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Mineralys Therapeutics, Inc.

MLYS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001933414

In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Mineralys Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
193
+27 vs. Q2 2025
Shares held
79.3M
+13.6M (+20.8%) vs. Q2 2025
Total value
$3.01B
+$2.12B (+238.4%) vs. Q2 2025
New holders
42
69 more added
Sold out
15
63 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 193 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 68 institutionsQ2 2023: 68 institutionsQ3 2023: 77 institutionsQ4 2023: 87 institutionsQ1 2024: 92 institutionsQ2 2024: 94 institutionsQ3 2024: 106 institutionsQ4 2024: 109 institutionsQ1 2025: 149 institutionsQ2 2025: 166 institutionsQ3 2025: 193 institutionsQ4 2025: 223 institutionsQ1 2026: 215 institutionsQ2 2026: 225 institutions
Value heldQ3 2025: $3.01B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $385.4MQ2 2023: $429.2MQ3 2023: $252.1MQ4 2023: $298.5MQ1 2024: $540.6MQ2 2024: $516.6MQ3 2024: $540.1MQ4 2024: $572.2MQ1 2025: $966.2MQ2 2025: $888.8MQ3 2025: $3.01BQ4 2025: $3.21BQ1 2026: $2.46BQ2 2026: $2.69B
Institutions holding MLYS and their total value by quarter
QuarterHoldersValue
Q2 2026225$2.69B
Q1 2026215$2.46B
Q4 2025223$3.21B
Q3 2025193$3.01B
Q2 2025166$888.8M
Q1 2025149$966.2M
Q4 2024109$572.2M
Q3 2024106$540.1M
Q2 202494$516.6M
Q1 202492$540.6M
Q4 202387$298.5M
Q3 202377$252.1M
Q2 202368$429.2M
Q1 202368$385.4M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding MLYS in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
California State Teachers Retirement System36,599$1.39M0.00%+70.0%Added
Y-Intercept (Hong Kong) Ltd36,373$1.38M0.03%+15,093+70.9%Added
Sectoral Asset Management Inc33,885$1.28M0.79%−348,530−91.1%Reduced
Allianz Asset Management GmbH33,700$1.28M0.00%+21,400+174.0%Added
Rafferty Asset Management, LLC31,685$1.20M0.00%−25,690−44.8%Reduced
Deutsche Bank AG30,930$1.17M0.00%−425,984−93.2%Reduced
Wells Fargo & Company30,054$1.14M0.00%−1,703−5.4%Reduced
State of Wisconsin Investment Board26,926$1.02M0.00%+2,375+9.7%Added
Bellevue Group AG26,605$1.01M0.02%+11,049+71.0%Added
MetLife Investment Management22,709$861.1K0.00%−1,305−5.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)22,318$846.3K0.00%−556−2.4%Reduced
Creative Planning22,295$845.4K0.00%−2,566−10.3%Reduced
Price T Rowe Associates Inc21,383$811.0K0.00%+1,815+9.3%Added
Janus Henderson Group PLC19,848$752.5K0.00%+8,248+71.1%Added
Mirae Asset Global ETFs Holdings Ltd.19,716$749.9K0.00%−4,521−18.7%Reduced
Mark Asset Management LP19,465$738.1K0.08%+19,465New
XTX Topco Ltd18,840$714.4K0.04%+18,840New
Quantinno Capital Management LP18,627$706.3K0.00%+5,030+37.0%Added
Verition Fund Management LLC18,463$700.1K0.00%+18,463New
AQR Capital Management LLC18,122$687.2K0.00%−9,779−35.0%Reduced
Mariner, LLC16,409$622.2K0.00%−12,295−42.8%Reduced
Kingswood Wealth Advisors, LLC16,143$612.1K0.04%+16,143New
Balyasny Asset Management LLC15,268$579.0K0.00%−190,455−92.6%Reduced
Manufacturers Life Insurance Company, The14,766$559.9K0.00%−9−0.1%Reduced
Schonfeld Strategic Advisors LLC14,618$554.3K0.00%−238,581−94.2%Reduced
Connor, Clark & Lunn Investment Management Ltd.14,249$540.3K0.00%+14,249New
Caption Management, LLC13,000$493.0K0.03%−20,000−60.6%Reduced
Quest Partners LLC12,605$478.0K0.03%−2,236−15.1%Reduced
New York State Common Retirement Fund12,564$476.4K0.00%+4,800+61.8%Added
Optimize Financial Inc12,207$462.9K0.24%+12,207New
Advisor Group Holdings, Inc.28,524$448.3K0.00%+27,199+2,052.8%Added
China Universal Asset Management Co., Ltd.11,621$440.7K0.04%−1,469−11.2%Reduced
Police & Firemen's Retirement System of New Jersey10,966$415.8K0.00%+1,732+18.8%Added
