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Spero Therapeutics, Inc.

SPRO
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001701108

No open-market purchases or sales by Spero Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $47.5M in total; no superinvestor holds it.

Q4 2023 vs. Q3 2023

How the institutions holding Spero Therapeutics, Inc. changed between Q3 2023 and Q4 2023.

All holders in Q4 2023All holders in Q3 2023

13F holders of SPRO: Q3 2023 compared with Q4 2023
MeasureQ3 2023Of which not filed for Q4 2023Q4 2023Change
Holders54250−2
Shares14.2M1.60M13.8M+1.25M (+9.9%)
Value$17.2M$1.94M$19.6M+$4.42M (+29.1%)

2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so the changes leave them out.

New holders (6)

Institutions that held Spero Therapeutics, Inc. at the end of Q4 2023 but not at the end of Q3 2023.

Institutions new to SPRO in Q4 2023
InstitutionSharesValue% of portfolio
ADAR1 Capital Management, LLC1,067,711$1.57M0.70%
Citadel Advisors LLC32,274$47.4K0.00%
DLK Investment Management, LLC31,355$46.1K0.02%
Three Seasons Wealth, LLC15,000$22.1K0.02%
Two Sigma Securities, LLC10,301$15.1K0.00%
FMR LLC189$2780.00%

Sold out (8)

Institutions that held Spero Therapeutics, Inc. at the end of Q3 2023 and filed for Q4 2023 without it.

Institutions that sold out of SPRO in Q4 2023
InstitutionShares, Q3 2023Value, Q3 2023
Rock Springs Capital Management LP57,373$69.4K
HRT Financial LP18,627$22.0K
Two Sigma Investments, LP17,023$20.6K
ERn Financial, LLC15,766$19.1K
WR Wealth Planners, LLC2,600$3.15K
Cullen/Frost Bankers, Inc.2,000$2.42K
Beaird Harris Wealth Management, LLC202$245
Heritage Wealth Advisors187$226

Not filed for Q4 2023 yet (2)

Institutions that held Spero Therapeutics, Inc. at the end of Q3 2023 and haven't filed a 13F for Q4 2023. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding SPRO in Q3 2023 that haven't filed for Q4 2023
InstitutionShares, Q3 2023Value, Q3 2023
Atlas Venture Associates IX, LLC1,353,303$1.64M
OUP Management Co., LLC249,070$301.4K