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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

Q1 2025 vs. Q4 2024

How the institutions holding Spruce Biosciences, Inc. changed between Q4 2024 and Q1 2025.

All holders in Q1 2025All holders in Q4 2024

13F holders of SPRB: Q4 2024 compared with Q1 2025
MeasureQ4 2024Q1 2025Change
Holders31310
Shares11.2M10.5M−728.1K (−6.5%)
Value$4.69M$3.03M−$1.66M (−35.4%)

New holders (5)

Institutions that held Spruce Biosciences, Inc. at the end of Q1 2025 but not at the end of Q4 2024.

Institutions new to SPRB in Q1 2025
InstitutionSharesValue% of portfolio
Two Sigma Securities, LLC47,686$13.8K0.00%
Virtu Financial LLC39,426$11.0K0.00%
Jane Street Group, LLC37,429$10.9K0.00%
Ground Swell Capital, LLC17,312$5.02K0.01%
Citigroup Inc11,083$3.21K0.00%

Sold out (5)

Institutions that held Spruce Biosciences, Inc. at the end of Q4 2024 and filed for Q1 2025 without it.

Institutions that sold out of SPRB in Q1 2025
InstitutionShares, Q4 2024Value, Q4 2024
Sands Capital Ventures, LLC715,817$300.6K
Susquehanna International Group, LLP58,984$24.8K
HRT Financial LP37,838$15.0K
Bridgeway Capital Management, LLC34,900$14.7K
Simplex Trading, LLC4,857$2.00K