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EcoR1 Capital, LLC

In the past year, 2 open-market purchase filings worth $44.7M and 1 sale filing worth $65.0M.

Current role at each company

Show 10 more companies

Open-market trades in the past year

Open-market purchases (P) and sales (S) filed in the last 365 days, not counting derivative securities or duplicate filings. Values leave out price outliers.

Bought
$44.7M
2 filings
Sold
$65.0M
1 filing
Net
−$20.2M
Bought minus sold
Companies
3
With open-market trades

Trades

Every Form 4 that lists EcoR1 Capital, LLC as a reporting owner, including filings made jointly with others, grouped by company. Each row adds up one type of transaction in one filing. Only open-market purchases (P) and sales (S) are shown by default.

ATRA Atara Biotherapeutics, Inc.

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
May 11, 2026 (view filing)May 74 daysEcoR1 Capital, LLC10% OwnerPPurchase+507.4K$9.35+$4.74M+48.6%1.55M after

TRAX First Tracks Biotherapeutics, Inc.

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Apr 22, 2026 (view filing)Apr 202 daysEcoR1 Capital, LLC10% OwnerSSale+4.71M$13.81+$65.0MNew position3.17M after

AKTS Aktis Oncology, Inc.

Director1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jan 12, 2026 (view filing)8:28 PM ETJan 12Same dayNodelman Oleg and 1 otherDirectorPPurchase+2.22M$18.00+$40.0MNew position347.3K after2 lots

ADAPY Adaptimmune Therapeutics PLC

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jul 30, 2025 (view filing)6:20 PM ETJul 28-302 daysEcoR1 Capital, LLC10% OwnerSSale−64.1M$0.1076−$6.89M−39.0%100.4M after3 lotsPrice outlier

ZYME Zymeworks Inc.

Director, 10% Owner20 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jan 12, 2023 (view filing)Jan 10-112 daysEcoR1 Capital, LLC10% OwnerPPurchase+1.03M$7.67+$7.87M+13.6%8.59M after2 lots
Jan 18, 2023 (view filing)Jan 13-185 daysEcoR1 Capital, LLC10% OwnerPPurchase+985.1K$9.84+$9.70M+11.5%9.58M after3 lots
Jan 23, 2023 (view filing)Jan 19-204 daysEcoR1 Capital, LLC10% OwnerPPurchase+307.5K$9.70+$2.98M+3.2%9.89M after2 lots
Mar 30, 2023 (view filing)Mar 282 daysEcoR1 Capital, LLC10% OwnerPPurchase+200.0K$8.00+$1.60M+2.0%10.1M after
Jun 21, 2023 (view filing)Jun 165 daysEcoR1 Capital, LLC10% OwnerPPurchase+3.35M$8.12+$27.2M+33.2%13.4M after
Dec 28, 2023 (view filing)Dec 262 daysEcoR1 Capital, LLC10% OwnerPPurchase+5.09M$9.83+$50.0M–5.09M afterDerivative
Dec 26, 2024 (view filing)Dec 19-237 daysEcoR1 Capital, LLCDirector, 10% OwnerPPurchase+1.25M$13.98+$17.5M+9.3%14.7M afterAmended3 lots
Dec 27, 2024 (view filing)Dec 24-273 daysEcoR1 Capital, LLCDirector, 10% OwnerPPurchase+130.3K$14.44+$1.88M+0.9%14.8M after3 lots
Jan 2, 2025 (view filing)Dec 30, 2024-Jan 2, 20253 daysEcoR1 Capital, LLCDirector, 10% OwnerPPurchase+363.4K$14.65+$5.32M+2.5%15.2M after3 lots
Jan 10, 2025 (view filing)Jan 8-102 daysEcoR1 Capital, LLCDirector, 10% OwnerPPurchase+225.1K$13.22+$2.98M+1.5%15.4M after2 lots

See all 20 trades at ZYME

ITOS iTeos Therapeutics, Inc.

