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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q4 2025

Institutional positions in Pacific Biosciences of California, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
216
+12 vs. Q3 2025
Shares held
200.7M
+18.9M (+10.4%) vs. Q3 2025
Total value
$373.5M
+$141.3M (+60.8%) vs. Q3 2025
New holders
43
69 more added
Sold out
31
50 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 216 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ4 2025: $373.5M
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q3 2025.

Institutions holding PACB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Western Wealth Management, LLC35,345$66.1K0.00%−5,000−12.4%Reduced
Sanctuary Advisors, LLC34,880$65.2K0.00%+3,371+10.7%Added
Kestra Advisory Services, LLC34,858$65.2K0.00%+652+1.9%Added
JustInvest LLC33,880$63.4K0.00%−675−2.0%Reduced
Jump Financial, LLC33,746$63.1K0.00%+33,746New
Magnetar Financial LLC31,602$59.1K0.00%+31,602New
Victory Capital Management Inc31,184$58.3K0.00%+725+2.4%Added
Hartline Investment Corp31,000$58.0K0.01%00.0%Unchanged
Venture Visionary Partners LLC30,300$56.7K0.00%00.0%Unchanged
Citigroup Inc30,200$56.5K0.00%+10,620+54.2%Added
Ambassador Advisors, LLC30,000$56.1K0.01%00.0%Unchanged
FMR LLC29,855$55.8K0.00%+11,279+60.7%Added
Axxcess Wealth Management, LLC28,603$53.5K0.00%−257−0.9%Reduced
Sandbox Financial Partners, LLC27,517$51.5K0.01%00.0%Unchanged
Atria Investments LLC27,496$51.4K0.00%+5,735+26.4%Added
Ameritas Investment Partners, Inc.26,094$48.8K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.25,075$46.9K0.00%+4,877+24.1%Added
Private Wealth Partners, LLC25,000$46.8K0.00%+25,000New
Royal Bank of Canada24,891$46.0K0.00%+1,633+7.0%Added
Legal & General Group Plc24,447$45.8K0.00%00.0%Unchanged
Private Advisor Group, LLC24,296$45.4K0.00%−4,323−15.1%Reduced
Russell Investments Group, Ltd.23,900$44.7K0.00%+1,029+4.5%Added
Gallagher Fiduciary Advisors, LLC23,486$43.9K0.00%+1,813+8.4%Added
Cresset Asset Management, LLC22,955$42.9K0.00%00.0%Unchanged
Prudential Financial Inc22,737$42.5K0.00%−12,947−36.3%Reduced
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors22,000$41.1K0.00%+22,000New
Prime Capital Investment Advisors, LLC21,973$41.1K0.00%+166+0.8%Added
Wealth Enhancement Advisory Services, LLC19,337$40.2K0.00%+1,620+9.1%Added
Engineers Gate Manager LP21,471$40.2K0.00%+21,471New
Xponance, Inc.21,467$40.1K0.00%00.0%Unchanged
Neuberger Berman Group LLC21,435$40.1K0.00%+21,435New
Ballentine Partners, LLC20,823$38.9K0.00%+4,342+26.3%Added
Mercer Global Advisors Inc20,663$38.6K0.00%+6,695+47.9%Added
SVB Capital Management, LLC20,586$38.5K1.38%00.0%Unchanged
Great West Life Assurance Co20,280$38.0K0.00%+582+3.0%Added
CIBC World Markets Corp18,268$34.2K0.00%+18,268New
Outlook Wealth Advisors, LLC18,000$33.7K0.01%+18,000New
Pinnacle Wealth Planning Services, Inc.17,849$33.4K0.00%+17,849New
California State Teachers Retirement System16,998$31.8K0.00%−2,836−14.3%Reduced
Interchange Capital Partners, LLC16,813$31.4K0.01%−982−5.5%Reduced
Abel Hall, LLC16,491$30.8K0.01%+5,403+48.7%Added
Pathstone Holdings, LLC16,178$30.3K0.00%+132+0.8%Added
Mackenzie Financial Corp17,499$30.2K0.00%00.0%Unchanged
Sterling Capital Management LLC15,916$29.8K0.00%−3,137−16.5%Reduced
