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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

Q2 2025 vs. Q1 2025

How the institutions holding Spruce Biosciences, Inc. changed between Q1 2025 and Q2 2025.

All holders in Q2 2025All holders in Q1 2025

13F holders of SPRB: Q1 2025 compared with Q2 2025
MeasureQ1 2025Q2 2025Change
Holders313−28
Shares10.5M2.05M−8.40M (−80.4%)
Value$3.03M$146.6K−$2.88M (−95.2%)

New holders (0)

Institutions that held Spruce Biosciences, Inc. at the end of Q2 2025 but not at the end of Q1 2025.

None.

Sold out (28)

Institutions that held Spruce Biosciences, Inc. at the end of Q1 2025 and filed for Q2 2025 without it.

Institutions that sold out of SPRB in Q2 2025
InstitutionShares, Q1 2025Value, Q1 2025
Carlyle Group Inc.2,896,518$840.3K
Rock Springs Capital Management LP2,609,125$756.9K
Vanguard Group Inc843,844$244.7K
ADAR1 Capital Management, LLC403,716$117.1K
Renaissance Technologies LLC382,900$111.1K
Boothbay Fund Management, LLC288,800$83.8K
Geode Capital Management, LLC276,708$80.3K
BlackRock, Inc.124,734$36.2K
UBS Group AG116,464$33.8K
Lion Point Capital, LP75,000$21.8K
State Street Corp60,700$17.6K
Two Sigma Securities, LLC47,686$13.8K
XTX Topco Ltd41,217$12.0K
Shay Capital LLC38,119$11.1K
Virtu Financial LLC39,426$11.0K
Jane Street Group, LLC37,429$10.9K
Northern Trust Corp32,721$9.49K
Two Sigma Investments, LP20,545$5.96K
Ground Swell Capital, LLC17,312$5.02K
Marex Group plc14,800$4.29K
Two Sigma Advisers, LP12,200$3.54K
Citigroup Inc11,083$3.21K
Morgan Stanley7,396$2.15K
Tower Research Capital LLC (TRC)4,697$1.36K
Group One Trading, L.P.1,153$334
Bank of America Corp233$68
BNP Paribas Arbitrage, SA181$52
JPMorgan Chase & Co65$19