inc.COM3,265,359$2.68M0.1%00.0%UnchangedHistory
XFORX4 Pharmaceuticals, IncCOM3,545,454$2.97M0.1%00.0%UnchangedHistory
ACADAcadia Pharmaceuticals IncCOM101,000$3.16M0.1%+101,000NewHistory
NVNOenVVeno Medical CorpCOMMON STOCK623,315$3.20M0.1%−158,300−20.3%ReducedHistory
TVTXTravere Therapeutics, Inc.COM400,000$3.60M0.1%00.0%UnchangedHistory
VERUVeru Inc.COM5,584,699$4.02M0.1%+4,494,821+412.4%AddedHistory
NBTXNanobiotix S.A.SPONSORED ADS555,066$4.04M0.1%00.0%UnchangedHistory
MLTXMoonLake ImmunotherapeuticsCLASS A ORD82,398$4.98M0.1%+82,398NewHistory
TYRATyra Biosciences, Inc.COM360,000$4.99M0.1%00.0%UnchangedHistory
LABPLandos Biopharma, Inc.COM NEW1,486,991$5.44M0.1%00.0%UnchangedHistory
AXGNAxogen, Inc.COM808,380$5.52M0.1%−67,518−7.7%ReducedHistory
MGNXMacrogenics IncCOM611,932$5.89M0.1%+611,932NewHistory
EWTXEdgewise Therapeutics, Inc.COM555,555$6.08M0.1%+555,555NewHistory
RGNXREGENXBIO Inc.COM342,408$6.15M0.1%+342,408NewHistory
COGTCogent Biosciences, Inc.COM1,122,958$6.60M0.1%−1,186,512−51.4%ReducedHistory
TERNTerns Pharmaceuticals, Inc.COM1,075,000$6.98M0.2%00.0%UnchangedHistory
OLMAOlema Pharmaceuticals, Inc.COM539,831$7.57M0.2%+539,831NewHistory
ITCIIntra-Cellular Therapies, Inc.COM108,000$7.73M0.2%+108,000NewHistory
PTGXProtagonist Therapeutics, IncCOM383,260$8.79M0.2%−671,013−63.6%ReducedHistory
TCMDTactile Systems Technology IncCOM707,159$10.1M0.2%00.0%UnchangedHistory
TNGXTango Therapeutics, Inc.COM1,111,870$11.0M0.2%−1,307,098−54.0%ReducedHistory
ZYMEZymeworks Inc.COM1,074,807$11.2M0.2%−371,316−25.7%ReducedHistory
AUTLAutolus Therapeutics plcSPON ADS1,831,167$11.8M0.3%+1,831,167NewHistory
LONALeonaBio, Inc.COM5,402,964$13.1M0.3%+605,686+12.6%AddedHistory
EYPTEyePoint, Inc.COM NEW589,646$13.6M0.3%+589,646NewHistory
APLTApplied Therapeutics, Inc.COM4,080,249$13.7M0.3%+4,080,249NewHistory
ARVNArvinas, Inc.COM354,082$14.6M0.3%+354,082NewHistory
ACRVAcrivon Therapeutics, Inc.COMMON STOCK3,007,858$14.8M0.3%00.0%UnchangedHistory
MIRMMirum Pharmaceuticals, Inc.COM534,942$15.8M0.4%−137,100−20.4%ReducedHistory
TMCITreace Medical Concepts, Inc.COM1,250,405$15.9M0.4%−583,655−31.8%ReducedHistory
ASNDAscendis Pharma A/SSPONSORED ADR132,176$16.6M0.4%+132,176NewHistory
AORTArtivion, Inc.COM931,352$16.7M0.4%00.0%UnchangedHistory
ISRGIntuitive Surgical IncCOM NEW55,000$18.6M0.4%+55,000NewHistory
SLDBSolid Biosciences Inc.COM NEW3,495,933$21.5M0.5%00.0%UnchangedHistory
CELCCelcuity Inc.COM1,481,300$21.6M0.5%+1,481,300NewHistory
OBIOOrchestra BioMed Holdings, Inc.COM2,432,089$22.2M0.5%00.0%UnchangedHistory
AKROAkero Therapeutics, Inc.COM967,775$22.6M0.5%−651,650−40.2%ReducedHistory
RVMDRevolution Medicines, Inc.COM818,882$23.5M0.5%−502,913−38.0%ReducedHistory
TARSTarsus Pharmaceuticals, Inc.COM1,296,416$26.3M0.6%00.0%UnchangedHistory
FUSNFusion Pharmaceuticals Inc.COM2,751,395$26.4M0.6%00.0%UnchangedHistory
AMLXAmylyx Pharmaceuticals, Inc.COM1,869,125$27.5M0.6%−819,748−30.5%ReducedHistory
ADMAAdma Biologics, Inc.COM6,433,369$29.1M0.7%−550,950−7.9%ReducedHistory
ALDXAldeyra Therapeutics, Inc.COM8,593,586$30.2M0.7%−2,756,499−24.3%ReducedHistory
