Pacific Biosciences of California, Inc.
PACB- Exchange
- Nasdaq
- Industry
- Laboratory Analytical Instruments
- SEC CIK
- 0001299130
In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.
13F holders, Q4 2025
Institutional positions in Pacific Biosciences of California, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 216
- +12 vs. Q3 2025
- Shares held
- 200.7M
- +18.9M (+10.4%) vs. Q3 2025
- Total value
- $373.5M
- +$141.3M (+60.8%) vs. Q3 2025
- New holders
- 43
- 69 more added
- Sold out
- 31
- 50 more reduced
4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 223 | $320.8M |
| Q1 2026 | 231 | $248.5M |
| Q4 2025 | 216 | $373.5M |
| Q3 2025 | 208 | $237.8M |
| Q2 2025 | 207 | $245.8M |
| Q1 2025 | 225 | $265.6M |
| Q4 2024 | 227 | $475.1M |
| Q3 2024 | 226 | $394.3M |
| Q2 2024 | 229 | $331.9M |
| Q1 2024 | 268 | $1.01B |
| Q4 2023 | 274 | $2.76B |
| Q3 2023 | 275 | $2.20B |
| Q2 2023 | 272 | $3.37B |
| Q1 2023 | 260 | $2.93B |
| Q4 2022 | 237 | $1.84B |
| Q3 2022 | 227 | $1.23B |
| Q2 2022 | 230 | $1.03B |
| Q1 2022 | 250 | $2.03B |
| Q4 2021 | 256 | $4.20B |
| Q3 2021 | 246 | $4.83B |
| Q2 2021 | 261 | $6.04B |
| Q1 2021 | 263 | $5.47B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| ARK Investment Management LLCSuperinvestorARK Invest | 37,264,228 | $69.7M | 0.46% | +6,340,125+20.5% | Added |
| BlackRock, Inc. | 23,344,970 | $43.7M | 0.00% | +649,218+2.9% | Added |
| Softbank Group Corp | 20,451,570 | $38.2M | 0.25% | 00.0% | Unchanged |
| Vanguard Group Inc | 17,037,314 | $31.9M | 0.00% | +657,342+4.0% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 7,808,580 | $14.6M | 0.01% | −868,978−10.0% | Reduced |
| Nikko Asset Management Americas, Inc. | 7,808,580 | $14.6M | 0.17% | −868,978−10.0% | Reduced |
| Geode Capital Management, LLC | 7,078,744 | $13.2M | 0.00% | +172,089+2.5% | Added |
| State Street Corp | 5,912,223 | $11.1M | 0.00% | +2,5790.0% | Added |
| D. E. Shaw & Co., Inc. | 4,438,273 | $8.30M | 0.01% | +4,438,273 | New |
| Millennium Management LLC | 4,344,569 | $8.12M | 0.01% | −572,226−11.6% | Reduced |
| Casdin Capital, LLC | 4,223,767 | $7.90M | 0.49% | +3,500,000+483.6% | Added |
| Renaissance Technologies LLC | 3,850,600 | $7.20M | 0.01% | +3,850,600 | New |
| UBS Group AG | 3,171,546 | $5.93M | 0.00% | +1,674,320+111.8% | Added |
| Citadel Advisors LLC | 3,166,241 | $5.92M | 0.00% | +667,887+26.7% | Added |
| Point72 Asset Management, L.P. | 2,957,400 | $5.53M | 0.01% | +2,957,400 | New |
| Two Sigma Investments, LP | 2,877,184 | $5.38M | 0.01% | +2,475,418+616.1% | Added |
| Susquehanna International Group, LLP | 2,611,543 | $4.88M | 0.01% | +1,236,284+89.9% | Added |
| Koss-Olinger Consulting, LLC | 2,600,000 | $4.86M | 0.38% | −700,000−21.2% | Reduced |
| Charles Schwab Investment Management Inc | 2,465,853 | $4.61M | 0.00% | +38,499+1.6% | Added |
| Morgan Stanley | 2,410,540 | $4.51M | 0.00% | +1,959,325+434.2% | Added |
| Northern Trust Corp | 2,046,839 | $3.83M | 0.00% | −242,057−10.6% | Reduced |
| Davy Global Fund Management Ltd | 1,894,931 | $3.54M | 0.24% | +606,239+47.0% | Added |
