Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
Q1 2024 vs. Q4 2023
How the institutions holding Spruce Biosciences, Inc. changed between Q4 2023 and Q1 2024.
All holders in Q1 2024All holders in Q4 2023
| Measure | Q4 2023 | Q1 2024 | Change |
|---|---|---|---|
| Holders | 40 | 50 | +10 |
| Shares | 32.3M | 18.0M | −14.3M (−44.3%) |
| Value | $94.4M | $14.1M | −$80.3M (−85.0%) |
New holders (22)
Institutions that held Spruce Biosciences, Inc. at the end of Q1 2024 but not at the end of Q4 2023.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| Altium Capital Management LP | 1,150,000 | $903.8K | 0.40% |
| Acadian Asset Management LLC | 368,831 | $289.0K | 0.00% |
| ADAR1 Capital Management, LLC | 365,216 | $287.0K | 0.08% |
| Panagora Asset Management Inc | 253,682 | $199.4K | 0.00% |
| ExodusPoint Capital Management, LP | 224,833 | $177.0K | 0.00% |
| AWM Investment Company, Inc. | 200,000 | $157.2K | 0.02% |
| Walleye Capital LLC | 178,958 | $140.6K | 0.00% |
| Jane Street Group, LLC | 78,544 | $61.7K | 0.00% |
| Lion Point Capital, LP | 75,000 | $58.9K | 0.11% |
| Castleview Partners, LLC | 59,709 | $46.9K | 0.03% |
| XTX Topco Ltd | 56,747 | $44.6K | 0.01% |
| Dimensional Fund Advisors LP | 46,664 | $36.7K | 0.00% |
| Susquehanna International Group, LLP | 29,709 | $23.3K | 0.00% |
| Simplex Trading, LLC | 28,100 | $22.0K | 0.00% |
| Two Sigma Securities, LLC | 26,016 | $20.4K | 0.00% |
| Belvedere Trading LLC | 24,900 | $19.6K | 0.00% |
| Balyasny Asset Management LLC | 22,508 | $17.7K | 0.00% |
| Omers Administration Corp | 16,000 | $12.6K | 0.00% |
| Tower Research Capital LLC (TRC) | 11,427 | $8.98K | 0.00% |
| Group One Trading, L.P. | 3,939 | $3.10K | 0.00% |
| FMR LLC | 103 | $81 | 0.00% |
| Macquarie Group Ltd | 362 | $0 | 0.00% |
Sold out (12)
Institutions that held Spruce Biosciences, Inc. at the end of Q4 2023 and filed for Q1 2024 without it.
| Institution | Shares, Q4 2023 | Value, Q4 2023 |
|---|---|---|
| Novo Holdings A/S | 6,722,336 | $19.7M |
| 5AM Venture Management, LLC | 2,364,000 | $6.93M |
| Armistice Capital, LLC | 2,230,000 | $6.53M |
| Omega Fund Management, LLC | 2,161,022 | $6.33M |
| AIGH Capital Management LLC | 2,123,863 | $6.22M |
| DAFNA Capital Management LLC | 548,510 | $1.61M |
| Worth Venture Partners, LLC | 526,933 | $1.54M |
| Alyeska Investment Group, L.P. | 400,000 | $1.17M |
| Acuitas Investments, LLC | 275,085 | $806.0K |
| Marquette Asset Management, LLC | 55,757 | $163.4K |
| Sofinnova Investments, Inc. | 22,767 | $66.7K |
| Royal Bank of Canada | 8,907 | $26.0K |