Skip to main content

Tyra Biosciences, Inc.

TYRA
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001863127

In the last 90 days, Tyra Biosciences, Inc. insiders filed 1 open-market purchase and 0 sales; 168 institutions reported holding it in 13F filings for Q2 2026, worth $2.22B in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Tyra Biosciences, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of TYRA: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1162133+19
Shares55.6M168.1K56.8M+1.36M (+2.4%)
Value$778.4M$2.35M$1.49B+$717.9M (+92.5%)

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (29)

Institutions that held Tyra Biosciences, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to TYRA in Q4 2025
InstitutionSharesValue% of portfolio
Trails Edge Capital Partners, LP700,000$18.4M4.55%
Boone Capital Management LLC398,482$10.5M3.29%
Elmind Capital, LP350,000$9.20M2.72%
Logos Global Management LP210,000$5.52M0.37%
BNP PARIBAS ASSET MANAGEMENT Holding S.A.129,779$3.41M0.00%
Soleus Capital Management, L.P.125,000$3.29M0.14%
Seven Fleet Capital Management LP79,560$2.09M1.42%
Kalehua Capital Management LLC74,465$1.96M1.94%
Superstring Capital Management LP58,677$1.54M0.83%
Susquehanna International Group, LLP55,135$1.45M0.00%
Algert Global LLC46,870$1.23M0.02%
Y-Intercept (Hong Kong) Ltd45,942$1.21M0.03%
ExodusPoint Capital Management, LP42,791$1.12M0.01%
Voya Investment Management LLC29,887$785.7K0.00%
Canada Pension Plan Investment Board28,900$759.8K0.00%
Fisher Asset Management, LLC28,800$757.2K0.00%
PSP Research LLC21,853$574.5K0.50%
Creative Planning19,603$515.4K0.00%
Rafferty Asset Management, LLC15,455$406.3K0.00%
Franklin Resources Inc12,970$341.0K0.00%
Bank of Nova Scotia11,100$291.8K0.00%
VARCOV Co.9,708$255.2K0.10%
Manufacturers Life Insurance Company, The8,357$219.7K0.00%
Bellevue Group AG3,143$82.6K0.00%
Caitong International Asset Management Co., Ltd2,997$78.8K0.02%
Chung Wu Investment Group, LLC2,000$52.6K0.04%
Smartleaf Asset Management LLC127$3.23K0.00%
Rockefeller Capital Management L.P.84$2.21K0.00%
Steward Partners Investment Advisory, LLC77$2.02K0.00%

Sold out (10)

Institutions that held Tyra Biosciences, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of TYRA in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Walleye Capital LLC297,808$4.17M
Renaissance Technologies LLC170,100$2.38M
Citadel Advisors LLC111,293$1.56M
Jump Financial, LLC62,000$867.4K
Jane Street Group, LLC44,680$625.1K
Brevan Howard Capital Management LP31,101$435.1K
Trexquant Investment LP15,758$220.5K
Tudor Investment Corp Et Al10,761$150.5K
SG Americas Securities, LLC9,542$133.0K
Rise Advisors, LLC49$686

Not filed for Q4 2025 yet (2)

Institutions that held Tyra Biosciences, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding TYRA in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
AXA Investment Managers S.A.128,789$1.80M
Cubist Systematic Strategies, LLC39,310$549.9K