Change Path, LLC10,750$407.6K0.01%00.0%Unchanged
Arizona State Retirement System10,607$402.2K0.00%+10,607New
SEI Investments Co9,865$374.1K0.00%+9,865New
Teacher Retirement System of Texas9,686$367.3K0.00%+9,686New
Oxford Asset Management LLP9,123$345.9K0.11%+9,123New
ProShare Advisors LLC9,055$343.4K0.00%−1,402−13.4%Reduced
Scientech Research LLC7,964$302.0K0.11%+7,964New
Virtus Investment Advisers, Inc.7,626$289.2K0.08%+1,324+21.0%Added
State Board of Administration of Florida Retirement System7,561$286.7K0.00%+7,561New
Profund Advisors LLC7,256$275.1K0.01%−4,875−40.2%Reduced
KLP Kapitalforvaltning AS6,700$254.1K0.00%00.0%Unchanged
ExodusPoint Capital Management, LP6,670$252.9K0.00%−165,882−96.1%Reduced
Bridgefront Capital, LLC6,338$240.3K0.07%+6,338New
FORA Capital, LLC6,325$239.8K0.04%+6,325New
Victory Capital Management Inc5,707$216.4K0.00%+5,707New
CWM, LLC5,597$212.0K0.00%−654−10.5%Reduced
Letko, Brosseau & Associates Inc5,475$207.6K0.00%−11,025−66.8%Reduced
Simplex Trading, LLC4,423$167.0K0.00%+4,423New
Point72 (DIFC) Ltd4,037$153.1K0.01%+4,037New
Tower Research Capital LLC (TRC)3,371$127.8K0.00%+622+22.6%Added
Ameritas Investment Partners, Inc.3,269$124.0K0.00%−726−18.2%Reduced
Russell Investments Group, Ltd.3,264$123.8K0.00%+3,241+14,091.3%Added
Mirae Asset Global Investments Co., Ltd.2,563$97.2K0.00%+45+1.8%Added
The PNC Financial Services Group, Inc.2,234$84.7K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC2,065$78.3K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,426$54.1K0.00%+152+11.9%Added
SBI Securities Co., Ltd.1,126$42.7K0.00%−598−34.7%Reduced
Smartleaf Asset Management LLC1,017$40.0K0.00%+676+198.2%Added
Amalgamated Bank985$37.0K0.00%00.0%Unchanged
Comerica Bank780$29.6K0.00%−23−2.9%Reduced
Covestor Ltd567$21.0K0.01%−172−23.3%Reduced
Versant Capital Management, Inc513$19.5K0.00%00.0%Unchanged
GAMMA Investing LLC436$16.5K0.00%−1−0.2%Reduced
Royal Bank of Canada422$16.0K0.00%−9,141−95.6%Reduced
Massmutual Trust Co FSB319$12.1K0.00%00.0%Unchanged
Optiver Holding B.V.286$10.8K0.00%+286New
SRS Capital Advisors, Inc.270$10.2K0.00%+270New
Daiwa Securities Group Inc.199$8.00K0.00%−35−15.0%Reduced
US Bancorp204$7.74K0.00%+30+17.2%Added
EverSource Wealth Advisors, LLC152$5.76K0.00%−205−57.4%Reduced
Caitong International Asset Management Co., Ltd108$4.09K0.00%−84−43.8%Reduced
FSA Wealth Management LLC100$3.79K0.00%+100New
Sterling Capital Management LLC95$3.60K0.00%00.0%Unchanged
True Wealth Design, LLC76$2.88K0.00%00.0%Unchanged
Avion Wealth78$2.00K0.00%00.0%Unchanged
Rothschild Investment LLC50$1.90K0.00%−25−33.3%Reduced
Private Wealth Management Group, LLC50$1.90K0.00%00.0%Unchanged
Allworth Financial LP44$1.67K0.00%+10+29.4%Added
Quantbot Technologies LP39$1.48K0.00%+39New
Rise Advisors, LLC37$1.40K0.00%−25−40.3%Reduced
Parkside Financial Bank & Trust35$1.33K0.00%00.0%Unchanged
Farther Finance Advisors, LLC33$1.25K0.00%+16+94.1%Added
Rockefeller Capital Management L.P.31$1.18K0.00%+31New
Larson Financial Group LLC30$1.14K0.00%+24+400.0%Added
Parallel Advisors, LLC22$8340.00%00.0%Unchanged
Federated Hermes, Inc.21$7960.00%−16,507−99.9%Reduced
MAI Capital Management18$6830.00%00.0%Unchanged
Quadrant Capital Group LLC10$3800.00%+10New
IFP Advisors, Inc2$760.00%+2Added
Essential Partners LLC1$380.00%00.0%Unchanged
Dark Forest Capital Management LP0$00.00%−126,726−100.0%Sold out
Woodline Partners LP0$00.00%−87,868−100.0%Sold out
UBS Oconnor LLC0$00.00%−79,723−100.0%Sold out
Walleye Capital LLC0$00.00%−73,921−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−48,401−100.0%Sold out
Man Group plc0$00.00%−21,852−100.0%Sold out
Intech Investment Management LLC0$00.00%−21,629−100.0%Sold out