ATXSAstria Therapeutics, Inc.COM4,004,070$30.8M0.7%+1,814,608+82.9%AddedHistory
MDGLMadrigal Pharmaceuticals, Inc.COM151,151$35.0M0.8%+26,514+21.3%AddedHistory
NBIXNeurocrine Biosciences IncStock270,794$35.7M0.8%+111,552+70.1%AddedHistory
IMTXImmatics N.V.SHS3,491,500$36.8M0.8%00.0%UnchangedHistory
ABBVAbbVie Inc.Stock238,000$36.9M0.8%+238,000NewHistory
NAUTNautilus Biotechnology, Inc.COM12,594,211$37.7M0.8%+3,483,060+38.2%AddedHistory
VRDNViridian Therapeutics, Inc.COM1,730,212$37.7M0.8%+719,007+71.1%AddedHistory
EOLSEvolus, Inc.COM3,963,424$41.7M0.9%+2,477,623+166.8%AddedHistory
SRPTSarepta Therapeutics, Inc.COM451,873$43.6M1.0%+269,153+147.3%AddedHistory
CRNXCrinetics Pharmaceuticals, Inc.COM1,255,512$44.7M1.0%−8,220−0.7%ReducedHistory
CABACabaletta Bio, Inc.COM2,003,058$45.5M1.0%+870,567+76.9%AddedHistory
RYZBRayzeBio, Inc.COM744,056$46.3M1.0%−32,749−4.2%ReducedHistory
XENEXenon Pharmaceuticals Inc.COM1,100,748$50.7M1.1%+483,248+78.3%AddedHistory
APGEApogee Therapeutics, Inc.COM1,827,901$51.1M1.1%00.0%UnchangedHistory
RCKTRocket Pharmaceuticals, Inc.COM1,707,398$51.2M1.1%+189,931+12.5%AddedHistory
VRCAVerrica Pharmaceuticals Inc.COM7,099,182$52.0M1.2%+2,060,199+40.9%AddedHistory
RAPTRAPT Therapeutics, Inc.COM2,139,950$53.2M1.2%+219,292+11.4%AddedHistory
NTRANatera, Inc.COM850,225$53.3M1.2%+632,047+289.7%AddedHistory
SYRESpyre Therapeutics, Inc.COM NEW2,606,679$56.1M1.3%+2,525,563+3,113.5%AddedHistory
IRONDisc Medicine, Inc.COM1,023,045$59.1M1.3%+127,404+14.2%AddedHistory
LYRALyra Therapeutics, Inc.COM12,757,562$66.8M1.5%00.0%UnchangedHistory
PCVXVaxcyte, Inc.COM1,088,486$68.4M1.5%−254,265−18.9%ReducedHistory
BBIOBridgeBio Pharma, Inc.COM1,748,933$70.6M1.6%00.0%UnchangedHistory
SWTXSpringWorks Therapeutics, Inc.COM1,957,246$71.4M1.6%+436,830+28.7%AddedHistory
BHVNBiohaven Ltd.COM1,725,047$73.8M1.7%+973,227+129.4%AddedHistory
VRNAVerona Pharma plcSPONSORED ADS3,866,214$76.9M1.7%−140,983−3.5%ReducedHistory
MGTXMeiraGTx Holdings plcCOM11,331,103$79.5M1.8%00.0%UnchangedHistory
CRGXCARGO Therapeutics, Inc.COM3,436,600$79.6M1.8%+3,436,600NewHistory
MDTMedtronic plcStock976,652$80.5M1.8%+389,652+66.4%AddedHistory
AXSMAxsome Therapeutics, Inc.COM1,038,019$82.6M1.8%+556,370+115.5%AddedHistory
CBAYCymaBay Therapeutics, Inc.COM4,024,400$95.1M2.1%−18,791−0.5%ReducedHistory
IOVAIovance Biotherapeutics, Inc.COM11,979,415$97.4M2.2%+16,477+0.1%AddedHistory
IMVTImmunovant, Inc.COM2,328,082$98.1M2.2%−1,486,609−39.0%ReducedHistory
RYTMRhythm Pharmaceuticals, Inc.COM2,154,110$99.0M2.2%+1,773,282+465.6%AddedHistory
SLNOSoleno Therapeutics IncCOM3,074,542$123.8M2.8%00.0%UnchangedHistory
INBXInhibrx Biosciences, Inc.COM4,256,104$161.7M3.6%00.0%UnchangedHistory
NUVLNuvalent, Inc.COM2,917,991$214.7M4.8%+454,540+18.5%AddedHistory
ACLXArcellx, Inc.COMMON STOCK4,544,809$252.2M5.6%+578,831+14.6%AddedHistory
LIANYLianBioSPONSORED ADS57,558,451$257.3M5.8%00.0%UnchangedHistory
FOLDAmicus Therapeutics, Inc.COM28,057,456$398.1M8.9%+364,539+1.3%AddedHistory
CERECerevel Therapeutics Holdings, Inc.COM10,965,193$464.9M10.4%+876,808+8.7%AddedHistory