| Bank of America Corp | 1,854,814 | $3.47M | 0.00% | +382,124+25.9% | Added |
| Amiral Gestion | 2,733,290 | $3.21M | 1.18% | 00.0% | Unchanged |
| Jane Street Group, LLC | 1,500,518 | $2.81M | 0.00% | +1,263,495+533.1% | Added |
| Invesco Ltd. | 1,433,011 | $2.68M | 0.00% | +326,238+29.5% | Added |
| Goldman Sachs Group Inc | 1,378,872 | $2.58M | 0.00% | +869,445+170.7% | Added |
| HRT Financial LP | 1,363,577 | $2.55M | 0.01% | +1,363,577 | New |
| Bourne Lent Asset Management Inc | 967,055 | $1.81M | 0.60% | 00.0% | Unchanged |
| HHLR Advisors, Ltd.SuperinvestorHHLR Advisors (Hillhouse) | 918,892 | $1.72M | 0.06% | 00.0% | Unchanged |
| Nuveen, LLC | 848,219 | $1.59M | 0.00% | +578,035+213.9% | Added |
| Bank of New York Mellon Corp | 834,573 | $1.56M | 0.00% | +29,017+3.6% | Added |
| Two Sigma Advisers, LP | 827,500 | $1.55M | 0.00% | +827,500 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 808,700 | $1.40M | 0.00% | 00.0% | Unchanged |
| Headlands Technologies LLC | 733,840 | $1.37M | 0.11% | +733,840 | New |
| Caxton Associates LLP | 641,724 | $1.20M | 0.02% | +641,724 | New |
| XTX Topco Ltd | 628,222 | $1.17M | 0.03% | +615,907+5,001.3% | Added |
| Mirador Capital Partners LP | 591,005 | $1.11M | 0.15% | +9,612+1.7% | Added |
| Vestmark Advisory Solutions, Inc. | 550,344 | $1.03M | 0.01% | −51,179−8.5% | Reduced |
| Creative Planning | 519,726 | $971.9K | 0.00% | +200,876+63.0% | Added |
| Birchview Capital, LP | 500,000 | $935.0K | 0.55% | 00.0% | Unchanged |
| Barclays PLC | 472,108 | $882.8K | 0.00% | +72,201+18.1% | Added |
| Carret Asset Management, LLC | 470,000 | $878.9K | 0.08% | +50,000+11.9% | Added |
| ArrowMark Colorado Holdings LLC | 468,382 | $875.9K | 0.02% | 00.0% | Unchanged |
| Group One Trading, L.P. | 460,250 | $860.7K | 0.03% | +5,382+1.2% | Added |
| JPMorgan Chase & Co | 456,908 | $854.4K | 0.00% | −11,972−2.6% | Reduced |
| Squarepoint Ops LLC | 448,558 | $838.8K | 0.00% | −483,518−51.9% | Reduced |
| Acadian Asset Management LLC | 441,250 | $822.0K | 0.00% | +418,134+1,808.9% | Added |
| Alliancebernstein L.P. | 387,060 | $723.8K | 0.00% | 00.0% | Unchanged |
| Rhumbline Advisers | 360,963 | $675.0K | 0.00% | −54,716−13.2% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 325,139 | $608.0K | 0.00% | −110.0% | Reduced |
| Dimensional Fund Advisors LP | 323,749 | $603.5K | 0.00% | −39,074−10.8% | Reduced |
| Wells Fargo & Company | 314,014 | $587.2K | 0.00% | +82,059+35.4% | Added |
| Gsa Capital Partners LLP | 305,177 | $571.0K | 0.05% | −104,193−25.5% | Reduced |
| LPL Financial LLC | 274,247 | $512.8K | 0.00% | +60,124+28.1% | Added |
| Scientech Research LLC | 252,887 | $472.9K | 0.30% | +252,887 | New |
| Deutsche Bank AG | 218,981 | $409.5K | 0.00% | +10,107+4.8% | Added |
| Quadrature Capital Ltd | 206,410 | $386.0K | 0.00% | −145,945−41.4% | Reduced |
| Graham Capital Management, L.P. | 188,485 | $352.5K | 0.01% | +188,485 | New |
| Green Alpha Advisors, LLC | 183,466 | $343.1K | 0.31% | +9,441+5.4% | Added |
| Raymond James Financial Inc | 183,278 | $342.7K | 0.00% | +21,413+13.2% | Added |
| Price T Rowe Associates Inc | 163,527 | $306.0K | 0.00% | +17,663+12.1% | Added |
