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ACELYRIN, Inc.

SLRNDelisted May 21, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001962918

ACELYRIN, Inc. was delisted on May 21, 2025; its insiders filed their last Form 4 on May 23, 2025; 106 institutions reported holding it in 13F filings for Q1 2025, worth $182.6M in total; no superinvestor held it.

13F holders, Q4 2024

Institutional positions in ACELYRIN, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
126
+5 vs. Q3 2024
Shares held
88.0M
+766.9K (+0.9%) vs. Q3 2024
Total value
$276.4M
−$153.6M (−35.7%) vs. Q3 2024
New holders
19
44 more added
Sold out
14
40 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLRN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 126 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 82 institutionsQ3 2023: 102 institutionsQ4 2023: 110 institutionsQ1 2024: 109 institutionsQ2 2024: 113 institutionsQ3 2024: 122 institutionsQ4 2024: 126 institutionsQ1 2025: 106 institutionsQ2 2025: 2 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2024: $276.4M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $1.60BQ3 2023: $847.0MQ4 2023: $632.6MQ1 2024: $613.2MQ2 2024: $383.7MQ3 2024: $430.2MQ4 2024: $276.4MQ1 2025: $182.6MQ2 2025: $704Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SLRN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20252$704
Q1 2025106$182.6M
Q4 2024126$276.4M
Q3 2024122$430.2M
Q2 2024113$383.7M
Q1 2024109$613.2M
Q4 2023110$632.6M
Q3 2023102$847.0M
Q2 202382$1.60B
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding ACELYRIN, Inc.; share changes are against Q3 2024.

