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OnKure Therapeutics, Inc.

OKUR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001637715

In the last 90 days, OnKure Therapeutics, Inc. insiders filed 0 open-market purchases and 2 sales; 75 institutions reported holding it in 13F filings for Q2 2026, worth $159.0M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in OnKure Therapeutics, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
47
−4 vs. Q4 2024
Shares held
11.9M
+105.9K (+0.9%) vs. Q4 2024
Total value
$50.1M
−$49.1M (−49.5%) vs. Q4 2024
New holders
4
15 more added
Sold out
8
13 more reduced

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting OKUR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 47 institutions
Q1 2021: 0 institutionsQ2 2021: 38 institutionsQ3 2021: 38 institutionsQ4 2021: 39 institutionsQ1 2022: 41 institutionsQ2 2022: 33 institutionsQ3 2022: 33 institutionsQ4 2022: 32 institutionsQ1 2023: 35 institutionsQ2 2023: 52 institutionsQ3 2023: 58 institutionsQ4 2023: 68 institutionsQ1 2024: 62 institutionsQ2 2024: 66 institutionsQ3 2024: 51 institutionsQ4 2024: 51 institutionsQ1 2025: 47 institutionsQ2 2025: 49 institutionsQ3 2025: 42 institutionsQ4 2025: 44 institutionsQ1 2026: 51 institutionsQ2 2026: 75 institutions
Value heldQ1 2025: $50.1M
Q1 2021: $0Q2 2021: $170.6MQ3 2021: $136.7MQ4 2021: $148.9MQ1 2022: $50.8MQ2 2022: $43.3MQ3 2022: $55.1MQ4 2022: $38.4MQ1 2023: $102.0MQ2 2023: $168.9MQ3 2023: $208.3MQ4 2023: $40.4MQ1 2024: $45.4MQ2 2024: $41.3MQ3 2024: $49.0MQ4 2024: $99.2MQ1 2025: $50.1MQ2 2025: $25.8MQ3 2025: $28.1MQ4 2025: $32.0MQ1 2026: $113.9MQ2 2026: $159.0M
Institutions holding OKUR and their total value by quarter
QuarterHoldersValue
Q2 202675$159.0M
Q1 202651$113.9M
Q4 202544$32.0M
Q3 202542$28.1M
Q2 202549$25.8M
Q1 202547$50.1M
Q4 202451$99.2M
Q3 202451$49.0M
Q2 202466$41.3M
Q1 202462$45.4M
Q4 202368$40.4M
Q3 202358$208.3M
Q2 202352$168.9M
Q1 202335$102.0M
Q4 202232$38.4M
Q3 202233$55.1M
Q2 202233$43.3M
Q1 202241$50.8M
Q4 202139$148.9M
Q3 202138$136.7M
Q2 202138$170.6M
Q1 20210$0

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding OnKure Therapeutics, Inc.; share changes are against Q4 2024.

Institutions holding OKUR in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Royal Bank of Canada32$00.00%−11−25.6%Reduced
MAI Capital Management6$260.00%00.0%Unchanged
Group One Trading, L.P.56$2410.00%−233−80.6%Reduced
Citigroup Inc190$8180.00%+88+86.3%Added
Bank of America Corp221$9500.00%−249,421−99.9%Reduced
JPMorgan Chase & Co231$9930.00%−106−31.5%Reduced
UBS Group AG280$1.20K0.00%−1,933−87.3%Reduced
BNP Paribas Arbitrage, SA297$1.28K0.00%+61+25.8%Added
GF Fund Management Co. Ltd.313$1.35K0.00%+47+17.7%Added
Mirae Asset Global Investments Co., Ltd.423$1.89K0.00%+1+0.2%Added
Morgan Stanley1,878$8.08K0.00%+946+101.5%Added
Tower Research Capital LLC (TRC)2,224$9.56K0.00%+23+1.0%Added
China Universal Asset Management Co., Ltd.2,538$10.9K0.00%−145−5.4%Reduced
Wells Fargo & Company3,620$15.6K0.00%+2,000+123.5%Added
Barclays PLC6,765$29.1K0.00%−1,976−22.6%Reduced
ADAR1 Capital Management, LLC10,000$43.0K0.01%+10,000New
Qube Research & Technologies Ltd18,663$80.3K0.00%+18,663New
Northern Trust Corp19,177$82.5K0.00%00.0%Unchanged
Bridgeway Capital Management, LLC25,000$107.5K0.00%+25,000New
Two Sigma Investments, LP27,148$116.7K0.00%+27,148New
Two Sigma Advisers, LP27,628$118.8K0.00%+13,400+94.2%Added
Renaissance Technologies LLC41,863$180.0K0.00%−5,587−11.8%Reduced
Aldebaran Capital, LLC45,048$193.7K0.18%−524−1.1%Reduced
Nantahala Capital Management, LLC54,208$233.1K0.02%−569−1.0%Reduced
Boothbay Fund Management, LLC78,021$335.5K0.01%00.0%Unchanged
Sphera Funds Management Ltd.80,454$346.0K0.09%−6,900−7.9%Reduced
Geode Capital Management, LLC86,311$371.2K0.00%+9,712+12.7%Added
Aisling Capital Management LP88,607$381.0K0.13%00.0%Unchanged
BlackRock, Inc.88,981$382.6K0.00%−5,036−5.4%Reduced
Cantor Fitzgerald, L. P.130,700$562.0K0.02%+95,000+266.1%Added
Shay Capital LLC151,038$649.5K0.19%+136,022+905.8%Added
Prosight Management, LP186,570$802.3K0.26%+122,816+192.6%Added
Ikarian Capital, LLC253,754$1.09M0.36%00.0%Unchanged
Carlyle Group Inc.269,895$1.16M0.03%00.0%Unchanged
Affinity Asset Advisors, LLC394,159$1.69M0.27%+250,000+173.4%Added
Tang Capital Management LLC400,000$1.72M0.10%+105,374+35.8%Added
Highbridge Capital Management LLC438,797$1.89M0.08%+39,054+9.8%Added
NEA Management Company, LLC478,548$2.06M0.16%00.0%Unchanged
StepStone Group LP491,938$2.12M2.17%00.0%Unchanged
Deep Track Capital, LP523,989$2.25M0.07%00.0%Unchanged
Vestal Point Capital, LP635,000$2.73M0.19%00.0%Unchanged
Vanguard Group Inc706,733$3.04M0.00%00.0%Unchanged
Samsara BioCapital, LLC824,155$3.54M0.63%00.0%Unchanged
Perceptive Advisors LLC1,004,439$4.32M0.15%00.0%Unchanged
Citadel Advisors LLC1,068,104$4.44M0.00%−6,210−0.6%Reduced
Acorn Capital Advisors, LLC1,439,674$5.12M3.42%00.0%Unchanged
Cormorant Asset Management, LP1,837,739$7.90M0.60%00.0%Unchanged
Altium Capital Management LP0$00.00%−218,386−100.0%Sold out
Millennium Management LLC0$00.00%−144,099−100.0%Sold out
683 Capital Management, LLC0$00.00%−43,371−100.0%Sold out
Cubist Systematic Strategies, LLC0$00.00%−20,549−100.0%Sold out
XTX Topco Ltd0$00.00%−18,633−100.0%Sold out
Walleye Capital LLC0$00.00%−13,495−100.0%Sold out
Omers Administration Corp0$00.00%−12,100−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−152−100.0%Sold out