Spero Therapeutics, Inc.
SPRO- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001701108
No open-market purchases or sales by Spero Therapeutics, Inc. insiders were filed in the last 90 days; 59 institutions reported holding it in 13F filings for Q2 2026, worth $47.5M in total; no superinvestor holds it.
Q4 2022 vs. Q3 2022
How the institutions holding Spero Therapeutics, Inc. changed between Q3 2022 and Q4 2022.
All holders in Q4 2022All holders in Q3 2022
| Measure | Q3 2022 | Q4 2022 | Change |
|---|---|---|---|
| Holders | 69 | 60 | −9 |
| Shares | 19.9M | 14.2M | −5.63M (−28.4%) |
| Value | $39.7M | $24.6M | −$15.1M (−38.1%) |
New holders (14)
Institutions that held Spero Therapeutics, Inc. at the end of Q4 2022 but not at the end of Q3 2022.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| XTX Topco Ltd | 346,734 | $599.9K | 0.13% |
| Two Sigma Investments, LP | 39,795 | $68.8K | 0.00% |
| Virtu Financial LLC | 34,369 | $59.0K | 0.01% |
| Charles Schwab Investment Management Inc | 28,565 | $49.4K | 0.00% |
| Two Sigma Securities, LLC | 23,523 | $40.7K | 0.01% |
| CI Private Wealth, LLC | 17,500 | $30.3K | 0.00% |
| Prudential Financial Inc | 14,600 | $25.3K | 0.00% |
| Invesco Ltd. | 12,073 | $20.9K | 0.00% |
| Texas Yale Capital Corp. | 10,000 | $17.3K | 0.00% |
| Colony Group LLC | 10,000 | $17.0K | 0.00% |
| Belpointe Asset Management LLC | 4,560 | $7.89K | 0.00% |
| CoreCap Advisors, LLC | 142 | $246 | 0.00% |
| GWM Advisors LLC | 100 | $0 | 0.00% |
| Steward Financial Group LLC | 354 | $0 | 0.00% |
Sold out (23)
Institutions that held Spero Therapeutics, Inc. at the end of Q3 2022 and filed for Q4 2022 without it.
| Institution | Shares, Q3 2022 | Value, Q3 2022 |
|---|---|---|
| Aquilo Capital Management, LLC | 3,403,210 | $6.81M |
| BVF Inc | 1,929,376 | $3.86M |
| Artal Group S.A. | 500,000 | $1.00M |
| Bank of Montreal | 202,300 | $415.0K |
| AQR Capital Management LLC | 186,682 | $373.0K |
| Letko, Brosseau & Associates Inc | 73,659 | $147.0K |
| Acadian Asset Management LLC | 61,152 | $121.0K |
| Goldman Sachs Group Inc | 55,438 | $111.0K |
| Williams Jones Wealth Management, LLC. | 19,000 | $38.0K |
| Squarepoint Ops LLC | 16,423 | $33.0K |
| Qube Research & Technologies Ltd | 15,948 | $32.0K |
| Jane Street Group, LLC | 15,496 | $31.0K |
| Weitzel Financial Services, Inc. | 14,200 | $28.4K |
| LMR Partners LLP | 11,508 | $23.0K |
| Man Group plc | 11,184 | $22.0K |
| Quantbot Technologies LP | 2,900 | $5.00K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 1,950 | $4.00K |
| Atlas Capital Advisors LLC | 727 | $1.45K |
| Citigroup Inc | 495 | $1.00K |
| Crewe Advisors LLC | 258 | $1.00K |
| China Universal Asset Management Co., Ltd. | 329 | $1.00K |
| Royal Bank of Canada | 43 | $0 |
| Daiwa Securities Group Inc. | 110 | $0 |