Options (4)

Puts and calls in the same filing. Amounts are the market value of the underlying shares, which is what 13F reports.

Option positions of Perceptive Advisors LLC in Q4 2023
SecurityClassPutsCalls
NVAXNovavax IncCOM NEW$4.75M–
State Street SPDR S&P Biotech ETF78464A870ETF$1.28M–
APLTApplied Therapeutics, Inc.COM–$500.0K
EYPTEyePoint, Inc.COM NEW$37.5K–

Sold out since Q3 2023 (11)

Positions held at the end of Q3 2023 that are gone from this filing.

Positions of Perceptive Advisors LLC sold out since Q3 2023
SecurityClassShares in Q3 2023Value in Q3 2023% of portfolio in Q3 2023History
ARGXArgenx SESPONSORED ADR150,600$74.0M2.5%History
ROIVRoivant Sciences Ltd.SHS3,819,456$44.6M1.5%History
HRMYHarmony Biosciences Holdings, Inc.COM996,306$32.6M1.1%History
RLAYRelay Therapeutics, Inc.COM1,943,097$16.3M0.5%History
BMEABiomea Fusion, Inc.COM716,441$9.86M0.3%History
PRTAProthena Corp Public Ltd CoSHS165,615$7.99M0.3%History
OMOutset Medical, Inc.COM661,977$7.20M0.2%History
SLGCSomaLogic, Inc.CLASS A COM1,500,000$3.58M0.1%History
SLRNACELYRIN, Inc.COM200,000$2.03M0.1%History
MOTSMotus GI Holdings, Inc.COM NEW90,027$40.5K<0.1%History
EQRx, Inc.26886C115*W EXP 12/17/202250,000$10.0K<0.1%–