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ACELYRIN, Inc.

SLRNDelisted May 21, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001962918

ACELYRIN, Inc. was delisted on May 21, 2025; its insiders filed their last Form 4 on May 23, 2025; 106 institutions reported holding it in 13F filings for Q1 2025, worth $182.6M in total; no superinvestor held it.

13F holders, Q4 2023

Institutional positions in ACELYRIN, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
110
+10 vs. Q3 2023
Shares held
84.8M
+4.81M (+6.0%) vs. Q3 2023
Total value
$632.6M
−$175.7M (−21.7%) vs. Q3 2023
New holders
35
31 more added
Sold out
25
28 more reduced

2 institutions that held it in Q3 2023 haven't filed for Q4 2023 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLRN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 110 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 82 institutionsQ3 2023: 102 institutionsQ4 2023: 110 institutionsQ1 2024: 109 institutionsQ2 2024: 113 institutionsQ3 2024: 122 institutionsQ4 2024: 126 institutionsQ1 2025: 106 institutionsQ2 2025: 2 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2023: $632.6M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $1.60BQ3 2023: $847.0MQ4 2023: $632.6MQ1 2024: $613.2MQ2 2024: $383.7MQ3 2024: $430.2MQ4 2024: $276.4MQ1 2025: $182.6MQ2 2025: $704Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SLRN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20252$704
Q1 2025106$182.6M
Q4 2024126$276.4M
Q3 2024122$430.2M
Q2 2024113$383.7M
Q1 2024109$613.2M
Q4 2023110$632.6M
Q3 2023102$847.0M
Q2 202382$1.60B
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding ACELYRIN, Inc.; share changes are against Q3 2023.