| DekaBank Deutsche Girozentrale | 73,300 | $296.0K | 0.00% | 00.0% | Unchanged |
| Polen Capital Management LLC | 137,149 | $256.5K | 0.00% | +137,149 | New |
| Farallon Capital Management, L.L.C. | 135,000 | $252.4K | 0.00% | 00.0% | Unchanged |
| AdvisorNet Financial, Inc | 133,767 | $250.1K | 0.01% | +7,950+6.3% | Added |
| Bank of Montreal | 126,923 | $237.3K | 0.00% | +18,353+16.9% | Added |
| Intech Investment Management LLC | 123,936 | $231.8K | 0.00% | −8,432−6.4% | Reduced |
| Benjamin Edwards Inc | 121,926 | $227.9K | 0.00% | −11,951−8.9% | Reduced |
| Koa Wealth Management, LLC | 120,000 | $224.4K | 0.15% | 00.0% | Unchanged |
| MetLife Investment Management | 116,188 | $217.3K | 0.00% | −20,728−15.1% | Reduced |
| Abacus Wealth Partners, LLC | 113,889 | $213.0K | 0.02% | +113,889 | New |
| Envestnet Asset Management Inc | 104,621 | $195.6K | 0.00% | −36,347−25.8% | Reduced |
| SG Americas Securities, LLC | 100,751 | $188.0K | 0.00% | +30,078+42.6% | Added |
| Gabelli Funds LLC | 100,000 | $187.0K | 0.00% | 00.0% | Unchanged |
| Abacus Planning Group, Inc. | 100,000 | $187.0K | 0.02% | 00.0% | Unchanged |
| American Century Companies Inc | 94,063 | $175.9K | 0.00% | +94,063 | New |
| AQR Capital Management LLC | 86,964 | $162.6K | 0.00% | +35,629+69.4% | Added |
| New York State Common Retirement Fund | 84,825 | $158.6K | 0.00% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 82,527 | $154.3K | 0.00% | −11,315−12.1% | Reduced |
| Steel Peak Wealth Management LLC | 81,422 | $152.3K | 0.01% | +51,492+172.0% | Added |
| Police & Firemen's Retirement System of New Jersey | 79,955 | $149.5K | 0.00% | −1,193−1.5% | Reduced |
| State Board of Administration of Florida Retirement System | 71,941 | $134.5K | 0.00% | 00.0% | Unchanged |
| Stifel Financial Corp | 70,860 | $132.5K | 0.00% | +16,151+29.5% | Added |
| BNP Paribas Arbitrage, SA | 66,055 | $123.5K | 0.00% | +7,729+13.3% | Added |
| ProShare Advisors LLC | 63,799 | $119.3K | 0.00% | +5,883+10.2% | Added |
| TCG Advisory Services, LLC | 61,900 | $115.8K | 0.00% | 00.0% | Unchanged |
| Clear Harbor Asset Management, LLC | 58,710 | $109.8K | 0.01% | −66,584−53.1% | Reduced |
| IFP Advisors, Inc | 52,787 | $98.7K | 0.00% | −42,825−44.8% | Reduced |
| HSBC Holdings PLC | 52,708 | $97.8K | 0.00% | +52,708 | New |
| Voya Investment Management LLC | 51,548 | $96.4K | 0.00% | 00.0% | Unchanged |
| Kestra Private Wealth Services, LLC | 51,200 | $95.7K | 0.00% | +1,300+2.6% | Added |
| Evolution Wealth Advisors, LLC | 50,000 | $93.5K | 0.01% | 00.0% | Unchanged |
| China Universal Asset Management Co., Ltd. | 49,196 | $92.0K | 0.01% | −3,454−6.6% | Reduced |
| Cetera Investment Advisers | 48,943 | $91.5K | 0.00% | −101,238−67.4% | Reduced |
| Wealth Architects, LLC | 48,725 | $91.1K | 0.01% | 00.0% | Unchanged |
| Captrust Financial Advisors | 42,959 | $80.3K | 0.00% | +42,959 | New |
| Mariner, LLC | 40,004 | $74.8K | 0.00% | +28,608+251.0% | Added |
| Wealthfront Advisers LLC | 38,041 | $71.1K | 0.00% | −52,164−57.8% | Reduced |
| Polymer Capital Management (US) LLC | 37,558 | $70.2K | 0.01% | +37,558 | New |