Institutions holding SLRN in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
T. Rowe Price Investment Management, Inc.12,872,124$40.4M0.02%+2,440,278+23.4%Added
AyurMaya Capital Management Company, LP9,334,735$29.3M25.94%00.0%Unchanged
BlackRock, Inc.6,020,868$18.9M0.00%+38,494+0.6%Added
Millennium Management LLC4,714,402$14.8M0.01%−772,770−14.1%Reduced
Citadel Advisors LLC4,211,916$13.2M0.01%−2,311,390−35.4%Reduced
Vanguard Group Inc4,080,010$12.8M0.00%+13,021+0.3%Added
OrbiMed Advisors LLC4,001,711$12.6M0.26%00.0%Unchanged
venBio Partners LLC3,806,410$12.0M7.00%−46,060−1.2%Reduced
Tybourne Capital Management (HK) Ltd2,906,629$9.13M2.29%00.0%Unchanged
Blue Owl Capital Holdings LP2,783,946$8.74M2.07%−10,000−0.4%Reduced
General Atlantic LLC2,695,327$8.46M0.30%−194,341−6.7%Reduced
Samsara BioCapital, LLC2,523,022$7.92M1.09%00.0%Unchanged
Morgan Stanley2,323,521$7.30M0.00%+537,068+30.1%Added
Opaleye Management Inc.2,235,000$7.17M1.26%+341,340+18.0%Added
Palo Alto Investors LP1,792,895$5.63M0.87%00.0%Unchanged
Siren, L.L.C.1,729,665$5.43M0.24%00.0%Unchanged
Geode Capital Management, LLC1,709,086$5.37M0.00%+57,472+3.5%Added
StemPoint Capital LP1,704,825$5.35M1.34%+386,971+29.4%Added
Alyeska Investment Group, L.P.1,515,878$4.76M0.02%+1,515,878New
State Street Corp1,441,273$4.53M0.00%+168,177+13.2%Added
RTW Investments, LP978,310$3.07M0.05%00.0%Unchanged
Kynam Capital Management, LP847,366$2.66M0.18%00.0%Unchanged
Ikarian Capital, LLC676,608$2.12M0.61%−466−0.1%Reduced
Jacobs Levy Equity Management, Inc662,981$2.08M0.01%−663,410−50.0%Reduced
Northern Trust Corp630,051$1.98M0.00%+23,130+3.8%Added
JPMorgan Chase & Co618,127$1.94M0.00%−232,534−27.3%Reduced
Charles Schwab Investment Management Inc614,474$1.93M0.00%+4,796+0.8%Added
Marshall Wace, LLP572,048$1.80M0.00%00.0%Unchanged
Goldman Sachs Group Inc569,910$1.79M0.00%+47,988+9.2%Added
Renaissance Technologies LLC466,921$1.47M0.00%−67,897−12.7%Reduced
Adage Capital Partners GP, L.L.C.450,000$1.41M0.00%−95,476−17.5%Reduced
Kennedy Capital Management, Inc.446,850$1.40M0.03%−5,920−1.3%Reduced
ADAR1 Capital Management, LLC444,967$1.40M0.29%+391,467+731.7%Added
TD Asset Management Inc267,656$840.4K0.00%+93,276+53.5%Added
Susquehanna Fundamental Investments, LLC237,465$745.6K0.01%+237,465New
Exome Asset Management LLC234,435$736.1K0.55%+234,435New
Ameriprise Financial Inc228,098$716.2K0.00%−8,564−3.6%Reduced
UBS Oconnor LLC211,938$665.5K0.02%+48,214+29.4%Added
Nuveen Asset Management, LLC202,239$635.0K0.00%00.0%Unchanged
Bank of America Corp197,835$621.2K0.00%+19,165+10.7%Added
Hudson Bay Capital Management LP196,620$617.4K0.00%−3,380−1.7%Reduced
UBS Group AG187,005$587.2K0.00%+148,199+381.9%Added
Wellington Management Group LLP180,539$566.9K0.00%+180,539New
Bank of New York Mellon Corp176,899$555.5K0.00%+684+0.4%Added
FMR LLC164,311$515.9K0.00%+46,563+39.5%Added
Almitas Capital LLC148,704$466.9K0.10%+124,185+506.5%Added
Blair William & Co138,595$435.2K0.00%00.0%Unchanged
ExodusPoint Capital Management, LP134,680$423.0K0.00%+134,680New
Stonepine Capital Management, LLC132,870$417.2K0.34%+132,870New
Los Angeles Capital Management LLC122,003$383.1K0.00%−20,690−14.5%Reduced
Dimensional Fund Advisors LP118,241$371.3K0.00%+118,241New
Barclays PLC116,644$366.3K0.00%+20,236+21.0%Added
Rhumbline Advisers108,243$339.9K0.00%+1,862+1.8%Added
Martingale Asset Management L P102,596$322.2K0.01%+4,312+4.4%Added
Acadian Asset Management LLC101,514$318.0K0.00%−91,203−47.3%Reduced
Public Employees Retirement System of Ohio97,347$305.7K0.00%−5,000−4.9%Reduced
Franklin Resources Inc90,554$284.3K0.00%−38,037−29.6%Reduced
Prelude Capital Management, LLC88,181$276.9K0.02%+58,755+199.7%Added
DAFNA Capital Management LLC87,989$276.3K0.07%−514,905−85.4%Reduced
Alps Advisors Inc81,129$254.7K0.00%+3,883+5.0%Added
American Century Companies Inc78,868$247.6K0.00%+46,802+146.0%Added
Algert Global LLC77,060$242.0K0.01%+12,230+18.9%Added
BNP Paribas Arbitrage, SA75,114$235.9K0.00%+75,114New
Alliancebernstein L.P.73,670$231.3K0.00%00.0%Unchanged
Deutsche Bank AG70,000$219.8K0.00%+24,356+53.4%Added
Russell Investments Group, Ltd.66,699$209.4K0.00%−9,341−12.3%Reduced
Citigroup Inc57,911$181.8K0.00%+2,979+5.4%Added
Wells Fargo & Company52,014$163.3K0.00%+9,332+21.9%Added
Tudor Investment Corp Et Al48,299$151.7K0.00%−92−0.2%Reduced
STRS Ohio44,300$139.1K0.00%00.0%Unchanged
MetLife Investment Management42,852$134.6K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.41,908$131.6K0.00%+1,824+4.6%Added
Corebridge Financial, Inc.36,288$113.9K0.00%−2,740−7.0%Reduced
Virtus Investment Advisers, Inc.35,700$112.1K0.09%00.0%Unchanged
Susquehanna International Group, LLP34,824$109.3K0.00%+6,688+23.8%Added
SG Americas Securities, LLC30,488$96.0K0.00%+3,733+14.0%Added
Boothbay Fund Management, LLC29,828$93.7K0.00%+10,554+54.8%Added
Manufacturers Life Insurance Company, The28,104$88.2K0.00%−701−2.4%Reduced
Verition Fund Management LLC27,480$86.3K0.00%−82,635−75.0%Reduced
Thrivent Financial for Lutherans26,604$84.0K0.00%−10,737−28.8%Reduced
Price T Rowe Associates Inc26,738$84.0K0.00%+3,266+13.9%Added
Intech Investment Management LLC26,587$83.5K0.00%+11,040+71.0%Added
Invesco Ltd.25,766$80.9K0.00%+2,777+12.1%Added
ProShare Advisors LLC25,307$79.5K0.00%+5,617+28.5%Added
Royal Bank of Canada22,528$71.0K0.00%+14,028+165.0%Added
Voya Investment Management LLC22,282$70.0K0.00%−2,741−11.0%Reduced
PDT Partners, LLC21,860$68.6K0.01%−58,684−72.9%Reduced
China Universal Asset Management Co., Ltd.21,273$66.8K0.01%+2,077+10.8%Added
Virtus ETF Advisers LLC20,083$63.1K0.03%−1,055−5.0%Reduced
Two Sigma Advisers, LP16,700$52.4K0.00%−65,400−79.7%Reduced
HRT Financial LP16,021$50.0K0.00%−78,784−83.1%Reduced
New York State Common Retirement Fund15,512$48.7K0.00%−7,305−32.0%Reduced
Man Group plc15,193$47.7K0.00%+1,578+11.6%Added
Police & Firemen's Retirement System of New Jersey14,886$46.7K0.00%+14,886New
Rpo LLC14,693$46.1K0.06%+14,693New
Bank of Montreal14,532$45.6K0.00%−134,103−90.2%Reduced
Prudential Financial Inc14,130$44.4K0.00%−62,600−81.6%Reduced
Ausdal Financial Partners, Inc.12,800$40.2K0.00%−6,500−33.7%Reduced
HSBC Holdings PLC11,663$36.3K0.00%+11,663New
4WEALTH Advisors, Inc.11,212$35.2K0.04%+11,212New