Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Mineralys Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 223
- +32 vs. Q3 2025
- Shares held
- 88.4M
- +9.06M (+11.4%) vs. Q3 2025
- Total value
- $3.21B
- +$199.8M (+6.6%) vs. Q3 2025
- New holders
- 52
- 82 more added
- Sold out
- 20
- 72 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Moore Capital Management, LP | 60,000 | $2.18M | 0.04% | −105,000−63.6% | Reduced |
| Zimmer Partners, LP | 57,500 | $2.09M | 0.05% | −42,500−42.5% | Reduced |
| Wells Fargo & Company | 56,756 | $2.06M | 0.00% | +26,702+88.8% | Added |
| Rhumbline Advisers | 54,284 | $1.97M | 0.00% | −1,007−1.8% | Reduced |
| Findell Capital Management LLC | 50,000 | $1.81M | 0.60% | −200,000−80.0% | Reduced |
| State of Wisconsin Investment Board | 49,941 | $1.81M | 0.00% | +23,015+85.5% | Added |
| Schonfeld Strategic Advisors LLC | 49,821 | $1.81M | 0.01% | +35,203+240.8% | Added |
| PFM Health Sciences, LP | 47,637 | $1.73M | 0.18% | +47,637 | New |
| Algert Global LLC | 47,500 | $1.72M | 0.03% | 00.0% | Unchanged |
| J. Goldman & Co LP | 47,288 | $1.72M | 0.07% | +3,420+7.8% | Added |
| Profund Advisors LLC | 47,024 | $1.71M | 0.05% | +39,768+548.1% | Added |
| JPMorgan Chase & Co | 46,683 | $1.69M | 0.00% | −136,997−74.6% | Reduced |
| Ameriprise Financial Inc | 46,246 | $1.68M | 0.00% | −50,901−52.4% | Reduced |
| Erste Asset Management GmbH | 45,000 | $1.66M | 0.01% | 00.0% | Unchanged |
| Legal & General Group Plc | 43,938 | $1.59M | 0.00% | −1,491−3.3% | Reduced |
| California State Teachers Retirement System | 43,348 | $1.57M | 0.00% | +6,749+18.4% | Added |
| Seven Fleet Capital Management LP | 42,025 | $1.53M | 1.03% | +42,025 | New |
| Tudor Investment Corp Et Al | 39,046 | $1.42M | 0.01% | +39,046 | New |
| DAFNA Capital Management LLC | 38,490 | $1.40M | 0.32% | −45,000−53.9% | Reduced |
| Deutsche Bank AG | 37,245 | $1.35M | 0.00% | +6,315+20.4% | Added |
| HRT Financial LP | 37,236 | $1.35M | 0.00% | −96,802−72.2% | Reduced |
| Victory Capital Management Inc | 32,881 | $1.19M | 0.00% | +27,174+476.2% | Added |
| Sectoral Asset Management Inc | 31,625 | $1.15M | 0.92% | −2,260−6.7% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 31,359 | $1.14M | 0.03% | −5,014−13.8% | Reduced |
| Allianz Asset Management GmbH | 30,200 | $1.10M | 0.00% | −3,500−10.4% | Reduced |
| Canada Pension Plan Investment Board | 29,600 | $1.07M | 0.00% | +29,600 | New |
| Invesco Ltd. | 29,141 | $1.06M | 0.00% | −158,845−84.5% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 29,182 | $1.05M | 0.00% | +9,466+48.0% | Added |
| MetLife Investment Management | 26,005 | $943.7K | 0.00% | +3,296+14.5% | Added |
| CenterBook Partners LP | 26,000 | $943.5K | 0.05% | +26,000 | New |
| Diadema Partners LP | 25,000 | $907.3K | 0.54% | +25,000 | New |
| Raymond James Financial Inc | 24,974 | $906.3K | 0.00% | +24,974 | New |
| Sigma Planning Corp | 24,000 | $871.0K | 0.02% | +24,000 | New |
| Atom Investors LP | 22,330 | $810.4K | 0.06% | +22,330 | New |
| Creative Planning | 21,103 | $765.8K | 0.00% | −1,192−5.3% | Reduced |
| Maven Securities LTD | 20,000 | $725.8K | 0.09% | +20,000 | New |
| Bellevue Group AG | 19,826 | $719.5K | 0.01% | −6,779−25.5% | Reduced |
| Citigroup Inc | 18,315 | $664.7K | 0.00% | −144,853−88.8% | Reduced |
| Quantinno Capital Management LP | 18,243 | $662.0K | 0.00% | −384−2.1% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 17,348 | $629.6K | 0.00% | −4,970−22.3% | Reduced |
| Twin Securities, Inc. | 16,737 | $607.4K | 0.23% | +16,737 | New |
| Intech Investment Management LLC | 16,723 | $606.9K | 0.01% | +16,723 | New |
| Manufacturers Life Insurance Company, The | 16,181 | $587.2K | 0.00% | +1,415+9.6% | Added |
| Entropy Technologies, LP | 16,175 | $587.0K | 0.03% | +16,175 | New |
| State of New Jersey Common Pension Fund D | 15,584 | $565.5K | 0.00% | +15,584 | New |
| PSP Research LLC | 14,818 | $537.7K | 0.47% | +14,818 | New |
| Fox Run Management, L.L.C. | 14,526 | $527.1K | 0.08% | +14,526 | New |
| Campbell & CO Investment Adviser LLC | 14,404 | $522.7K | 0.03% | +14,404 | New |
