| Jul 9, 2026 (view filing)4:54 PM ET | Jul 8 | 1 day | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −32.4K | $24.24 | −$784.8K | −6.3%484.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 12, 2026 (view filing) | Jun 11-12 | 1 day | Botwood Nicholas A.J.Head of R&D, CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −65.5K | $18.07 | −$1.18M | −51.8%60.9K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 2, 2026 (view filing) | Jun 1 | 1 day | Goldan Keith A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.18K | $18.99 | −$22.4K | −0.8%139.3K after | |
| Jun 2, 2026 (view filing) | Jun 1 | 1 day | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −6.85K | $18.99 | −$130.0K | −1.4%484.8K after | |
| Feb 10, 2026 (view filing) | Feb 9 | 1 day | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.2K | $21.03 | −$360.9K | −3.4%491.7K after | |
| Feb 10, 2026 (view filing) | Feb 9 | 1 day | Goldan Keith A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.41K | $21.03 | −$71.7K | −2.4%140.4K after | |
| Feb 6, 2026 (view filing) | Feb 6 | Same day | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.41K | $20.62 | −$152.8K | −1.4%508.8K after | |
| Feb 6, 2026 (view filing) | Feb 6 | Same day | Goldan Keith A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −2.08K | $20.62 | −$42.9K | −1.4%143.8K after | |
| Sep 8, 2025 (view filing) | Sep 8 | Same day | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −157.3K | $16.41 | −$2.58M | −34.5%298.7K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 18, 2025 (view filing) | Aug 14-18 | 4 days | Podlesak DennisDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −57.6K | $15.19 | −$874.9K | −23.1%191.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 18, 2025 (view filing) | Jul 16 | 2 days | Goldan Keith A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.30K | $9.29 | −$12.0K | −1.4%92.5K after | |
| Jul 18, 2025 (view filing) | Jul 16 | 2 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.53K | $9.29 | −$70.0K | −2.5%298.7K after | |
| May 19, 2025 (view filing) | May 19 | Same day | Goldan Keith A.Chief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +3.00K | – | – | +3.3%93.7K after | |
| May 19, 2025 (view filing) | May 16 | 3 days | Botwood Nicholas A.J.Head of R&D, CMO | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +11.8K | $9.00 | +$105.9K | +50.3%35.2K after | |
| May 19, 2025 (view filing) | May 19 | Same day | Huber Martin H. Jr.Director | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +5.00K | $8.99 | +$45.0K | +6.8%79.0K after | |
| May 19, 2025 (view filing) | May 19 | Same day | Katkin KeithDirector | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +10.0K | $9.11 | +$91.1K | +11.1%100.0K after | |
| Mar 6, 2025 (view filing) | Mar 4 | 2 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.81K | $15.05 | −$117.6K | −2.5%300.1K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Goldan Keith A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.78K | $15.50 | −$58.5K | −4.0%90.7K after | |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −13.3K | $15.50 | −$206.0K | −4.2%300.1K after | |
| Feb 12, 2025 (view filing) | Feb 10 | 2 days | Gallagher NeilPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.62K | $15.50 | −$71.6K | −5.1%85.1K after | |
| Jun 17, 2024 (view filing) | Jun 14 | 3 days | Goldan Keith A.Chief Financial Officer | PPurchaseThe insider bought shares with their own money, on the open market or in a private deal (for example, a company's private placement). This is the code investors watch most closely: it is money the insider chose to put in. | +1.25K | $20.03 | +$25.0K | +2.4%52.6K after | |
| Aug 10, 2023 (view filing) | Aug 9 | 1 day | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $18.27 | −$965.7K | −74.8%17.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Aug 3, 2023 (view filing) | Aug 2 | 1 day | Meury WilliamDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −83.0K | $20.46 | −$1.70M | −63.4%48.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jul 11, 2023 (view filing) | Jul 10 | 1 day | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $20.40 | −$1.08M | −74.8%17.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Jun 14, 2023 (view filing) | Jun 13 | 1 day | Goldan Keith A.Chief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −577 | $22.31 | −$12.9K | −18.0%2.63K after | |
