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Pacific Biosciences of California, Inc.

PACB
Exchange
Nasdaq
Industry
Laboratory Analytical Instruments
SEC CIK
0001299130

In the last 90 days, Pacific Biosciences of California, Inc. insiders filed 0 open-market purchases and 1 sale; 223 institutions reported holding it in 13F filings for Q2 2026, worth $320.8M in total; superinvestors ARK Invest and HHLR Advisors (Hillhouse) hold it.

13F holders, Q1 2022

Institutional positions in Pacific Biosciences of California, Inc. as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
250
−4 vs. Q4 2021
Shares held
223.1M
+17.8M (+8.7%) vs. Q4 2021
Total value
$2.03B
−$2.17B (−51.6%) vs. Q4 2021
New holders
44
93 more added
Sold out
48
70 more reduced

2 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PACB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 250 institutions
Q1 2021: 263 institutionsQ2 2021: 261 institutionsQ3 2021: 246 institutionsQ4 2021: 256 institutionsQ1 2022: 250 institutionsQ2 2022: 230 institutionsQ3 2022: 227 institutionsQ4 2022: 237 institutionsQ1 2023: 260 institutionsQ2 2023: 272 institutionsQ3 2023: 275 institutionsQ4 2023: 274 institutionsQ1 2024: 268 institutionsQ2 2024: 229 institutionsQ3 2024: 226 institutionsQ4 2024: 227 institutionsQ1 2025: 225 institutionsQ2 2025: 207 institutionsQ3 2025: 208 institutionsQ4 2025: 216 institutionsQ1 2026: 231 institutionsQ2 2026: 223 institutions
Value heldQ1 2022: $2.03B
Q1 2021: $5.47BQ2 2021: $6.04BQ3 2021: $4.83BQ4 2021: $4.20BQ1 2022: $2.03BQ2 2022: $1.03BQ3 2022: $1.23BQ4 2022: $1.84BQ1 2023: $2.93BQ2 2023: $3.37BQ3 2023: $2.20BQ4 2023: $2.76BQ1 2024: $1.01BQ2 2024: $331.9MQ3 2024: $394.3MQ4 2024: $475.1MQ1 2025: $265.6MQ2 2025: $245.8MQ3 2025: $237.8MQ4 2025: $373.5MQ1 2026: $248.5MQ2 2026: $320.8M
Institutions holding PACB and their total value by quarter
QuarterHoldersValue
Q2 2026223$320.8M
Q1 2026231$248.5M
Q4 2025216$373.5M
Q3 2025208$237.8M
Q2 2025207$245.8M
Q1 2025225$265.6M
Q4 2024227$475.1M
Q3 2024226$394.3M
Q2 2024229$331.9M
Q1 2024268$1.01B
Q4 2023274$2.76B
Q3 2023275$2.20B
Q2 2023272$3.37B
Q1 2023260$2.93B
Q4 2022237$1.84B
Q3 2022227$1.23B
Q2 2022230$1.03B
Q1 2022250$2.03B
Q4 2021256$4.20B
Q3 2021246$4.83B
Q2 2021261$6.04B
Q1 2021263$5.47B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Pacific Biosciences of California, Inc.; share changes are against Q4 2021.

