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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q4 2025

Institutional positions in Pacific Biosciences of California, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
216
+12 vs. Q3 2025
Shares held
200.7M
+18.9M (+10.4%) vs. Q3 2025
Total value
$373.5M
+$141.3M (+60.8%) vs. Q3 2025
New holders
43
69 more added
Sold out
31
50 more reduced

4 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 216 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ4 2025: $373.5M
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q3 2025.

Institutions holding PACB in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Hantz Financial Services, Inc.4$00.00%00.0%Unchanged
Covestor Ltd43$00.00%−1−2.3%Reduced
Huntington National Bank1$20.00%00.0%Unchanged
Atlantic Union Bankshares Corp5$90.00%00.0%Unchanged
Nalls Sherbakoff Group, LLC16$300.00%00.0%Unchanged
The PNC Financial Services Group, Inc.23$430.00%00.0%Unchanged
Gen-Wealth Partners Inc70$1310.00%00.0%Unchanged
C M Bidwell & Associates Ltd96$1800.00%00.0%Unchanged
Northwestern Mutual Wealth Management Co100$1870.00%−3,900−97.5%Reduced
Medallion Wealth Advisors, LLC100$1870.00%00.0%Unchanged
DV Equities, LLC100$1870.00%+100New
Root Financial Partners, LLC100$1870.00%+100New
SageView Advisory Group, LLC103$1930.00%+103New
True Wealth Design, LLC104$1950.00%00.0%Unchanged
LRI Investments, LLC170$3180.00%+170New
Rothschild Investment LLC193$3610.00%+114+144.3%Added
VSM Wealth Advisory, LLC241$4510.00%00.0%Unchanged
United Financial Planning Group LLC250$4680.00%+250New
Global Retirement Partners, LLC283$5290.00%+168+146.1%Added
US Bancorp303$5670.00%00.0%Unchanged
Cornerstone Financial Management LLC377$7050.00%+377New
Ancora Advisors, LLC430$8040.00%00.0%Unchanged
Colonial Trust Advisors500$9350.00%00.0%Unchanged
Farther Finance Advisors, LLC509$9520.00%+391+331.4%Added
Smithfield Trust Co774$1.00K0.00%00.0%Unchanged
T. Rowe Price Investment Management, Inc.217$1.00K0.00%00.0%Unchanged
Tidemark, LLC700$1.31K0.00%00.0%Unchanged
Fortitude Family Office, LLC793$1.48K0.00%00.0%Unchanged
UMA Financial Services, Inc.917$1.72K0.00%00.0%Unchanged
Caldwell Sutter Capital, Inc.950$1.78K0.00%00.0%Unchanged
CIBC Private Wealth Group, LLC1,040$1.95K0.00%+181+21.1%Added
Daiwa Securities Group Inc.909$2.00K0.00%00.0%Unchanged
Novem Group1,100$2.06K0.00%+1,100New
Rockefeller Capital Management L.P.1,246$2.33K0.00%+989+384.8%Added
Keating Financial Advisory Services, Inc.1,500$2.81K0.00%+1,500New
Dynamic Wealth Strategies, LLC1,678$3.14K0.00%00.0%Unchanged
Comerica Bank1,827$3.42K0.00%−169−8.5%Reduced
Louisbourg Investments Inc.1,900$3.55K0.00%+1,900New
SRS Capital Advisors, Inc.2,012$3.76K0.00%−1,085−35.0%Reduced
Bryn Mawr Trust Co2,500$4.67K0.00%00.0%Unchanged
BOK Financial Private Wealth, Inc.2,500$4.67K0.00%+2,500New
Quadrant Capital Group LLC2,554$4.78K0.00%+1,189+87.1%Added
Jones Financial Companies LLLP2,666$4.99K0.00%+2,666New
Hurley Capital, LLC2,976$5.57K0.00%+2,976New
Parallel Advisors, LLC3,000$5.61K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC3,642$6.81K0.00%−2,578−41.4%Reduced
Los Angeles Capital Management LLC3,590$6.96K0.00%+3,590New