| Handelsbanken Fonder AB | 14,100 | $512.0K | 0.00% | +14,100 | New |
| Arizona State Retirement System | 13,000 | $471.8K | 0.00% | +2,393+22.6% | Added |
| China Universal Asset Management Co., Ltd. | 12,896 | $468.0K | 0.04% | +1,275+11.0% | Added |
| Police & Firemen's Retirement System of New Jersey | 12,683 | $460.3K | 0.00% | +1,717+15.7% | Added |
| New York State Common Retirement Fund | 12,564 | $455.9K | 0.00% | 00.0% | Unchanged |
| Optimize Financial Inc | 12,383 | $449.4K | 0.23% | +176+1.4% | Added |
| ProShare Advisors LLC | 12,040 | $436.9K | 0.00% | +2,985+33.0% | Added |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 11,997 | $435.4K | 0.00% | +11,997 | New |
| Quest Partners LLC | 11,328 | $411.1K | 0.02% | −1,277−10.1% | Reduced |
| FORA Capital, LLC | 11,050 | $401.0K | 0.05% | +4,725+74.7% | Added |
| Change Path, LLC | 10,750 | $390.1K | 0.01% | 00.0% | Unchanged |
| Lion Point Capital, LP | 10,500 | $381.0K | 1.97% | −28,500−73.1% | Reduced |
| Pale Fire Capital SE | 10,354 | $375.7K | 0.05% | −522,053−98.1% | Reduced |
| Mariner, LLC | 10,230 | $371.5K | 0.00% | −6,179−37.7% | Reduced |
| KLP Kapitalforvaltning AS | 9,600 | $348.4K | 0.00% | +2,900+43.3% | Added |
| Virginia Retirement Systems Et Al | 9,350 | $339.3K | 0.00% | +9,350 | New |
| SEI Investments Co | 8,780 | $318.6K | 0.00% | −1,085−11.0% | Reduced |
| State Board of Administration of Florida Retirement System | 7,561 | $274.4K | 0.00% | 00.0% | Unchanged |
| Banque Pictet & Cie SA | 7,486 | $271.7K | 0.00% | +7,486 | New |
| Persistent Asset Partners Ltd | 7,416 | $269.1K | 0.13% | +7,416 | New |
| Virtus Investment Advisers, Inc. | 7,209 | $261.6K | 0.07% | −417−5.5% | Reduced |
| Kingswood Wealth Advisors, LLC | 7,074 | $256.7K | 0.01% | −9,069−56.2% | Reduced |
| Cinctive Capital Management LP | 7,037 | $255.4K | 0.01% | −64,676−90.2% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 6,860 | $248.9K | 0.00% | −7,389−51.9% | Reduced |
| Teacher Retirement System of Texas | 6,781 | $246.1K | 0.00% | −2,905−30.0% | Reduced |
| NEOS Investment Management LLC | 6,463 | $234.5K | 0.00% | +6,463 | New |
| Tema ETFs LLC | 6,463 | $234.5K | 0.02% | +6,463 | New |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 6,384 | $231.7K | 0.03% | +6,384 | New |
| CWM, LLC | 5,098 | $185.0K | 0.00% | −499−8.9% | Reduced |
| Simplex Trading, LLC | 4,802 | $174.3K | 0.00% | +379+8.6% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,846 | $139.6K | 0.00% | +1,283+50.1% | Added |
| Caitong International Asset Management Co., Ltd | 3,823 | $138.7K | 0.03% | +3,715+3,439.8% | Added |
| Ameritas Investment Partners, Inc. | 3,798 | $137.8K | 0.00% | +529+16.2% | Added |
| Acadian Asset Management LLC | 2,908 | $104.0K | 0.00% | +2,908 | New |
| The PNC Financial Services Group, Inc. | 2,234 | $81.1K | 0.00% | 00.0% | Unchanged |
| Nisa Investment Advisors, LLC | 1,949 | $70.7K | 0.00% | −116−5.6% | Reduced |
| GF Fund Management Co. Ltd. | 1,555 | $56.4K | 0.00% | +129+9.0% | Added |
| Royal Bank of Canada | 1,529 | $56.0K | 0.00% | +1,107+262.3% | Added |
| Amalgamated Bank | 1,470 | $53.0K | 0.00% | +485+49.2% | Added |
| Advisor Group Holdings, Inc. | 1,155 | $41.9K | 0.00% | −27,369−96.0% | Reduced |
| Smartleaf Asset Management LLC | 1,003 | $35.6K | 0.00% | −14−1.4% | Reduced |
| Navalign, LLC | 900 | $32.7K | 0.01% | +900 | New |
| Comerica Bank | 781 | $28.3K | 0.00% | +1+0.1% | Added |
| Tower Research Capital LLC (TRC) | 520 | $18.9K | 0.00% | −2,851−84.6% | Reduced |
| Versant Capital Management, Inc | 513 | $18.6K | 0.00% | 00.0% | Unchanged |
| Covestor Ltd | 473 | $17.0K | 0.01% | −94−16.6% | Reduced |
| GAMMA Investing LLC | 451 | $16.4K | 0.00% | +15+3.4% | Added |
| Pinnacle Wealth Planning Services, Inc. | 355 | $12.9K | 0.00% | +355 | New |
| Massmutual Trust Co FSB | 319 | $11.6K | 0.00% | 00.0% | Unchanged |
| Los Angeles Capital Management LLC | 275 | $11.3K | 0.00% | +275 | New |
| Sterling Capital Management LLC | 306 | $11.1K | 0.00% | +211+222.1% | Added |
| Daiwa Securities Group Inc. | 235 | $9.00K | 0.00% | +36+18.1% | Added |