Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 12 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Mineralys Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 193
- +27 vs. Q2 2025
- Shares held
- 79.3M
- +13.6M (+20.8%) vs. Q2 2025
- Total value
- $3.01B
- +$2.12B (+238.4%) vs. Q2 2025
- New holders
- 42
- 69 more added
- Sold out
- 15
- 63 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 67 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Catalys Pacific, LLC | 8,903,838 | $337.6M | 96.09% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 7,323,750 | $277.7M | 3.42% | +1,176,470+19.1% | Added |
| Samsara BioCapital, LLC | 6,263,151 | $237.5M | 31.01% | +588,235+10.4% | Added |
| BlackRock, Inc. | 3,671,614 | $139.2M | 0.00% | +573,854+18.5% | Added |
| Vanguard Group Inc | 3,018,999 | $114.5M | 0.00% | +692,550+29.8% | Added |
| Caligan Partners LP | 2,772,654 | $105.1M | 14.59% | +755,302+37.4% | Added |
| Capital International Investors | 2,393,396 | $90.8M | 0.01% | −505,624−17.4% | Reduced |
| Suvretta Capital Management, LLC | 2,132,133 | $80.9M | 2.45% | +387,641+22.2% | Added |
| Sr One Capital Management, LP | 2,113,933 | $80.2M | 11.59% | −1,014,000−32.4% | Reduced |
| FMR LLC | 2,071,255 | $78.5M | 0.00% | +1,766,369+579.4% | Added |
| Citadel Advisors LLC | 2,067,227 | $78.4M | 0.06% | +2,052,845+14,273.7% | Added |
| Franklin Resources Inc | 1,809,768 | $68.6M | 0.02% | +6,171+0.3% | Added |
| Point72 Asset Management, L.P. | 1,799,628 | $68.2M | 0.15% | +1,799,628 | New |
| Laurion Capital Management LP | 1,720,445 | $65.2M | 8.90% | −42,137−2.4% | Reduced |
| Farallon Capital Management, L.L.C. | 1,673,053 | $63.4M | 0.36% | +1,673,053 | New |
| Integral Health Asset Management, LLC | 1,500,000 | $56.9M | 4.15% | −1,200,000−44.4% | Reduced |
| OrbiMed Advisors LLC | 1,469,494 | $55.7M | 1.34% | +709,143+93.3% | Added |
| Morgan Stanley | 1,376,998 | $52.2M | 0.00% | +789,168+134.3% | Added |
| State Street Corp | 1,303,023 | $49.4M | 0.00% | −140,536−9.7% | Reduced |
| Holocene Advisors, LP | 1,205,377 | $45.7M | 0.11% | +1,205,377 | New |
| Geode Capital Management, LLC | 1,123,411 | $42.6M | 0.00% | +168,851+17.7% | Added |
| Polar Capital Holdings Plc | 1,058,776 | $40.1M | 0.19% | +1,058,776 | New |
| Boothbay Fund Management, LLC | 942,626 | $35.7M | 0.92% | +125,700+15.4% | Added |
| Pictet Asset Management Holding SA | 929,169 | $35.2M | 0.03% | −338,824−26.7% | Reduced |
| Alliancebernstein L.P. | 882,415 | $33.5M | 0.01% | +855,348+3,160.1% | Added |
| American Century Companies Inc | 879,682 | $33.4M | 0.02% | +44,901+5.4% | Added |
| Wellington Management Group LLP | 783,445 | $29.7M | 0.01% | +667,997+578.6% | Added |
| Bank of America Corp | 768,265 | $29.1M | 0.00% | +504,909+191.7% | Added |
| Affinity Asset Advisors, LLC | 750,000 | $28.4M | 2.65% | −150,000−16.7% | Reduced |
