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Spruce Biosciences, Inc.

SPRB
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001683553

No open-market purchases or sales by Spruce Biosciences, Inc. insiders were filed in the last 90 days; 65 institutions reported holding it in 13F filings for Q2 2026, worth $116.3M in total; no superinvestor holds it.

Q3 2021 vs. Q2 2021

How the institutions holding Spruce Biosciences, Inc. changed between Q2 2021 and Q3 2021.

All holders in Q3 2021All holders in Q2 2021

13F holders of SPRB: Q2 2021 compared with Q3 2021
MeasureQ2 2021Q3 2021Change
Holders4144+3
Shares20.1M19.6M−456.3K (−2.3%)
Value$225.3M$118.1M−$107.2M (−47.6%)

New holders (7)

Institutions that held Spruce Biosciences, Inc. at the end of Q3 2021 but not at the end of Q2 2021.

Institutions new to SPRB in Q3 2021
InstitutionSharesValue% of portfolio
Sands Capital Ventures, LLC787,007$4.73M0.71%
Renaissance Technologies LLC34,000$204.0K0.00%
Jacobs Levy Equity Management, Inc24,361$146.0K0.00%
Two Sigma Advisers, LP19,200$115.0K0.00%
State Board of Administration of Florida Retirement System17,440$105.0K0.00%
Trexquant Investment LP11,998$72.0K0.01%
Ellevest, Inc.31$00.00%

Sold out (4)

Institutions that held Spruce Biosciences, Inc. at the end of Q2 2021 and filed for Q3 2021 without it.

Institutions that sold out of SPRB in Q3 2021
InstitutionShares, Q2 2021Value, Q2 2021
Sands Capital Management, LLC787,007$8.82M
Adage Capital Partners GP, L.L.C.240,511$2.70M
Alyeska Investment Group, L.P.19,413$218.0K
STRS Ohio2,400$26.0K