Prime Medicine, Inc.

PRME

Exchange: Nasdaq
Industry: Biological Products, (No Diagnostic Substances)
SEC CIK: 0001894562

SEC filings (opens in a new tab)

No open-market purchases or sales by Prime Medicine, Inc. insiders were filed in the last 90 days; 187 institutions reported holding it in 13F filings for Q2 2026, worth $393.5M in total; ARK Invest is the only superinvestor holding it.

Q4 2024 vs. Q3 2024

How the institutions holding Prime Medicine, Inc. changed between Q3 2024 and Q4 2024.

All holders in Q4 2024 All holders in Q3 2024

13F holders of PRME: Q3 2024 compared with Q4 2024
Measure	Q3 2024	Of which not filed for Q4 2024	Q4 2024	Change
Holders	116	2	132	+18
Shares	68.7M	46.3K	64.3M	−4.33M (−6.3%)
Value	$265.9M	$179.0K	$188.0M	−$77.7M (−29.2%)

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so the changes leave them out.

New holders (35)

Institutions that held Prime Medicine, Inc. at the end of Q4 2024 but not at the end of Q3 2024.

Institutions new to PRME in Q4 2024
Institution	Shares	Value	% of portfolio
Susquehanna Fundamental Investments, LLC	144,719	$422.6K	0.01%
ExodusPoint Capital Management, LP	131,732	$385.0K	0.00%
Aristides Capital LLC	70,500	$205.9K	0.06%
Point72 Asset Management, L.P.	68,528	$200.1K	0.00%
Green Alpha Advisors, LLC	64,406	$188.1K	0.15%
Sculptor Capital LP	50,700	$148.0K	0.00%
Crestwood Advisors Group LLC	31,687	$92.5K	0.00%
PEAK6 LLC	30,013	$87.6K	0.00%
Creative Planning	27,623	$80.7K	0.00%
Prime Capital Investment Advisors, LLC	23,955	$69.9K	0.00%
Avanza Fonder AB	22,480	$65.6K	0.00%
HRT Financial LP	21,695	$63.0K	0.00%
Sherbrooke Park Advisers LLC	20,441	$59.7K	0.02%
BNP Paribas Arbitrage, SA	20,096	$58.7K	0.00%
Impact Partnership Wealth, LLC	17,274	$50.4K	0.01%
Police & Firemen's Retirement System of New Jersey	17,092	$49.9K	0.00%
Balyasny Asset Management LLC	16,342	$47.7K	0.00%
AQR Capital Management LLC	16,046	$46.9K	0.00%
Axq Capital, LP	15,363	$44.9K	0.02%
XTX Topco Ltd	14,466	$42.2K	0.00%
JustInvest LLC	12,378	$36.1K	0.00%
American Century Companies Inc	11,426	$33.4K	0.00%
GF Fund Management Co. Ltd.	2,700	$7.88K	0.00%
R Squared Ltd	2,230	$6.51K	0.01%
Skopos Labs, Inc.	1,894	$5.53K	0.00%
Simplex Trading, LLC	1,458	$4.00K	0.00%
SBI Securities Co., Ltd.	1,205	$3.52K	0.00%
Point72 (DIFC) Ltd	309	$902	0.00%
Rothschild Investment LLC	280	$818	0.00%
Raffa Wealth Management, LLC	250	$730	0.00%
US Bancorp	202	$590	0.00%
Allworth Financial LP	141	$449	0.00%
Massmutual Trust Co FSB	104	$304	0.00%
Catherine Avery Investment Management LLC	67	$196	0.00%
IFP Advisors, Inc	24	$70	0.00%

Sold out (17)

Institutions that held Prime Medicine, Inc. at the end of Q3 2024 and filed for Q4 2024 without it.

Institutions that sold out of PRME in Q4 2024
Institution	Shares, Q3 2024	Value, Q3 2024
Vestal Point Capital, LP	1,070,000	$4.14M
Deerfield Management Company, L.P. (Series C)	896,960	$3.47M
Avidity Partners Management LP	694,000	$2.69M
Trexquant Investment LP	242,160	$937.2K
D. E. Shaw & Co., Inc.	139,451	$539.7K
Squarepoint Ops LLC	124,369	$481.3K
Sphera Funds Management Ltd.	76,456	$295.9K
Citadel Advisors LLC	50,995	$197.4K
Ameriprise Financial Inc	28,801	$111.5K
Voloridge Investment Management, LLC	27,119	$105.0K
Renaissance Technologies LLC	20,000	$77.4K
Corsair Capital Management, L.P.	20,000	$77.4K
Paloma Partners Management Co	11,587	$44.8K
Acadian Asset Management LLC	10,886	$42.0K
Brown Brothers Harriman & Co	10,065	$39.0K
GAMMA Investing LLC	654	$2.53K
SRS Capital Advisors, Inc.	139	$538

Not filed for Q4 2024 yet (2)

Institutions that held Prime Medicine, Inc. at the end of Q3 2024 and haven't filed a 13F for Q4 2024. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding PRME in Q3 2024 that haven't filed for Q4 2024
Institution	Shares, Q3 2024	Value, Q3 2024
PEAK6 Investments LLC	45,013	$174.2K
Abich Financial Wealth Management LLC	1,247	$4.83K