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Palisade Bio, Inc.

PALI
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001357459

In the last 90 days, Palisade Bio, Inc. insiders filed 3 open-market purchases and 2 sales; 124 institutions reported holding it in 13F filings for Q2 2026, worth $362.4M in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Palisade Bio, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
86
+74 vs. Q3 2025
Shares held
135.9M
+135.8M (+113,515.5%) vs. Q3 2025
Total value
$319.4M
+$319.3M (+310,511.8%) vs. Q3 2025
New holders
75
7 more added
Sold out
1
1 more reduced

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PALI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 86 institutions
Q1 2021: 0 institutionsQ2 2021: 23 institutionsQ3 2021: 22 institutionsQ4 2021: 28 institutionsQ1 2022: 25 institutionsQ2 2022: 26 institutionsQ3 2022: 33 institutionsQ4 2022: 12 institutionsQ1 2023: 9 institutionsQ2 2023: 11 institutionsQ3 2023: 13 institutionsQ4 2023: 16 institutionsQ1 2024: 16 institutionsQ2 2024: 8 institutionsQ3 2024: 9 institutionsQ4 2024: 10 institutionsQ1 2025: 13 institutionsQ2 2025: 11 institutionsQ3 2025: 12 institutionsQ4 2025: 86 institutionsQ1 2026: 96 institutionsQ2 2026: 124 institutions
Value heldQ4 2025: $319.4M
Q1 2021: $0Q2 2021: $10.1MQ3 2021: $2.03MQ4 2021: $1.70MQ1 2022: $930.0KQ2 2022: $395.0KQ3 2022: $842.0KQ4 2022: $648.0KQ1 2023: $29.8KQ2 2023: $228.7KQ3 2023: $86.6KQ4 2023: $158.3KQ1 2024: $384.6KQ2 2024: $297.7KQ3 2024: $347.4KQ4 2024: $387.7KQ1 2025: $200.9KQ2 2025: $57.5KQ3 2025: $102.8KQ4 2025: $319.4MQ1 2026: $261.7MQ2 2026: $362.4M
Institutions holding PALI and their total value by quarter
QuarterHoldersValue
Q2 2026124$362.4M
Q1 202696$261.7M
Q4 202586$319.4M
Q3 202512$102.8K
Q2 202511$57.5K
Q1 202513$200.9K
Q4 202410$387.7K
Q3 20249$347.4K
Q2 20248$297.7K
Q1 202416$384.6K
Q4 202316$158.3K
Q3 202313$86.6K
Q2 202311$228.7K
Q1 20239$29.8K
Q4 202212$648.0K
Q3 202233$842.0K
Q2 202226$395.0K
Q1 202225$930.0K
Q4 202128$1.70M
Q3 202122$2.03M
Q2 202123$10.1M
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Palisade Bio, Inc.; share changes are against Q3 2025.