Institutions holding SLRN in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
AyurMaya Capital Management Company, LP9,334,735$69.6M100.00%00.0%Unchanged
FMR LLC8,822,271$65.8M0.01%−139,455−1.6%Reduced
Citadel Advisors LLC6,474,048$48.3M0.05%+547,355+9.2%Added
Vanguard Group Inc6,155,910$45.9M0.00%+2,966,883+93.0%Added
Opaleye Management Inc.4,146,138$30.9M8.30%00.0%Unchanged
OrbiMed Advisors LLC4,001,711$29.9M0.60%−1,324,591−24.9%Reduced
venBio Partners LLC3,852,470$28.7M4.31%00.0%Unchanged
JPMorgan Chase & Co3,188,477$23.8M0.00%+24,386+0.8%Added
Artal Group S.A.3,035,888$22.6M0.77%+566,609+22.9%Added
BlackRock Inc.2,907,558$21.7M0.00%+709,436+32.3%Added
Tybourne Capital Management (HK) Ltd2,906,629$21.7M3.23%+676,187+30.3%Added
General Atlantic LLC2,889,668$21.6M0.31%00.0%Unchanged
Samsara BioCapital, LLC2,523,022$18.8M2.93%+141,443+5.9%Added
Blue Owl Capital Holdings LP2,292,990$17.1M4.09%+2,292,990New
Ikarian Capital, LLC1,991,005$14.9M4.06%−927,421−31.8%Reduced
Janus Henderson Group PLC1,602,155$12.0M0.01%−192,537−10.7%Reduced
Decheng Capital LLC1,370,951$10.2M2.86%+1,370,951New
Logos Global Management LP1,250,000$9.32M1.04%+1,250,000New
Kynam Capital Management, LP1,200,000$8.95M1.01%00.0%Unchanged
Goldman Sachs Group Inc1,118,911$8.35M0.00%−660,914−37.1%Reduced
RTW Investments, LP978,310$7.30M0.11%00.0%Unchanged
Woodline Partners LP948,559$7.08M0.08%+40,646+4.5%Added
VR Adviser, LLC937,113$6.99M0.48%+72,781+8.4%Added
Marshall Wace, LLP894,182$6.67M0.01%00.0%Unchanged
Morgan Stanley881,719$6.58M0.00%+632,146+253.3%Added
Franklin Resources Inc805,668$6.01M0.00%00.0%Unchanged
Geode Capital Management, LLC774,131$5.78M0.00%+65,351+9.2%Added
State Street Corp664,938$4.96M0.00%−1,315,378−66.4%Reduced
StemPoint Capital LP587,373$4.38M1.18%+587,373New
Walleye Capital LLC577,492$4.31M0.06%+130,137+29.1%Added
Kennedy Capital Management, Inc.474,006$3.54M0.08%+474,006New
Point72 Asset Management, L.P.444,992$3.32M0.01%+286,192+180.2%Added
DAFNA Capital Management LLC371,200$2.77M0.66%+363,900+4,984.9%Added
Eagle Asset Management Inc358,734$2.68M0.01%+371+0.1%Added
Superstring Capital Management LP356,924$2.66M1.90%+356,924New
Sectoral Asset Management Inc325,549$2.43M1.05%+325,549New
Vontobel Holding Ltd.325,549$2.43M0.02%+325,549New
Northern Trust Corp290,455$2.17M0.00%+10,480+3.7%Added
Charles Schwab Investment Management Inc247,756$1.85M0.00%+3,934+1.6%Added
Adage Capital Partners GP, L.L.C.180,000$1.34M0.00%+80,000+80.0%Added
Cubist Systematic Strategies, LLC158,967$1.19M0.01%+158,967New
Point72 Europe (London) LLP122,971$917.4K0.11%+122,971New
Voloridge Investment Management, LLC103,677$773.4K0.00%+103,677New
Boothbay Fund Management, LLC100,346$748.6K0.03%+100,346New
Ameriprise Financial Inc96,691$721.3K0.00%+28,618+42.0%Added
Bank of New York Mellon Corp95,710$714.0K0.00%+3,009+3.2%Added
Lighthouse Investment Partners, LLC86,651$646.4K0.05%+86,651New
Bank of America Corp83,280$621.3K0.00%−141,989−63.0%Reduced
Prudential Financial Inc78,443$585.2K0.00%+78,443New
Ghisallo Capital Management LLC70,000$522.2K0.05%00.0%Unchanged
Nuveen Asset Management, LLC67,771$505.6K0.00%+22,835+50.8%Added
Alps Advisors Inc64,627$482.1K0.00%+64,627New
Squarepoint Ops LLC62,907$469.3K0.00%+62,907New
UBS Oconnor LLC60,000$447.6K0.01%+60,000New
PDT Partners, LLC57,896$431.9K0.05%−36,706−38.8%Reduced
683 Capital Management, LLC53,630$400.1K0.04%+53,630New
Landscape Capital Management, L.L.C.51,016$380.6K0.03%+51,016New
Alyeska Investment Group, L.P.50,070$373.5K0.00%00.0%Unchanged
Jump Financial, LLC49,500$369.3K0.01%+29,908+152.7%Added
Barclays PLC49,484$369.1K0.00%−57,204−53.6%Reduced
Rhumbline Advisers45,247$337.5K0.00%+1,095+2.5%Added
STRS Ohio42,300$315.0K0.00%+35,300+504.3%Added
Swiss National Bank38,300$285.7K0.00%−25,800−40.2%Reduced
Jane Street Group, LLC33,628$250.9K0.00%+33,628New
Legal & General Group Plc30,646$228.6K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)29,281$218.4K0.00%+27,041+1,207.2%Added
Capstone Investment Advisors, LLC27,345$204.0K0.00%+27,345New
Alliancebernstein L.P.24,930$186.0K0.00%00.0%Unchanged
State of Wisconsin Investment Board23,442$174.9K0.00%−14,148−37.6%Reduced
Susquehanna International Group, LLP23,096$172.3K0.00%+9,691+72.3%Added
California State Teachers Retirement System22,746$169.7K0.00%−10,717−32.0%Reduced
Manufacturers Life Insurance Company, The22,368$166.9K0.00%−33,324−59.8%Reduced
EntryPoint Capital, LLC20,968$156.4K0.15%+20,968New
Y-Intercept (Hong Kong) Ltd20,565$153.4K0.01%+20,565New
Invesco Ltd.20,350$151.8K0.00%+2,397+13.4%Added
Ausdal Financial Partners, Inc.20,300$151.4K0.02%−700−3.3%Reduced
Wells Fargo & Company19,915$148.6K0.00%−36,760−64.9%Reduced
Credit Suisse AG19,312$144.1K0.00%−8,177−29.7%Reduced
MetLife Investment Management18,159$135.5K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.17,038$127.1K0.00%−3,158−15.6%Reduced
American International Group, Inc.16,475$122.9K0.00%−66−0.4%Reduced
SG Americas Securities, LLC14,741$110.0K0.00%+14,741New
Deutsche Bank AG14,516$108.3K0.00%−819−5.3%Reduced
Dynamic Technology Lab Private Ltd14,431$108.0K0.01%+14,431New
Voya Investment Management LLC13,430$100.2K0.00%00.0%Unchanged
New York State Common Retirement Fund13,181$98.3K0.00%+6,032+84.4%Added
Virtus ETF Advisers LLC12,717$94.9K0.06%+12,717New
ProShare Advisors LLC11,695$87.2K0.00%+11,695New
China Universal Asset Management Co., Ltd.11,259$84.0K0.02%+11,259New
Bridgefront Capital, LLC11,249$83.9K0.06%+11,249New
Royal Bank of Canada10,664$80.0K0.00%+5,716+115.5%Added
Zurcher Kantonalbank (Zurich Cantonalbank)10,716$79.9K0.00%+9,203+608.3%Added
Raymond James & Associates10,522$78.5K0.00%−8,034−43.3%Reduced
Prelude Capital Management, LLC10,506$78.4K0.01%+10,506New
Group One Trading, L.P.9,814$73.2K0.00%−3,136−24.2%Reduced
Cutler Group LP8,200$61.0K0.01%−2,100−20.4%Reduced
ADAR1 Capital Management, LLC7,000$52.2K0.02%+7,000New
Citigroup Inc6,500$48.5K0.00%−66,769−91.1%Reduced
Sandia Investment Management LP5,980$44.6K0.03%−4,020−40.2%Reduced
Amalgamated Bank3,899$29.0K0.00%−382−8.9%Reduced