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ACELYRIN, Inc.

SLRNDelisted
Industry
Pharmaceutical Preparations
SEC CIK
0001962918

ACELYRIN, Inc. was delisted in 2025; its insiders filed their last Form 4 on May 23, 2025; 106 institutions reported holding it in 13F filings for Q1 2025, worth $182.7M in total; no superinvestor held it.

13F holders, Q1 2025

Institutional positions in ACELYRIN, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

SLRN is no longer listed, so this page shows Q1 2025. 13F filings for later quarters list far fewer holders.

Institutional holders
106
−19 vs. Q4 2024
Shares held
73.9M
−13.8M (−15.8%) vs. Q4 2024
Total value
$182.7M
−$93.1M (−33.8%) vs. Q4 2024
New holders
23
23 more added
Sold out
42
40 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLRN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 106 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 82 institutionsQ3 2023: 102 institutionsQ4 2023: 110 institutionsQ1 2024: 109 institutionsQ2 2024: 113 institutionsQ3 2024: 122 institutionsQ4 2024: 126 institutionsQ1 2025: 106 institutionsQ2 2025: 2 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ1 2025: $182.7M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $1.60BQ3 2023: $847.0MQ4 2023: $663.0MQ1 2024: $639.7MQ2 2024: $395.2MQ3 2024: $434.4MQ4 2024: $276.4MQ1 2025: $182.7MQ2 2025: $704Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SLRN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20252$704
Q1 2025106$182.7M
Q4 2024126$276.4M
Q3 2024122$434.4M
Q2 2024113$395.2M
Q1 2024109$639.7M
Q4 2023110$663.0M
Q3 2023102$847.0M
Q2 202382$1.60B
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding ACELYRIN, Inc.; share changes are against Q4 2024.

