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ACELYRIN, Inc.

SLRNDelisted May 21, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001962918

ACELYRIN, Inc. was delisted on May 21, 2025; its insiders filed their last Form 4 on May 23, 2025; 106 institutions reported holding it in 13F filings for Q1 2025, worth $182.6M in total; no superinvestor held it.

13F holders, Q3 2023

Institutional positions in ACELYRIN, Inc. as of Sep 30, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
102
+20 vs. Q2 2023
Shares held
83.8M
+6.63M (+8.6%) vs. Q2 2023
Total value
$847.0M
−$755.8M (−47.2%) vs. Q2 2023
New holders
48
20 more added
Sold out
28
23 more reduced

Compare with Q2 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLRN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2023: 102 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 0 institutionsQ2 2023: 82 institutionsQ3 2023: 102 institutionsQ4 2023: 110 institutionsQ1 2024: 109 institutionsQ2 2024: 113 institutionsQ3 2024: 122 institutionsQ4 2024: 126 institutionsQ1 2025: 106 institutionsQ2 2025: 2 institutionsQ3 2025: 0 institutionsQ4 2025: 0 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ3 2023: $847.0M
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $0Q2 2023: $1.60BQ3 2023: $847.0MQ4 2023: $632.6MQ1 2024: $613.2MQ2 2024: $383.7MQ3 2024: $430.2MQ4 2024: $276.4MQ1 2025: $182.6MQ2 2025: $704Q3 2025: $0Q4 2025: $0Q1 2026: $0Q2 2026: $0
Institutions holding SLRN and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20250$0
Q3 20250$0
Q2 20252$704
Q1 2025106$182.6M
Q4 2024126$276.4M
Q3 2024122$430.2M
Q2 2024113$383.7M
Q1 2024109$613.2M
Q4 2023110$632.6M
Q3 2023102$847.0M
Q2 202382$1.60B
Q1 20230$0
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2023

Shares, value and share of portfolio for each institution holding ACELYRIN, Inc.; share changes are against Q2 2023.

