Spruce Biosciences, Inc.
SPRB- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001683553
No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.
Q4 2021 vs. Q3 2021
How the institutions holding Spruce Biosciences, Inc. changed between Q3 2021 and Q4 2021.
All holders in Q4 2021All holders in Q3 2021
| Measure | Q3 2021 | Q4 2021 | Change |
|---|---|---|---|
| Holders | 44 | 50 | +6 |
| Shares | 19.6M | 17.7M | −1.93M (−9.8%) |
| Value | $118.1M | $79.0M | −$39.1M (−33.1%) |
New holders (16)
Institutions that held Spruce Biosciences, Inc. at the end of Q4 2021 but not at the end of Q3 2021.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| Logos Global Management LP | 1,100,000 | $4.91M | 0.51% |
| Bridgeway Capital Management, LLC | 209,864 | $936.0K | 0.02% |
| Acadian Asset Management LLC | 71,756 | $318.0K | 0.00% |
| Parametric Portfolio Associates LLC | 64,628 | $288.0K | 0.00% |
| Marquette Asset Management, LLC | 40,853 | $182.0K | 0.04% |
| Cubist Systematic Strategies, LLC | 40,589 | $181.0K | 0.00% |
| Jane Street Group, LLC | 35,953 | $160.0K | 0.00% |
| Bank of Montreal | 26,259 | $132.0K | 0.00% |
| Two Sigma Securities, LLC | 28,691 | $128.0K | 0.02% |
| Susquehanna International Group, LLP | 27,306 | $122.0K | 0.00% |
| Prelude Capital Management, LLC | 16,718 | $75.0K | 0.00% |
| Squarepoint Ops LLC | 13,593 | $61.0K | 0.00% |
| UBS Group AG | 5,349 | $24.0K | 0.00% |
| Captrust Financial Advisors | 1,477 | $7.00K | 0.00% |
| TCI Wealth Advisors, Inc. | 250 | $1.00K | 0.00% |
| Capital Advisors, Ltd. LLC | 242 | $1.00K | 0.00% |
Sold out (10)
Institutions that held Spruce Biosciences, Inc. at the end of Q3 2021 and filed for Q4 2021 without it.
| Institution | Shares, Q3 2021 | Value, Q3 2021 |
|---|---|---|
| Deerfield Management Company, L.P. (Series C) | 2,200,000 | $13.2M |
| Sio Capital Management, LLC | 603,027 | $3.62M |
| Granite Point Capital Management, L.P. | 63,614 | $382.0K |
| Millennium Management LLC | 38,622 | $232.0K |
| Two Sigma Investments, LP | 29,392 | $177.0K |
| Alps Advisors Inc | 28,648 | $172.0K |
| Caas Capital Management LP | 27,546 | $166.0K |
| Jacobs Levy Equity Management, Inc | 24,361 | $146.0K |
| Two Sigma Advisers, LP | 19,200 | $115.0K |
| Trexquant Investment LP | 11,998 | $72.0K |