Mirae Asset Global Investments Co., Ltd.14,671$27.4K0.00%+3,059+26.3%Added
Zurcher Kantonalbank (Zurich Cantonalbank)13,582$25.4K0.00%−2,297−14.5%Reduced
Tactive Advisors, LLC13,097$24.5K0.01%−1,386−9.6%Reduced
Cim Investment Mangement Inc12,301$23.0K0.01%00.0%Unchanged
Quantinno Capital Management LP12,225$22.9K0.00%+12,225New
Principal Financial Group Inc12,115$22.7K0.00%−7,494−38.2%Reduced
Twin Lakes Capital Management, LLC11,557$21.6K0.01%00.0%Unchanged
GAMMA Investing LLC11,533$21.6K0.00%+11,533New
CIBC World Markets Inc.11,400$21.3K0.00%−18,600−62.0%Reduced
Horizon Kinetics Asset Management LLC11,034$20.6K0.00%−483−4.2%Reduced
Kingsview Wealth Management, LLC10,434$19.5K0.00%+10,434New
Verdence Capital Advisors LLC10,415$19.5K0.00%+10,415New
Caitong International Asset Management Co., Ltd10,371$19.4K0.00%−12,405−54.5%Reduced
HighTower Advisors, LLC10,103$18.9K0.00%−45−0.4%Reduced
DKM Wealth Management, Inc.10,000$18.7K0.01%+10,000New
FNY Investment Advisers, LLC10,000$18.0K0.01%−10,000−50.0%Reduced
Amalgamated Bank8,675$16.0K0.00%−766−8.1%Reduced
Tower Research Capital LLC (TRC)7,932$14.8K0.00%−82,983−91.3%Reduced
Federation des caisses Desjardins du Quebec7,500$14.0K0.00%−1,700−18.5%Reduced
Signaturefd, LLC7,467$14.0K0.00%+2,477+49.6%Added
State of Wyoming7,274$13.6K0.00%+7,274New
CWM, LLC6,203$12.0K0.00%+2,063+49.8%Added
GF Fund Management Co. Ltd.5,932$11.1K0.00%−530−8.2%Reduced
SBI Securities Co., Ltd.5,371$10.0K0.00%+1,793+50.1%Added
Allworth Financial LP4,051$7.58K0.00%−481−10.6%Reduced
Los Angeles Capital Management LLC3,590$6.96K0.00%+3,590New
Nisa Investment Advisors, LLC3,642$6.81K0.00%−2,578−41.4%Reduced
Parallel Advisors, LLC3,000$5.61K0.00%00.0%Unchanged
Hurley Capital, LLC2,976$5.57K0.00%+2,976New
Jones Financial Companies LLLP2,666$4.99K0.00%+2,666New
Quadrant Capital Group LLC2,554$4.78K0.00%+1,189+87.1%Added
Bryn Mawr Trust Co2,500$4.67K0.00%00.0%Unchanged
BOK Financial Private Wealth, Inc.2,500$4.67K0.00%+2,500New
SRS Capital Advisors, Inc.2,012$3.76K0.00%−1,085−35.0%Reduced
Louisbourg Investments Inc.1,900$3.55K0.00%+1,900New
Comerica Bank1,827$3.42K0.00%−169−8.5%Reduced
Dynamic Wealth Strategies, LLC1,678$3.14K0.00%00.0%Unchanged
Keating Financial Advisory Services, Inc.1,500$2.81K0.00%+1,500New
Rockefeller Capital Management L.P.1,246$2.33K0.00%+989+384.8%Added
Novem Group1,100$2.06K0.00%+1,100New
Daiwa Securities Group Inc.909$2.00K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC1,040$1.95K0.00%+181+21.1%Added
Caldwell Sutter Capital, Inc.950$1.78K0.00%00.0%Unchanged
UMA Financial Services, Inc.917$1.72K0.00%00.0%Unchanged
Fortitude Family Office, LLC793$1.48K0.00%00.0%Unchanged
Tidemark, LLC700$1.31K0.00%00.0%Unchanged
Smithfield Trust Co774$1.00K0.00%00.0%Unchanged
T. Rowe Price Investment Management, Inc.217$1.00K0.00%00.0%Unchanged
Farther Finance Advisors, LLC509$9520.00%+391+331.4%Added
Colonial Trust Advisors500$9350.00%00.0%Unchanged
Ancora Advisors, LLC430$8040.00%00.0%Unchanged
Cornerstone Financial Management LLC377$7050.00%+377New
US Bancorp303$5670.00%00.0%Unchanged
Global Retirement Partners, LLC283$5290.00%+168+146.1%Added
United Financial Planning Group LLC250$4680.00%+250New
VSM Wealth Advisory, LLC241$4510.00%00.0%Unchanged