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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

Q1 2022 vs. Q4 2021

How the institutions holding Spruce Biosciences, Inc. changed between Q4 2021 and Q1 2022.

All holders in Q1 2022All holders in Q4 2021

13F holders of SPRB: Q4 2021 compared with Q1 2022
MeasureQ4 2021Q1 2022Change
Holders5043−7
Shares17.7M17.1M−619.8K (−3.5%)
Value$79.0M$34.4M−$44.6M (−56.5%)

New holders (4)

Institutions that held Spruce Biosciences, Inc. at the end of Q1 2022 but not at the end of Q4 2021.

Institutions new to SPRB in Q1 2022
InstitutionSharesValue% of portfolio
Barclays PLC12,691$25.0K0.00%
Point72 Hong Kong Ltd2,881$6.00K0.00%
Amalgamated Bank1,084$2.00K0.00%
Amalgamated Financial Corp.1,084$2.00K0.00%

Sold out (11)

Institutions that held Spruce Biosciences, Inc. at the end of Q4 2021 and filed for Q1 2022 without it.

Institutions that sold out of SPRB in Q1 2022
InstitutionShares, Q4 2021Value, Q4 2021
Acadian Asset Management LLC71,756$318.0K
Jane Street Group, LLC35,953$160.0K
Bank of Montreal26,259$132.0K
Two Sigma Securities, LLC28,691$128.0K
Susquehanna International Group, LLP27,306$122.0K
Prelude Capital Management, LLC16,718$75.0K
Squarepoint Ops LLC13,593$61.0K
Laurion Capital Management LP11,337$51.0K
Captrust Financial Advisors1,477$7.00K
Capital Advisors, Ltd. LLC242$1.00K
Ellevest, Inc.114$1.00K