Institutions holding PACB in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
ARK Investment Management LLCSuperinvestorARK Invest27,259,521$248.1M1.04%+876,418+3.3%Added
Jackson Square Partners, LLC22,542,589$205.1M2.04%+8,039,420+55.4%Added
Vanguard Group Inc19,945,092$181.5M0.00%+90,216+0.5%Added
BlackRock Inc.16,609,353$151.1M0.00%+40,109+0.2%Added
Nikko Asset Management Americas, Inc.14,021,205$127.9M0.94%+2,106,180+17.7%Added
Sumitomo Mitsui Trust Holdings, Inc.14,021,205$127.6M0.08%+2,106,180+17.7%Added
Capital International Investors12,781,855$116.3M0.03%+675,537+5.6%Added
Casdin Capital, LLC7,990,652$72.7M3.26%00.0%Unchanged
Price T Rowe Associates Inc6,104,093$55.5M0.01%+270,289+4.6%Added
Baker Bros. Advisors LP5,444,963$49.5M0.28%00.0%Unchanged
Bellevue Group AG4,881,752$44.4M0.52%+3,328,729+214.3%Added
State Street Corp4,428,965$40.3M0.00%+271,315+6.5%Added
SEI Investments Co3,936,287$35.8M0.07%+1,261,333+47.2%Added
Geode Capital Management, LLC3,842,564$35.0M0.00%+138,571+3.7%Added
Macquarie Group Ltd3,841,026$35.0M0.03%+1,941,270+102.2%Added
Capital World Investors3,390,000$30.8M0.01%00.0%Unchanged
Two Sigma Investments, LP3,088,155$28.1M0.08%+2,699,194+693.9%Added
Goldman Sachs Group Inc2,904,619$26.4M0.01%+228,964+8.6%Added
Blue Water Life Science Advisors, LLC2,660,000$24.2M11.49%+2,660,000New
Millennium Management LLC2,436,902$22.2M0.03%+1,978,498+431.6%Added
Citadel Advisors LLC2,248,249$20.5M0.02%+1,893,895+534.5%Added
Northern Trust Corp1,979,768$18.0M0.00%−4,190−0.2%Reduced
Morgan Stanley1,948,642$17.7M0.00%+840,967+75.9%Added
SB Management Ltd1,886,107$17.2M3.35%−6,270,000−76.9%Reduced
Farallon Capital Management, L.L.C.1,631,800$14.8M0.08%−413,688−20.2%Reduced
Charles Schwab Investment Management Inc1,627,942$14.8M0.00%+36,617+2.3%Added
FMR LLC1,479,433$13.5M0.00%−312,858−17.5%Reduced
Decheng Capital Management III (Cayman), LLC1,463,872$13.3M4.08%+1,463,872New
Norges Bank1,281,967$11.7M0.00%−444,602−25.8%Reduced
Oracle Investment Management Inc1,225,395$11.2M2.24%−195,257−13.7%Reduced
Nuveen Asset Management, LLC1,070,303$10.6M0.00%−102,415−8.7%Reduced
Two Sigma Advisers, LP1,088,300$9.90M0.03%+705,900+184.6%Added
JPMorgan Chase & Co1,015,819$9.24M0.00%+748,630+280.2%Added
Bank of New York Mellon Corp997,044$9.07M0.00%−9,695−1.0%Reduced
Renaissance Technologies LLC868,700$7.91M0.01%+868,700New
Voloridge Investment Management, LLC846,180$7.70M0.04%+846,180New
Squarepoint Ops LLC819,470$7.46M0.06%+800,175+4,147.1%Added
D. E. Shaw & Co., Inc.722,527$6.58M0.01%−461,687−39.0%Reduced
WCM Investment Management, LLC679,803$6.19M0.02%+341,557+101.0%Added
Cubist Systematic Strategies, LLC622,494$5.67M0.05%+577,366+1,279.4%Added
Bank of America Corp593,831$5.40M0.00%+137,847+30.2%Added
Bourne Lent Asset Management Inc556,865$5.07M1.59%+1,115+0.2%Added
Swiss National Bank495,546$4.51M0.00%+80,000+19.3%Added
Polar Asset Management Partners Inc.476,500$4.34M0.05%+476,500New
Guggenheim Capital LLC450,108$4.10M0.02%+31,330+7.5%Added
Granahan Investment Management Inc412,183$3.75M0.09%−76,712−15.7%Reduced
Engineers Gate Manager LP402,217$3.66M0.14%+389,169+2,982.6%Added
Banque Pictet & Cie SA400,722$3.65M0.03%−3,634−0.9%Reduced
