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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

Q1 2023 vs. Q4 2022

How the institutions holding Spruce Biosciences, Inc. changed between Q4 2022 and Q1 2023.

All holders in Q1 2023All holders in Q4 2022

13F holders of SPRB: Q4 2022 compared with Q1 2023
MeasureQ4 2022Of which not filed for Q1 2023Q1 2023Change
Holders31144+14
Shares18.2M1.79M33.8M+17.3M (+105.2%)
Value$20.0M$1.97M$74.5M+$56.5M (+313.6%)

1 institution that held it in Q4 2022 haven't filed for Q1 2023 yet. Not filing isn't selling, so the changes leave them out.

New holders (16)

Institutions that held Spruce Biosciences, Inc. at the end of Q1 2023 but not at the end of Q4 2022.

Institutions new to SPRB in Q1 2023
InstitutionSharesValue% of portfolio
Armistice Capital, LLC3,928,000$8.68M0.20%
Carlyle Group Inc.2,896,518$6.40M0.19%
5AM Venture Management, LLC2,364,000$5.22M1.34%
AIGH Capital Management LLC1,104,000$2.37M0.88%
Alyeska Investment Group, L.P.1,000,000$2.21M0.02%
Verition Fund Management LLC961,899$2.13M0.03%
CVI Holdings, LLC472,000$1.04M0.39%
DAFNA Capital Management LLC312,000$689.5K0.21%
Worth Venture Partners, LLC270,624$581.5K0.29%
Goldman Sachs Group Inc182,656$403.7K0.00%
Two Sigma Investments, LP163,165$360.6K0.00%
Royal Bank of Canada93,920$208.0K0.00%
Two Sigma Advisers, LP37,600$83.1K0.00%
Virtu Financial LLC13,722$30.0K0.00%
HRT Financial LP13,340$29.0K0.00%
FMR LLC50$1110.00%

Sold out (2)

Institutions that held Spruce Biosciences, Inc. at the end of Q4 2022 and filed for Q1 2023 without it.

Institutions that sold out of SPRB in Q1 2023
InstitutionShares, Q4 2022Value, Q4 2022
Logos Global Management LP1,000,000$1.10M
BML Capital Management, LLC221,830$243.4K

Not filed for Q1 2023 yet (1)

Institutions that held Spruce Biosciences, Inc. at the end of Q4 2022 and haven't filed a 13F for Q1 2023. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding SPRB in Q4 2022 that haven't filed for Q1 2023
InstitutionShares, Q4 2022Value, Q4 2022
Abingworth LLP1,792,518$1.97M