Institutions holding SLRN in Q3 2023
InstitutionSharesValue% of portfolioChange in sharesAction
AyurMaya Capital Management Company, LP9,334,735$94.9M100.00%00.0%Unchanged
FMR LLC8,961,726$89.9M0.01%+1,505,488+20.2%Added
Citadel Advisors LLC5,926,693$57.9M0.06%−112,964−1.9%Reduced
OrbiMed Advisors LLC5,326,302$54.2M1.25%00.0%Unchanged
Opaleye Management Inc.4,146,138$42.2M13.85%−12,500−0.3%Reduced
venBio Partners LLC3,852,470$39.2M11.11%−4,760−0.1%Reduced
Vanguard Group Inc3,189,027$32.4M0.00%+116,847+3.8%Added
JPMorgan Chase & Co3,164,091$32.2M0.00%−539,247−14.6%Reduced
Ikarian Capital, LLC2,918,426$29.7M11.02%00.0%Unchanged
General Atlantic LLC2,889,668$29.4M0.45%+1,389,668+92.6%Added
Artal Group S.A.2,469,279$25.1M1.09%+648,065+35.6%Added
Samsara BioCapital, LLC2,381,579$24.2M7.41%+125,557+5.6%Added
CHI Advisors LLC2,262,990$23.0M9.13%−400,816−15.0%Reduced
Tybourne Capital Management (HK) Ltd2,230,442$22.7M3.17%00.0%Unchanged
BlackRock Inc.2,198,122$22.4M0.00%+1,350,227+159.2%Added
State Street Corp1,980,316$20.1M0.00%+1,863,316+1,592.6%Added
Goldman Sachs Group Inc1,779,825$18.1M0.00%+1,469,827+474.1%Added
Janus Henderson Group PLC1,794,692$16.4M0.01%+1,794,692New
Decheng Capital Management III (Cayman), LLC1,548,317$15.7M5.26%−6,100−0.4%Reduced
EcoR1 Capital, LLC1,402,201$14.3M0.49%+1,402,201New
Driehaus Capital Management LLC1,319,349$13.4M0.17%−439,448−25.0%Reduced
Kynam Capital Management, LP1,200,000$12.2M2.03%+1,200,000New
RTW Investments, LP978,310$9.95M0.21%00.0%Unchanged
Woodline Partners LP907,913$9.23M0.11%−127,642−12.3%Reduced
Marshall Wace, LLP894,182$9.09M0.02%−267,346−23.0%Reduced
VR Adviser, LLC864,332$8.79M0.93%+864,332New
Franklin Resources Inc805,668$8.19M0.00%−73,600−8.4%Reduced
Geode Capital Management, LLC708,780$7.21M0.00%+361,012+103.8%Added
Massachusetts Financial Services Co642,158$6.53M0.00%+1,090+0.2%Added
Deep Track Capital, LP551,289$5.61M0.22%+551,289New
Price T Rowe Associates Inc458,261$4.66M0.00%−431,121−48.5%Reduced
Walleye Capital LLC447,355$4.55M0.07%+447,355New
Eagle Asset Management Inc358,363$3.64M0.02%−161,687−31.1%Reduced
Northern Trust Corp279,975$2.85M0.00%+221,850+381.7%Added
Morgan Stanley249,573$2.54M0.00%+231,519+1,282.4%Added
Charles Schwab Investment Management Inc243,822$2.48M0.00%+84,574+53.1%Added
Bank of America Corp225,269$2.29M0.00%+223,428+12,136.2%Added
Schonfeld Strategic Advisors LLC202,662$2.06M0.02%+147,454+267.1%Added
Perceptive Advisors LLC200,000$2.03M0.07%00.0%Unchanged
Ghost Tree Capital, LLC200,000$2.03M0.98%+200,000New
Rafferty Asset Management, LLC173,696$1.77M0.01%+173,696New
Point72 Asset Management, L.P.158,800$1.61M0.01%+158,800New
Tri Locum Partners LP155,573$1.58M0.51%+155,573New
Rock Springs Capital Management LP141,876$1.44M0.04%00.0%Unchanged
Barclays PLC106,688$1.09M0.00%+106,688New
Adage Capital Partners GP, L.L.C.100,000$1.02M0.00%−270,000−73.0%Reduced
Ensign Peak Advisors, Inc100,000$1.02M0.00%00.0%Unchanged
PDT Partners, LLC94,602$962.1K0.12%+94,602New
Bank of New York Mellon Corp92,701$942.8K0.00%+79,478+601.1%Added
TD Asset Management Inc75,164$764.4K0.00%+13,554+22.0%Added
Citigroup Inc73,269$745.1K0.00%+73,269New
Ghisallo Capital Management LLC70,000$711.9K0.07%00.0%Unchanged
Ameriprise Financial Inc68,073$692.3K0.00%−336,750−83.2%Reduced
Swiss National Bank64,100$651.9K0.00%+64,100New
Wells Fargo & Company56,675$576.4K0.00%+56,451+25,201.3%Added
Manufacturers Life Insurance Company, The55,692$566.4K0.00%+13,692+32.6%Added
Fred Alger Management, LLC53,206$541.1K0.00%−956,843−94.7%Reduced
Caption Management, LLC50,377$512.3K0.07%+50,377New
Alyeska Investment Group, L.P.50,070$509.2K0.00%00.0%Unchanged
Nuveen Asset Management, LLC44,936$457.0K0.00%+44,936New
Rhumbline Advisers44,152$449.0K0.00%+44,152New
State of Wisconsin Investment Board37,590$382.3K0.00%+37,590New
California State Teachers Retirement System33,463$340.3K0.00%+33,463New
Walleye Trading LLC31,428$319.6K0.01%+31,428New
Legal & General Group Plc30,646$311.7K0.00%+30,646New
Profund Advisors LLC29,232$297.3K0.02%+29,232New
Credit Suisse AG27,489$279.6K0.00%+27,489New
Alliancebernstein L.P.24,930$253.5K0.00%−1,118,344−97.8%Reduced
Ausdal Financial Partners, Inc.21,000$213.6K0.03%+21,000New
Mirae Asset Global Investments Co., Ltd.20,196$205.4K0.00%+20,196New
Jump Financial, LLC19,592$199.3K0.01%−4,092−17.3%Reduced
Man Group plc–$192.9K0.00%–New
Raymond James & Associates18,556$188.7K0.00%+18,556New
MetLife Investment Management18,159$184.7K0.00%+18,159New
Invesco Ltd.17,953$182.6K0.00%+17,953New
American International Group, Inc.16,541$168.2K0.00%+16,541New
Deutsche Bank AG15,335$156.0K0.00%+15,335New
Voya Investment Management LLC13,430$136.6K0.00%+13,430New
Susquehanna International Group, LLP13,405$136.3K0.00%−36,245−73.0%Reduced
Group One Trading, L.P.12,950$131.7K0.01%+12,950New
XTX Topco Ltd12,401$126.1K0.02%+12,401New
Cutler Group LP10,300$104.0K0.02%+10,300New
Sandia Investment Management LP10,000$101.7K0.03%00.0%Unchanged
DAFNA Capital Management LLC7,300$74.2K0.02%+7,300New
New York State Common Retirement Fund7,149$72.7K0.00%+7,149New
STRS Ohio7,000$71.0K0.00%+7,000New
Royal Bank of Canada4,948$50.0K0.00%−26,046−84.0%Reduced
Amalgamated Bank4,281$44.0K0.00%+4,281New
Ameritas Investment Partners, Inc.3,322$33.8K0.00%+3,322New
Tower Research Capital LLC (TRC)2,240$22.8K0.00%−845−27.4%Reduced
Metropolitan Life Insurance Co2,004$20.4K0.00%+2,004New
Zurcher Kantonalbank (Zurich Cantonalbank)1,513$15.4K0.00%+1,513New
Advisor Group Holdings, Inc.1,449$14.7K0.00%+255+21.4%Added
UBS Group AG518$5.27K0.00%−1,563−75.1%Reduced
Lindbrook Capital, LLC316$3.21K0.00%+316New
Creative Financial Designs Inc300$3.05K0.00%+300New
Meeder Asset Management Inc122$1.24K0.00%+122New
Private Trust Co NA108$1.10K0.00%−41−27.5%Reduced
US Bancorp32$3250.00%−154−82.8%Reduced
Institutional & Family Asset Management, LLC21$2140.00%+21New