| Goldman Sachs Group Inc | 711,661 | $27.0M | 0.00% | +84,874+13.5% | Added |
| Barclays PLC | 653,830 | $24.8M | 0.01% | +509,946+354.4% | Added |
| BNP Paribas Arbitrage, SA | 626,148 | $23.7M | 0.02% | +622,040+15,142.2% | Added |
| D. E. Shaw & Co., Inc. | 610,923 | $23.2M | 0.02% | +36,716+6.4% | Added |
| Candriam Luxembourg S.C.A. | 567,781 | $21.5M | 0.11% | −256,406−31.1% | Reduced |
| Pale Fire Capital SE | 532,407 | $20.2M | 2.21% | +85,781+19.2% | Added |
| Armistice Capital, LLC | 507,650 | $19.3M | 0.60% | +329,650+185.2% | Added |
| Parkman Healthcare Partners LLC | 455,523 | $17.3M | 1.90% | −8,078−1.7% | Reduced |
| Nearwater Capital Markets, Ltd | 450,000 | $17.1M | 0.23% | +450,000 | New |
| Charles Schwab Investment Management Inc | 409,187 | $15.5M | 0.00% | +84,982+26.2% | Added |
| Rock Springs Capital Management LP | 408,313 | $15.5M | 0.91% | +83,800+25.8% | Added |
| Millennium Management LLC | 404,589 | $15.3M | 0.01% | +161,020+66.1% | Added |
| Northern Trust Corp | 390,807 | $14.8M | 0.00% | +51,782+15.3% | Added |
| Jennison Associates LLC | 376,346 | $14.3M | 0.01% | −858,976−69.5% | Reduced |
| 22NW, LP | 358,325 | $13.6M | 7.07% | −201,717−36.0% | Reduced |
| Swedbank AB | 299,300 | $11.3M | 0.01% | −84,500−22.0% | Reduced |
| Findell Capital Management LLC | 250,000 | $9.48M | 4.33% | +250,000 | New |
| Sphera Funds Management Ltd. | 219,910 | $8.34M | 1.98% | −261,064−54.3% | Reduced |
| Simplify Asset Management Inc. | 218,726 | $8.29M | 0.17% | +218,726 | New |
| HighVista Strategies LLC | 209,829 | $7.96M | 1.95% | +59,691+39.8% | Added |
| Tang Capital Management LLC | 200,000 | $7.58M | 0.29% | 00.0% | Unchanged |
| Invesco Ltd. | 187,986 | $7.13M | 0.00% | +162,243+630.2% | Added |
| JPMorgan Chase & Co | 183,680 | $6.97M | 0.00% | +158,180+620.3% | Added |
| Qube Research & Technologies Ltd | 180,426 | $6.84M | 0.01% | −170,687−48.6% | Reduced |
| Velan Capital Investment Management LP | 175,600 | $6.66M | 6.25% | +1,000+0.6% | Added |
| Atika Capital Management LLC | 174,000 | $6.60M | 0.56% | +174,000 | New |
| Moore Capital Management, LP | 165,000 | $6.26M | 0.12% | +165,000 | New |
| Rhenman & Partners Asset Management AB | 165,000 | $6.26M | 0.69% | +165,000 | New |
| Citigroup Inc | 163,168 | $6.19M | 0.00% | +136,050+501.7% | Added |
| Nantahala Capital Management, LLC | 158,713 | $6.02M | 0.37% | −195,269−55.2% | Reduced |
| StemPoint Capital LP | 158,112 | $6.00M | 1.21% | −473,474−75.0% | Reduced |
| Burkehill Global Management, LP | 150,000 | $5.69M | 0.32% | +150,000 | New |
| Dimensional Fund Advisors LP | 146,778 | $5.57M | 0.00% | −40,606−21.7% | Reduced |
| Voya Investment Management LLC | 138,526 | $5.25M | 0.01% | +88,050+174.4% | Added |
| HRT Financial LP | 134,038 | $5.08M | 0.02% | +123,961+1,230.1% | Added |