Institutions holding SLRN in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Tang Capital Management LLC9,818,115$24.3M1.34%+9,818,115New
AyurMaya Capital Management Company, LP9,334,735$23.1M26.08%00.0%Unchanged
BlackRock, Inc.5,805,096$14.3M0.00%−215,772−3.6%Reduced
T. Rowe Price Investment Management, Inc.4,649,865$11.5M0.01%−8,222,259−63.9%Reduced
Madison Avenue Partners, LP4,142,640$10.2M0.87%+4,142,640New
Vanguard Group Inc4,079,706$10.1M0.00%−3040.0%Reduced
OrbiMed Advisors LLC4,001,711$9.88M0.24%00.0%Unchanged
venBio Partners LLC3,806,410$9.40M7.61%00.0%Unchanged
Velan Capital Investment Management LP3,366,945$8.32M8.56%+3,366,945New
Tybourne Capital Management (HK) Ltd2,906,629$7.18M30.48%00.0%Unchanged
General Atlantic LLC2,695,327$6.66M0.22%00.0%Unchanged
Samsara BioCapital, LLC2,523,022$6.23M1.11%00.0%Unchanged
Palo Alto Investors LP1,792,895$4.43M0.84%00.0%Unchanged
Geode Capital Management, LLC1,773,818$4.38M0.00%+64,732+3.8%Added
Opaleye Management Inc.1,615,000$3.99M0.89%−620,000−27.7%Reduced
State Street Corp1,420,068$3.51M0.00%−21,205−1.5%Reduced
Balyasny Asset Management LLC1,305,015$3.22M0.01%+1,305,015New
Alyeska Investment Group, L.P.615,878$1.52M0.01%−900,000−59.4%Reduced
Renaissance Technologies LLC599,800$1.48M0.00%+132,879+28.5%Added
Northern Trust Corp598,151$1.48M0.00%−31,900−5.1%Reduced
JPMorgan Chase & Co590,846$1.46M0.00%−27,281−4.4%Reduced
Cantor Fitzgerald, L. P.588,664$1.45M0.05%+588,664New
Charles Schwab Investment Management Inc544,575$1.35M0.00%−69,899−11.4%Reduced
Towerview LLC540,000$1.33M0.96%+540,000New
Goldman Sachs Group Inc351,407$868.0K0.00%−218,503−38.3%Reduced
Morgan Stanley275,815$681.3K0.00%−2,047,706−88.1%Reduced
Susquehanna Fundamental Investments, LLC273,412$675.3K0.01%+35,947+15.1%Added
Nuveen, LLC202,239$499.5K0.00%+202,239New
AQR Capital Management LLC193,323$477.5K0.00%+193,323New
Wellington Management Group LLP179,150$442.5K0.00%−1,389−0.8%Reduced
Citadel Advisors LLC176,437$435.8K0.00%−4,035,479−95.8%Reduced
Bank of New York Mellon Corp173,277$428.0K0.00%−3,622−2.0%Reduced
Stonepine Capital Management, LLC167,580$413.9K0.40%+34,710+26.1%Added
Millennium Management LLC149,298$368.8K0.00%−4,565,104−96.8%Reduced
Bridgeway Capital Management, LLC140,900$348.0K0.01%+140,900New
Monaco Asset Management SAM139,600$344.8K0.17%+139,600New
Blair William & Co138,595$342.3K0.00%00.0%Unchanged
Franklin Resources Inc127,023$313.7K0.00%+36,469+40.3%Added
Los Angeles Capital Management LLC109,612$270.7K0.00%−12,391−10.2%Reduced
UBS Group AG103,525$255.7K0.00%−83,480−44.6%Reduced
XTX Topco Ltd103,047$254.5K0.01%+92,678+893.8%Added
Rhumbline Advisers102,174$252.4K0.00%−6,069−5.6%Reduced
American Century Companies Inc91,390$225.7K0.00%+12,522+15.9%Added
Susquehanna International Group, LLP90,669$224.0K0.00%+55,845+160.4%Added
Invesco Ltd.85,520$211.2K0.00%+59,754+231.9%Added
Barclays PLC82,871$204.7K0.00%−33,773−29.0%Reduced
Alps Advisors Inc74,640$184.4K0.00%−6,489−8.0%Reduced
Alliancebernstein L.P.73,670$182.0K0.00%00.0%Unchanged
HGC Investment Management Inc.70,425$173.9K0.06%+70,425New
Deutsche Bank AG61,539$152.0K0.00%−8,461−12.1%Reduced
Citigroup Inc53,629$132.5K0.00%−4,282−7.4%Reduced
Marshall Wace, LLP53,100$131.2K0.00%−518,948−90.7%Reduced
Wells Fargo & Company52,608$129.9K0.00%+594+1.1%Added
LMR Partners LLP50,000$123.5K0.00%+50,000New
Intech Investment Management LLC49,830$123.1K0.00%+23,243+87.4%Added
Yakira Capital Management, Inc.48,557$119.9K0.05%+48,557New
Virtus Investment Advisers, Inc.46,372$114.5K0.03%+10,672+29.9%Added
Dimensional Fund Advisors LP44,755$110.5K0.00%−73,486−62.1%Reduced
STRS Ohio44,300$109.4K0.00%00.0%Unchanged
Mirae Asset Global ETFs Holdings Ltd.43,780$108.1K0.00%+1,872+4.5%Added
Voya Investment Management LLC41,536$102.6K0.00%+19,254+86.4%Added
Bank of America Corp36,410$89.9K0.00%−161,425−81.6%Reduced
Corebridge Financial, Inc.36,269$89.6K0.00%−19−0.1%Reduced
Prelude Capital Management, LLC36,220$89.5K0.01%−51,961−58.9%Reduced
Price T Rowe Associates Inc34,515$86.0K0.00%+7,777+29.1%Added
Mariner, LLC31,389$77.5K0.00%+31,389New
Manufacturers Life Insurance Company, The28,717$70.9K0.00%+613+2.2%Added
SG Americas Securities, LLC27,110$67.0K0.00%−3,378−11.1%Reduced
Western Wealth Management, LLC25,000$61.8K0.00%+25,000New
CSS LLC24,564$60.7K0.00%+24,564New
ProShare Advisors LLC20,570$50.8K0.00%−4,737−18.7%Reduced
China Universal Asset Management Co., Ltd.20,199$49.9K0.00%−1,074−5.0%Reduced
MetLife Investment Management18,493$45.7K0.00%−24,359−56.8%Reduced
Nisa Investment Advisors, LLC16,586$41.0K0.00%+16,503+19,883.1%Added
CIBC World Markets Corp16,427$40.6K0.00%+16,427New
New York State Common Retirement Fund15,512$38.3K0.00%00.0%Unchanged
Bank of Montreal15,227$37.6K0.00%+695+4.8%Added
Two Sigma Advisers, LP15,100$37.3K0.00%−1,600−9.6%Reduced
Police & Firemen's Retirement System of New Jersey14,886$36.8K0.00%00.0%Unchanged
CWM, LLC13,090$32.0K0.00%+12,933+8,237.6%Added
Ausdal Financial Partners, Inc.12,800$31.6K0.00%00.0%Unchanged
SEI Investments Co10,782$26.6K0.00%00.0%Unchanged
Cerity Partners LLC10,419$25.7K0.00%+10,419New
Quadrature Capital Ltd10,246$25.3K0.00%+10,246New
HighTower Advisors, LLC10,031$24.8K0.00%−155−1.5%Reduced
FNY Investment Advisers, LLC10,000$24.0K0.01%+10,000New
Group One Trading, L.P.7,662$18.9K0.00%+5,117+201.1%Added
Ameritas Investment Partners, Inc.7,243$17.9K0.00%00.0%Unchanged
Legal & General Group Plc6,625$16.3K0.00%00.0%Unchanged
California State Teachers Retirement System5,289$13.1K0.00%00.0%Unchanged
Royal Bank of Canada5,263$13.0K0.00%−17,265−76.6%Reduced
BNP Paribas Arbitrage, SA5,061$12.5K0.00%−70,053−93.3%Reduced
FMR LLC4,976$12.3K0.00%−159,335−97.0%Reduced
Tower Research Capital LLC (TRC)3,637$8.98K0.00%−3,260−47.3%Reduced
Mirae Asset Global Investments Co., Ltd.3,370$8.76K0.00%+27+0.8%Added
GF Fund Management Co. Ltd.2,569$6.34K0.00%+462+21.9%Added
Amalgamated Bank2,452$6.00K0.00%00.0%Unchanged
Sterling Capital Management LLC1,311$3.24K0.00%−1,028−44.0%Reduced
Caitong International Asset Management Co., Ltd1,279$3.16K0.00%+1,279New
Daiwa Securities Group Inc.398$1.00K0.00%00.0%Unchanged