Allworth Financial LP4,051$7.58K0.00%−481−10.6%Reduced
SBI Securities Co., Ltd.5,371$10.0K0.00%+1,793+50.1%Added
GF Fund Management Co. Ltd.5,932$11.1K0.00%−530−8.2%Reduced
CWM, LLC6,203$12.0K0.00%+2,063+49.8%Added
State of Wyoming7,274$13.6K0.00%+7,274New
Signaturefd, LLC7,467$14.0K0.00%+2,477+49.6%Added
Federation des caisses Desjardins du Quebec7,500$14.0K0.00%−1,700−18.5%Reduced
Tower Research Capital LLC (TRC)7,932$14.8K0.00%−82,983−91.3%Reduced
Amalgamated Bank8,675$16.0K0.00%−766−8.1%Reduced
FNY Investment Advisers, LLC10,000$18.0K0.01%−10,000−50.0%Reduced
DKM Wealth Management, Inc.10,000$18.7K0.01%+10,000New
HighTower Advisors, LLC10,103$18.9K0.00%−45−0.4%Reduced
Caitong International Asset Management Co., Ltd10,371$19.4K0.00%−12,405−54.5%Reduced
Verdence Capital Advisors LLC10,415$19.5K0.00%+10,415New
Kingsview Wealth Management, LLC10,434$19.5K0.00%+10,434New
Horizon Kinetics Asset Management LLC11,034$20.6K0.00%−483−4.2%Reduced
CIBC World Markets Inc.11,400$21.3K0.00%−18,600−62.0%Reduced
GAMMA Investing LLC11,533$21.6K0.00%+11,533New
Twin Lakes Capital Management, LLC11,557$21.6K0.01%00.0%Unchanged
Principal Financial Group Inc12,115$22.7K0.00%−7,494−38.2%Reduced
Quantinno Capital Management LP12,225$22.9K0.00%+12,225New
Cim Investment Mangement Inc12,301$23.0K0.01%00.0%Unchanged
Tactive Advisors, LLC13,097$24.5K0.01%−1,386−9.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)13,582$25.4K0.00%−2,297−14.5%Reduced
Mirae Asset Global Investments Co., Ltd.14,671$27.4K0.00%+3,059+26.3%Added
Sterling Capital Management LLC15,916$29.8K0.00%−3,137−16.5%Reduced
Mackenzie Financial Corp17,499$30.2K0.00%00.0%Unchanged
Pathstone Holdings, LLC16,178$30.3K0.00%+132+0.8%Added
Abel Hall, LLC16,491$30.8K0.01%+5,403+48.7%Added
Interchange Capital Partners, LLC16,813$31.4K0.01%−982−5.5%Reduced
California State Teachers Retirement System16,998$31.8K0.00%−2,836−14.3%Reduced
Pinnacle Wealth Planning Services, Inc.17,849$33.4K0.00%+17,849New
Outlook Wealth Advisors, LLC18,000$33.7K0.01%+18,000New
CIBC World Markets Corp18,268$34.2K0.00%+18,268New
Great West Life Assurance Co20,280$38.0K0.00%+582+3.0%Added
SVB Capital Management, LLC20,586$38.5K1.38%00.0%Unchanged
Mercer Global Advisors Inc20,663$38.6K0.00%+6,695+47.9%Added
Ballentine Partners, LLC20,823$38.9K0.00%+4,342+26.3%Added
Neuberger Berman Group LLC21,435$40.1K0.00%+21,435New
Xponance, Inc.21,467$40.1K0.00%00.0%Unchanged
Engineers Gate Manager LP21,471$40.2K0.00%+21,471New
Wealth Enhancement Advisory Services, LLC19,337$40.2K0.00%+1,620+9.1%Added
Prime Capital Investment Advisors, LLC21,973$41.1K0.00%+166+0.8%Added
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors22,000$41.1K0.00%+22,000New
Prudential Financial Inc22,737$42.5K0.00%−12,947−36.3%Reduced
Cresset Asset Management, LLC22,955$42.9K0.00%00.0%Unchanged
Gallagher Fiduciary Advisors, LLC23,486$43.9K0.00%+1,813+8.4%Added
Russell Investments Group, Ltd.23,900$44.7K0.00%+1,029+4.5%Added
Private Advisor Group, LLC24,296$45.4K0.00%−4,323−15.1%Reduced
Legal & General Group Plc24,447$45.8K0.00%00.0%Unchanged
Royal Bank of Canada24,891$46.0K0.00%+1,633+7.0%Added
Private Wealth Partners, LLC25,000$46.8K0.00%+25,000New
Advisor Group Holdings, Inc.25,075$46.9K0.00%+4,877+24.1%Added