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Mineralys Therapeutics, Inc.

MLYS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001933414

In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Mineralys Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
223
+32 vs. Q3 2025
Shares held
88.4M
+9.06M (+11.4%) vs. Q3 2025
Total value
$3.21B
+$199.8M (+6.6%) vs. Q3 2025
New holders
52
82 more added
Sold out
20
72 more reduced

2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 223 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 68 institutionsQ2 2023: 68 institutionsQ3 2023: 77 institutionsQ4 2023: 87 institutionsQ1 2024: 92 institutionsQ2 2024: 94 institutionsQ3 2024: 106 institutionsQ4 2024: 109 institutionsQ1 2025: 149 institutionsQ2 2025: 166 institutionsQ3 2025: 193 institutionsQ4 2025: 223 institutionsQ1 2026: 215 institutionsQ2 2026: 225 institutions
Value heldQ4 2025: $3.21B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $385.4MQ2 2023: $429.2MQ3 2023: $252.1MQ4 2023: $298.5MQ1 2024: $540.6MQ2 2024: $516.6MQ3 2024: $540.1MQ4 2024: $572.2MQ1 2025: $966.2MQ2 2025: $888.8MQ3 2025: $3.01BQ4 2025: $3.21BQ1 2026: $2.46BQ2 2026: $2.69B
Institutions holding MLYS and their total value by quarter
QuarterHoldersValue
Q2 2026225$2.69B
Q1 2026215$2.46B
Q4 2025223$3.21B
Q3 2025193$3.01B
Q2 2025166$888.8M
Q1 2025149$966.2M
Q4 2024109$572.2M
Q3 2024106$540.1M
Q2 202494$516.6M
Q1 202492$540.6M
Q4 202387$298.5M
Q3 202377$252.1M
Q2 202368$429.2M
Q1 202368$385.4M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q3 2025.

Institutions holding MLYS in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Allworth Financial LP219$7.95K0.00%+175+397.7%Added
Larson Financial Group LLC154$5.59K0.00%+124+413.3%Added
EverSource Wealth Advisors, LLC154$5.59K0.00%+2+1.3%Added
Rockefeller Capital Management L.P.134$4.86K0.00%+103+332.3%Added
SBI Securities Co., Ltd.116$4.21K0.00%−1,010−89.7%Reduced
SRS Capital Advisors, Inc.109$3.96K0.00%−161−59.6%Reduced
US Bancorp81$2.94K0.00%−123−60.3%Reduced
J.Safra Asset Management Corp81$2.94K0.00%+81New
True Wealth Design, LLC76$2.76K0.00%00.0%Unchanged
Rothschild Investment LLC55$2.00K0.00%+5+10.0%Added
Optiver Holding B.V.42$1.52K0.00%−244−85.3%Reduced
Torren Management, LLC39$1.42K0.00%+39New
Parkside Financial Bank & Trust35$1.27K0.00%00.0%Unchanged
Farther Finance Advisors, LLC35$1.27K0.00%+2+6.1%Added
Private Wealth Management Group, LLC28$1.02K0.00%−22−44.0%Reduced
Bessemer Group Inc38$1.00K0.00%+38New
MAI Capital Management24$8710.00%+6+33.3%Added
Parallel Advisors, LLC22$7980.00%00.0%Unchanged
Clearstead Advisors, LLC11$4000.00%+11New
Quadrant Capital Group LLC8$2910.00%−2−20.0%Reduced
IFP Advisors, Inc8$2900.00%+6+300.0%Added
Essential Partners LLC1$360.00%00.0%Unchanged
Avion Wealth21$00.00%−57−73.1%Reduced
Nearwater Capital Markets, Ltd0$00.00%−450,000−100.0%Sold out
Tang Capital Management LLC0$00.00%−200,000−100.0%Sold out
Atika Capital Management LLC0$00.00%−174,000−100.0%Sold out
Jain Global LLC0$00.00%−120,854−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−105,000−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−75,768−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−42,276−100.0%Sold out
Resolute Capital Asset Partners LLC0$00.00%−40,000−100.0%Sold out
Jane Street Group, LLC0$00.00%−37,145−100.0%Sold out
Mark Asset Management LP0$00.00%−19,465−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−15,268−100.0%Sold out
Caption Management, LLC0$00.00%−13,000−100.0%Sold out
Oxford Asset Management LLP0$00.00%−9,123−100.0%Sold out
Scientech Research LLC0$00.00%−7,964−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−6,670−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−6,338−100.0%Sold out
Letko, Brosseau & Associates Inc0$00.00%−5,475−100.0%Sold out
Quantbot Technologies LP0$00.00%−39−100.0%Sold out
Rise Advisors, LLC0$00.00%−37−100.0%Sold out
Federated Hermes, Inc.0$00.00%−21−100.0%Sold out
Point72 (DIFC) Ltd––––Not filed
FSA Wealth Management LLC––––Not filed