Institutions holding PALI in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Perceptive Advisors LLC12,050,000$28.3M0.52%+12,050,000New
Commodore Capital LP11,445,000$26.9M1.79%+11,445,000New
Janus Henderson Group PLC10,540,334$24.8M0.01%+10,540,334New
Point72 Asset Management, L.P.10,495,252$24.7M0.04%+10,495,252New
Octagon Capital Advisors LP9,567,898$22.5M2.81%+9,567,898New
Ra Capital Management, L.P.7,124,116$16.7M0.17%+7,124,116New
Ameriprise Financial Inc6,911,237$16.2M0.00%+6,911,237New
Eversept Partners, LP5,391,548$12.7M0.71%+5,391,548New
Franklin Resources Inc5,092,562$12.0M0.00%+5,092,562New
Boxer Capital Management, LLC4,799,875$11.3M2.47%+4,799,875New
Adage Capital Partners GP, L.L.C.4,500,000$10.6M0.02%+4,500,000New
B Group, Inc.4,500,000$10.6M7.84%+4,500,000New
Squadron Capital Management LLC4,500,000$10.6M4.72%+4,500,000New
StemPoint Capital LP4,192,375$9.85M1.69%+4,192,375New
Morgan Stanley4,142,446$9.73M0.00%+4,133,828+47,967.4%Added
Renaissance Technologies LLC2,382,500$5.60M0.01%+2,382,500New
Vivo Capital, LLC2,293,578$5.39M0.35%+2,293,578New
Vanguard Group Inc2,115,622$4.97M0.00%+2,115,622New
ADAR1 Capital Management, LLC2,004,845$4.71M0.35%+2,004,845New
Artia Global Partners LP1,992,367$4.68M0.75%+1,992,367New
BlackRock, Inc.1,879,319$4.42M0.00%+1,879,319New
OrbiMed Advisors LLC1,871,420$4.40M0.09%+1,871,420New
Citadel Advisors LLC1,701,411$4.00M0.00%+1,701,411New
Price T Rowe Associates Inc1,577,856$3.71M0.00%+1,577,856New
Geode Capital Management, LLC1,565,452$3.68M0.00%+1,538,832+5,780.7%Added
HighVista Strategies LLC1,300,031$3.06M0.79%+1,300,031New
Exome Asset Management LLC758,203$1.78M0.88%+758,203New
Platinum Investment Management Ltd664,087$1.56M0.36%+664,087New
Hudson Bay Capital Management LP656,460$1.54M0.01%+656,460New
State Street Corp643,997$1.51M0.00%+643,997New
Goldman Sachs Group Inc557,565$1.31M0.00%+557,565New
Persistent Asset Partners Ltd416,035$977.7K0.47%+416,035New
Resolute Capital Asset Partners LLC400,000$940.0K0.45%+400,000New
Superstring Capital Management LP367,103$862.7K0.46%+367,103New
Jane Street Group, LLC343,686$807.7K0.00%+343,686New
Seven Fleet Capital Management LP327,500$769.6K0.52%+327,500New
Balyasny Asset Management LLC325,367$764.6K0.00%+325,367New
Squarepoint Ops LLC322,090$756.9K0.00%+322,090New
Creek Drive Management Group LLC307,500$722.6K0.53%+307,500New
BIT Capital GmbH305,000$716.8K0.03%+305,000New
Millennium Management LLC294,486$692.0K0.00%+294,486New
Northern Trust Corp283,147$665.4K0.00%+283,147New
Ikarian Capital, LLC274,978$646.2K0.08%+274,978New
UBS Group AG247,754$582.2K0.00%+228,341+1,176.2%Added
Quadrature Capital Ltd240,586$565.4K0.01%+240,586New
Susquehanna International Group, LLP212,659$499.7K0.00%+212,659New
Scientech Research LLC211,441$496.9K0.31%+211,441New
TD Asset Management Inc204,448$480.5K0.00%+204,448New
Sphera Funds Management Ltd.184,100$432.6K0.09%+184,100New
Diadema Partners LP166,049$390.2K0.23%+166,049New
ACT Capital Management, LLC150,000$352.5K0.29%+150,000New
Boothbay Fund Management, LLC132,648$311.7K0.01%+132,648New
Omers Administration Corp108,000$253.8K0.00%+108,000New
Manufacturers Life Insurance Company, The106,636$251.7K0.00%+106,636New
Silverarc Capital Management, LLC102,108$240.0K0.03%+102,108New
Pale Fire Capital SE70,710$166.2K0.02%+70,710New
Bank of America Corp70,097$164.7K0.00%+70,011+81,408.1%Added
Citigroup Inc52,281$122.9K0.00%+49,934+2,127.6%Added
Jefferies Financial Group Inc.46,761$109.9K0.00%+46,761New
Virtus ETF Advisers LLC46,000$108.1K0.05%+46,000New
Lighthouse Investment Partners, LLC39,480$92.8K0.00%+39,480New
Caitong International Asset Management Co., Ltd34,504$81.1K0.02%+34,504New
Total Clarity Wealth Management, Inc.29,935$70.3K0.02%+29,935New
Two Sigma Investments, LP27,640$65.0K0.00%+27,640New
XTX Topco Ltd21,669$50.9K0.00%+7,584+53.8%Added
Vontobel Holding Ltd.20,000$47.0K0.00%+20,000New
Commonwealth Equity Services, LLC16,650$39.1K0.00%+16,650New
Victory Capital Management Inc16,072$37.8K0.00%+16,072New
LPL Financial LLC15,154$35.6K0.00%+15,154New
Newbridge Financial Services Group, Inc.15,000$35.3K0.01%+2,000+15.4%Added
Winton Group Ltd14,891$35.0K0.00%+14,891New
Barclays PLC14,780$34.7K0.00%+14,780New
Atom Investors LP14,041$33.0K0.00%+14,041New
Bank of New York Mellon Corp12,912$30.3K0.00%+12,912New
Virtu Financial LLC11,870$28.0K0.00%+11,870New
Schonfeld Strategic Advisors LLC11,231$26.4K0.00%+11,231New
Cetera Investment Advisers10,512$24.7K0.00%+10,512New
FNY Investment Advisers, LLC9,951$23.0K0.01%+9,951New
Tower Research Capital LLC (TRC)1,025$2.41K0.00%−4,371−81.0%Reduced
Rockefeller Capital Management L.P.500$1.18K0.00%00.0%Unchanged
Avion Wealth500$1.00K0.00%+500New
Federation des caisses Desjardins du Quebec100$2350.00%00.0%Unchanged
Advisor Group Holdings, Inc.66$1550.00%+66New
SHP Wealth Management50$1180.00%+50New
Wells Fargo & Company21$490.00%00.0%Unchanged
FMR LLC10$240.00%+10New
Two Sigma Securities, LLC0$00.00%−29,406−100.0%Sold out