Spero Therapeutics, Inc.
SPRO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001701108
No open-market purchases or sales by Spero Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $47.5M in total; no superinvestor holds it.
Q4 2024 vs. Q3 2024
How the institutions holding Spero Therapeutics, Inc. changed between Q3 2024 and Q4 2024.
All holders in Q4 2024All holders in Q3 2024
| Measure | Q3 2024 | Q4 2024 | Change |
|---|---|---|---|
| Holders | 46 | 50 | +4 |
| Shares | 12.3M | 15.7M | +3.34M (+27.0%) |
| Value | $16.5M | $16.1M | −$390.7K (−2.4%) |
New holders (12)
Institutions that held Spero Therapeutics, Inc. at the end of Q4 2024 but not at the end of Q3 2024.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| Pfizer Inc | 2,362,348 | $2.43M | 0.09% |
| Murchinson Ltd. | 873,910 | $900.1K | 0.41% |
| Monimus Capital Management, LP | 310,908 | $320.2K | 0.30% |
| Squarepoint Ops LLC | 55,051 | $56.7K | 0.00% |
| Jane Street Group, LLC | 52,869 | $54.5K | 0.00% |
| Prudential Financial Inc | 49,200 | $50.7K | 0.00% |
| Virtu Financial LLC | 46,046 | $47.0K | 0.00% |
| XTX Topco Ltd | 30,138 | $31.0K | 0.00% |
| HRT Financial LP | 14,692 | $15.0K | 0.00% |
| Texas Yale Capital Corp. | 10,000 | $10.3K | 0.00% |
| SBI Securities Co., Ltd. | 213 | $219 | 0.00% |
| Richards, Merrill & Peterson, Inc. | 150 | $155 | 0.00% |
Sold out (8)
Institutions that held Spero Therapeutics, Inc. at the end of Q3 2024 and filed for Q4 2024 without it.
| Institution | Shares, Q3 2024 | Value, Q3 2024 |
|---|---|---|
| Novo Holdings A/S | 468,902 | $628.3K |
| AWM Investment Company, Inc. | 333,400 | $446.8K |
| Man Group plc | 38,481 | $51.6K |
| Millennium Management LLC | 32,172 | $43.1K |
| Shay Capital LLC | 25,000 | $33.5K |
| Russell Investments Group, Ltd. | 6,400 | $8.58K |
| CIBC Private Wealth Group, LLC | 2,880 | $3.86K |
| Northwestern Mutual Wealth Management Co | 50 | $67 |