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
May 16, 2025 (view filing)May 14-152 daysEcoR1 Capital, LLC10% OwnerPPurchase+4.96M$7.80+$38.7M+86.5%10.7M after2 lots

PRTA Prothena Corp Public Ltd Co

10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jan 12, 2022 (view filing)Jan 12Same dayEcoR1 Capital, LLC10% OwnerPPurchase+300.0K$37.50+$11.3M+2.7%11.6M after
May 9, 2022 (view filing)May 54 daysEcoR1 Capital, LLC10% OwnerPPurchase+1.06M$29.02+$30.8M+10.1%11.6M after
May 9, 2022 (view filing)May 54 daysEcoR1 Capital, LLC10% OwnerSSale−1.06M$29.02−$30.8M−8.4%11.6M after
May 6, 2025 (view filing)May 2-64 daysEcoR1 Capital, LLC10% OwnerSSale−6.28M$8.09−$50.8M−54.2%5.30M after3 lots

ANAB Anaptysbio, Inc

Director, 10% Owner4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
May 9, 2022 (view filing)6:04 AM ETMay 54 daysNodelman Oleg and 1 otherDirector, 10% OwnerPPurchase+668.2K$21.63+$14.5M+9.8%7.52M after
May 9, 2022 (view filing)6:04 AM ETMay 54 daysNodelman Oleg and 1 otherDirector, 10% OwnerSSale−668.2K$21.63−$14.5M−8.2%7.52M after
Aug 16, 2024 (view filing)Aug 142 daysEcoR1 Capital, LLC10% OwnerPPurchase+274.0K$36.50+$10.0M+3.6%7.79M after
Jan 2, 2025 (view filing)6:17 PM ETDec 30, 2024-Jan 2, 20253 daysNodelman Oleg and 1 otherDirector, 10% OwnerPPurchase+85.1K$12.92+$1.10M+1.1%7.88M after3 lots

TNGX Tango Therapeutics, Inc.

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Nov 8, 2024 (view filing)Nov 6-72 daysEcoR1 Capital, LLC10% OwnerSSale−2.70M$3.13−$8.45M−20.3%10.6M after3 lots

NUVB Nuvation Bio Inc.

Director4 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Nov 30, 2021 (view filing)6:07 PM ETMar 31-Nov 24244 daysLateNodelman Oleg and 5 othersDirectorPPurchaseClass A Common Stock+393.2K$8.89+$3.49M+50.7%1.17M after4 lots
Nov 30, 2021 (view filing)6:07 PM ETMar 31244 daysLateNodelman Oleg and 5 othersDirectorSSaleClass A Common Stock+151.5K$10.45+$1.58M+15.2%1.15M after
Nov 30, 2021 (view filing)6:07 PM ETJul 31122 daysLateNodelman Oleg and 5 othersDirectorSSaleClass A Common Stock−56.6K$8.64−$489.0K−4.7%1.15M after
Sep 22, 2023 (view filing)3:44 PM ETSep 19-213 daysNodelman Oleg and 5 othersDirectorPPurchaseClass A Common Stock+5.31M$1.26+$6.69M+72.2%12.7M afterAmended3 lots

VYGR Voyager Therapeutics, Inc.

10% Owner2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Jun 23, 2022 (view filing)Jun 21-232 daysEcoR1 Capital, LLC10% OwnerPPurchase+477.4K$5.58+$2.66M+11.2%4.75M after2 lots
Jan 11, 2023 (view filing)Jan 9-112 daysEcoR1 Capital, LLC10% OwnerSSale−902.4K$7.91−$7.14M−19.0%3.85M after3 lots

ODT Odonate Therapeutics, Inc.

10% Owner2 trades

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Dec 10, 2021 (view filing)Dec 19 daysLateEcoR1 Capital, LLC10% OwnerPPurchase+185.9K$1.66+$308.7K+3.4%5.70M after
Dec 10, 2021 (view filing)Dec 1-109 daysLateEcoR1 Capital, LLC10% OwnerSSale−5.89M$1.65−$9.74M−100.0%0 after4 lots

CRVS Corvus Pharmaceuticals, Inc.

10% Owner1 trade

Insider trades
Filed (ET)Trade dateFiling delayInsiderTransactionSharesAvg priceValueHolding changeFlags
Oct 1, 2021 (view filing)Sep 30-Oct 11 dayEcoR1 Capital, LLC10% OwnerSSale−5.00M$5.01−$25.0M−98.4%81.1K after2 lots