| EAM Investors, LLC | 127,547 | $4.76M | 0.55% | +127,547 | New |
| Jain Global LLC | 120,854 | $4.58M | 0.06% | +120,854 | New |
| Bank of New York Mellon Corp | 113,797 | $4.32M | 0.00% | +17,382+18.0% | Added |
| Ensign Peak Advisors, Inc | 107,640 | $4.08M | 0.01% | 00.0% | Unchanged |
| Greenland Capital Management LP | 105,853 | $4.01M | 0.59% | +95,853+958.5% | Added |
| Adage Capital Partners GP, L.L.C. | 105,000 | $3.98M | 0.01% | +105,000 | New |
| Blue Owl Capital Holdings LP | 100,944 | $3.83M | 1.19% | −235,000−70.0% | Reduced |
| SG Americas Securities, LLC | 100,037 | $3.79M | 0.01% | −23,950−19.3% | Reduced |
| Zimmer Partners, LP | 100,000 | $3.79M | 0.09% | −62,733−38.5% | Reduced |
| Ameriprise Financial Inc | 97,147 | $3.68M | 0.00% | +46,290+91.0% | Added |
| UBS Group AG | 89,504 | $3.39M | 0.00% | −25,635−22.3% | Reduced |
| Swiss National Bank | 88,500 | $3.36M | 0.00% | +26,600+43.0% | Added |
| Nuveen, LLC | 86,916 | $3.30M | 0.00% | +9,269+11.9% | Added |
| DAFNA Capital Management LLC | 83,490 | $3.17M | 0.78% | −288,033−77.5% | Reduced |
| Silverarc Capital Management, LLC | 80,000 | $3.03M | 0.44% | −35,282−30.6% | Reduced |
| ADAR1 Capital Management, LLC | 78,238 | $2.97M | 0.29% | −223,887−74.1% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 78,092 | $2.96M | 0.05% | −83,042−51.5% | Reduced |
| Hudson Bay Capital Management LP | 75,768 | $2.87M | 0.02% | +75,768 | New |
| Cinctive Capital Management LP | 71,713 | $2.72M | 0.14% | +55,600+345.1% | Added |
| UBS Asset Management Americas Inc | 59,042 | $2.24M | 0.00% | +34,638+141.9% | Added |
| Susquehanna International Group, LLP | 57,223 | $2.17M | 0.00% | +1,137+2.0% | Added |
| Artia Global Partners LP | 56,600 | $2.15M | 0.38% | +15,500+37.7% | Added |
| Rhumbline Advisers | 55,291 | $2.10M | 0.00% | +1,695+3.2% | Added |
| Hennion & Walsh Asset Management, Inc. | 52,848 | $2.00M | 0.07% | +21,753+70.0% | Added |
| Prudential Financial Inc | 50,425 | $1.91M | 0.00% | −301,800−85.7% | Reduced |
| Algert Global LLC | 47,500 | $1.80M | 0.03% | +47,500 | New |
| Renaissance Technologies LLC | 47,400 | $1.80M | 0.00% | −129,526−73.2% | Reduced |
| Erste Asset Management GmbH | 45,000 | $1.77M | 0.02% | 00.0% | Unchanged |
| Legal & General Group Plc | 45,429 | $1.72M | 0.00% | +9,380+26.0% | Added |
| Trexquant Investment LP | 43,973 | $1.67M | 0.02% | −138,692−75.9% | Reduced |
| J. Goldman & Co LP | 43,868 | $1.66M | 0.06% | −13,767−23.9% | Reduced |
| Squarepoint Ops LLC | 43,013 | $1.63M | 0.00% | +31,498+273.5% | Added |
| Capstone Investment Advisors, LLC | 42,276 | $1.60M | 0.01% | +42,276 | New |
| Resolute Capital Asset Partners LLC | 40,000 | $1.52M | 0.79% | +40,000 | New |
| Lion Point Capital, LP | 39,000 | $1.48M | 8.40% | −40,000−50.6% | Reduced |
| Jane Street Group, LLC | 37,145 | $1.41M | 0.00% | +37,145 | New |