| Jun 9, 2023 (view filing) | Jun 9 | Same day | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $21.18 | −$1.12M | −74.8%17.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average.10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| May 10, 2023 (view filing) | May 9 | 1 day | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $21.41 | −$1.13M | −74.8%17.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Apr 12, 2023 (view filing) | Apr 10 | 2 days | Morrison BriggsDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $19.53 | −$1.03M | −74.8%17.8K after | 10b5-1The filer checked the Rule 10b5-1 box: this trade was made under a trading plan set up in advance. |
| Mar 14, 2023 (view filing) | Mar 13 | 1 day | Morrison BriggsPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $22.53 | −$1.19M | −74.8%17.8K after | |
| Feb 17, 2023 (view filing) | Feb 15 | 2 days | Ordentlich PeterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $25.84 | −$646.0K | −100.0%0 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 8, 2023 (view filing) | Feb 6 | 2 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.96K | $27.64 | −$164.7K | −25.2%17.7K after | |
| Feb 8, 2023 (view filing) | Feb 6 | 2 days | Morrison BriggsPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −52.9K | $26.83 | −$1.42M | −74.8%17.8K after | |
| Feb 3, 2023 (view filing) | Feb 1 | 2 days | Ordentlich PeterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −69 | $28.43 | −$1.96K | −100.0%0 after | |
| Jan 13, 2023 (view filing) | Jan 12-13 | 1 day | Legault PierreDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −39.0K | $26.84 | −$1.05M | −54.9%32.0K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 2, 2022 (view filing) | Dec 1-2 | 1 day | Ordentlich PeterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $25.04 | −$625.9K | −99.0%265 after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 7, 2022 (view filing) | Oct 6 | 1 day | Katkin KeithDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −29.9K | $25.90 | −$774.4K | −48.3%32.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 7, 2022 (view filing) | Oct 6 | 1 day | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −16.2K | $25.29 | −$410.5K | −47.9%17.7K after | |
| Oct 4, 2022 (view filing) | Sep 30-Oct 4 | 4 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −33.8K | $25.02 | −$844.9K | −65.7%17.7K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Oct 4, 2022 (view filing) | Sep 30-Oct 4 | 4 days | Katkin KeithDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.10K | $25.06 | −$102.8K | −11.4%32.0K after | 6 lotsThis row combines 6 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 21, 2022 (view filing) | Sep 19-20 | 2 days | Morrison BriggsPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −174.0K | $23.11 | −$4.02M | −90.7%17.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 16, 2022 (view filing) | Sep 14-16 | 2 days | Morrison BriggsPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −279.4K | $23.64 | −$6.60M | −94.0%17.8K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 16, 2022 (view filing) | Sep 15-16 | 1 day | Podlesak DennisDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −78.8K | $24.08 | −$1.90M | −51.0%75.8K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 26, 2022 (view filing) | Aug 24 | 2 days | Ordentlich PeterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −25.0K | $25.04 | −$626.0K | −99.0%265 after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 9, 2022 (view filing) | Aug 5 | 4 days | Legault PierreDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −24.0K | $23.02 | −$552.5K | −42.9%32.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 27, 2022 (view filing) | Jul 25 | 2 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −31.6K | $21.06 | −$665.5K | −64.2%17.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 8, 2022 (view filing) | Jul 6-7 | 2 days | Metzger Michael AChief Executive Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −15.1K | $21.07 | −$318.3K | −46.1%17.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 5, 2022 (view filing) | Jul 1 | 4 days | Morrison BriggsPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −62.3K | $19.00 | −$1.18M | −77.7%17.8K after | |
| Apr 5, 2022 (view filing) | Apr 1-4 | 4 days | Morrison BriggsPresident, Head of R&D | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −104.2K | $17.48 | −$1.82M | −85.4%17.8K after | AmendedAn amended filing (for example Form 4/A or 13F-HR/A) that corrects or adds to an earlier filing.4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 3, 2022 (view filing) | Feb 1 | 2 days | Ordentlich PeterChief Scientific Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.41K | $16.65 | −$23.5K | −100.0%0 after | |
| Feb 3, 2022 (view filing) | Feb 1 | 2 days | Nolte AlexanderChief Accounting Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −968 | $16.65 | −$16.1K | −100.0%0 after | |