Mirae Asset Global Investments Co., Ltd.377,270$3.43M0.01%−68,930−15.4%Reduced
Twinbeech Capital LP320,159$2.91M0.13%+320,159New
California Public Employees Retirement System307,737$2.80M0.00%−76,804−20.0%Reduced
Deutsche Bank AG302,301$2.75M0.00%−21,993−6.8%Reduced
UBS Asset Management Americas Inc286,838$2.61M0.00%+68,448+31.3%Added
Cantor Fitzgerald, L. P.275,000$2.50M0.19%+275,000New
TD Asset Management Inc268,658$2.44M0.00%+31,223+13.2%Added
Natixis262,858$2.39M0.01%−798,838−75.2%Reduced
California State Teachers Retirement System261,613$2.38M0.00%−4,393−1.7%Reduced
Manufacturers Life Insurance Company, The246,142$2.33M0.00%+147,698+150.0%Added
State of Wisconsin Investment Board249,900$2.27M0.00%00.0%Unchanged
Credit Suisse AG246,254$2.24M0.00%+37,207+17.8%Added
Alliancebernstein L.P.244,800$2.23M0.00%+600+0.2%Added
State of New Jersey Common Pension Fund D244,882$2.23M0.01%+129,084+111.5%Added
Rhumbline Advisers236,802$2.15M0.00%−8,272−3.4%Reduced
Harvard Management Co Inc229,144$2.08M0.21%00.0%Unchanged
Jump Financial, LLC218,838$1.99M0.08%+129,504+145.0%Added
HighTower Advisors, LLC208,655$1.90M0.00%+117,770+129.6%Added
Gabelli Funds LLC203,000$1.85M0.01%00.0%Unchanged
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.183,126$1.67M0.01%−6,719−3.5%Reduced
Legal & General Group Plc171,807$1.56M0.00%+4,155+2.5%Added
Data Collective II GP, LLC164,249$1.50M5.44%00.0%Unchanged
Barclays PLC160,814$1.46M0.00%−157,996−49.6%Reduced
Seven Eight Capital, LP157,308$1.43M0.19%+73,819+88.4%Added
Nan Fung Group Holdings Ltd144,840$1.32M0.63%−26,920−15.7%Reduced
Parametric Portfolio Associates LLC144,751$1.32M0.00%+21,010+17.0%Added
Abacus Planning Group, Inc.140,000$1.27M0.34%−15,000−9.7%Reduced
New York State Common Retirement Fund136,715$1.24M0.00%−190.0%Reduced
LPL Financial LLC131,230$1.19M0.00%+30,597+30.4%Added
Pictet Asset Management SA130,720$1.19M0.00%00.0%Unchanged
HRT Financial LP129,950$1.18M0.01%+129,950New
Vontobel Holding Ltd.115,645$1.12M0.01%+23,693+25.8%Added
Wells Fargo & Company117,488$1.07M0.00%−98,451−45.6%Reduced
Echo Street Capital Management LLC114,997$1.05M0.01%+114,997New
Reynders McVeigh Capital Management, LLC113,480$1.03M0.06%−31,970−22.0%Reduced
Mutual of America Capital Management LLC111,798$1.02M0.01%−4,861−4.2%Reduced
Raymond James & Associates111,686$1.02M0.00%+813+0.7%Added
Invesco Ltd.111,283$1.01M0.00%−3,084,507−96.5%Reduced
Qube Research & Technologies Ltd110,092$1.00M0.01%+110,092New
MetLife Investment Management103,966$946.1K0.01%+34,699+50.1%Added
Shelton Capital Management100,000$910.0K0.03%−35,000−25.9%Reduced
NJ State Employees Deferred Compensation Plan100,000$910.0K0.12%00.0%Unchanged
UBS Group AG97,222$885.0K0.00%−2,760−2.8%Reduced
HSBC Holdings PLC96,953$883.0K0.00%+53,919+125.3%Added
American International Group, Inc.96,553$879.0K0.00%−6,796−6.6%Reduced
Stifel Financial Corp90,569$824.0K0.00%+25,316+38.8%Added
Hall Laurie J Trustee88,185$803.0K0.31%+88,185New
Jennison Associates LLC82,216$748.0K0.00%+82,216New
Voya Investment Management LLC81,545$742.0K0.00%+4,447+5.8%Added
DekaBank Deutsche Girozentrale73,300$707.0K0.00%+6,700+10.1%Added
Dynamic Technology Lab Private Ltd77,696$707.0K0.08%+77,696New
Jane Street Group, LLC77,472$705.0K0.00%−141,218−64.6%Reduced