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Mineralys Therapeutics, Inc.

MLYS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001933414

In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Mineralys Therapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
193
+27 vs. Q2 2025
Shares held
79.3M
+13.6M (+20.8%) vs. Q2 2025
Total value
$3.01B
+$2.12B (+238.4%) vs. Q2 2025
New holders
42
69 more added
Sold out
15
63 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 193 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 68 institutionsQ2 2023: 68 institutionsQ3 2023: 77 institutionsQ4 2023: 87 institutionsQ1 2024: 92 institutionsQ2 2024: 94 institutionsQ3 2024: 106 institutionsQ4 2024: 109 institutionsQ1 2025: 149 institutionsQ2 2025: 166 institutionsQ3 2025: 193 institutionsQ4 2025: 223 institutionsQ1 2026: 215 institutionsQ2 2026: 225 institutions
Value heldQ3 2025: $3.01B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $385.4MQ2 2023: $429.2MQ3 2023: $252.1MQ4 2023: $298.5MQ1 2024: $540.6MQ2 2024: $516.6MQ3 2024: $540.1MQ4 2024: $572.2MQ1 2025: $966.2MQ2 2025: $888.8MQ3 2025: $3.01BQ4 2025: $3.21BQ1 2026: $2.46BQ2 2026: $2.69B
Institutions holding MLYS and their total value by quarter
QuarterHoldersValue
Q2 2026225$2.69B
Q1 2026215$2.46B
Q4 2025223$3.21B
Q3 2025193$3.01B
Q2 2025166$888.8M
Q1 2025149$966.2M
Q4 2024109$572.2M
Q3 2024106$540.1M
Q2 202494$516.6M
Q1 202492$540.6M
Q4 202387$298.5M
Q3 202377$252.1M
Q2 202368$429.2M
Q1 202368$385.4M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q2 2025.

Institutions holding MLYS in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Essential Partners LLC1$380.00%00.0%Unchanged
IFP Advisors, Inc2$760.00%+2Added
Quadrant Capital Group LLC10$3800.00%+10New
MAI Capital Management18$6830.00%00.0%Unchanged
Federated Hermes, Inc.21$7960.00%−16,507−99.9%Reduced
Parallel Advisors, LLC22$8340.00%00.0%Unchanged
Larson Financial Group LLC30$1.14K0.00%+24+400.0%Added
Rockefeller Capital Management L.P.31$1.18K0.00%+31New
Farther Finance Advisors, LLC33$1.25K0.00%+16+94.1%Added
Parkside Financial Bank & Trust35$1.33K0.00%00.0%Unchanged
Rise Advisors, LLC37$1.40K0.00%−25−40.3%Reduced
Quantbot Technologies LP39$1.48K0.00%+39New
Allworth Financial LP44$1.67K0.00%+10+29.4%Added
Rothschild Investment LLC50$1.90K0.00%−25−33.3%Reduced
Private Wealth Management Group, LLC50$1.90K0.00%00.0%Unchanged
Avion Wealth78$2.00K0.00%00.0%Unchanged
True Wealth Design, LLC76$2.88K0.00%00.0%Unchanged
Sterling Capital Management LLC95$3.60K0.00%00.0%Unchanged
FSA Wealth Management LLC100$3.79K0.00%+100New
Caitong International Asset Management Co., Ltd108$4.09K0.00%−84−43.8%Reduced
EverSource Wealth Advisors, LLC152$5.76K0.00%−205−57.4%Reduced
US Bancorp204$7.74K0.00%+30+17.2%Added
Daiwa Securities Group Inc.199$8.00K0.00%−35−15.0%Reduced
SRS Capital Advisors, Inc.270$10.2K0.00%+270New
Optiver Holding B.V.286$10.8K0.00%+286New
Massmutual Trust Co FSB319$12.1K0.00%00.0%Unchanged
Royal Bank of Canada422$16.0K0.00%−9,141−95.6%Reduced
GAMMA Investing LLC436$16.5K0.00%−1−0.2%Reduced
Versant Capital Management, Inc513$19.5K0.00%00.0%Unchanged
Covestor Ltd567$21.0K0.01%−172−23.3%Reduced
Comerica Bank780$29.6K0.00%−23−2.9%Reduced
Amalgamated Bank985$37.0K0.00%00.0%Unchanged
Smartleaf Asset Management LLC1,017$40.0K0.00%+676+198.2%Added
SBI Securities Co., Ltd.1,126$42.7K0.00%−598−34.7%Reduced
GF Fund Management Co. Ltd.1,426$54.1K0.00%+152+11.9%Added
Nisa Investment Advisors, LLC2,065$78.3K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.2,234$84.7K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,563$97.2K0.00%+45+1.8%Added
Russell Investments Group, Ltd.3,264$123.8K0.00%+3,241+14,091.3%Added
Ameritas Investment Partners, Inc.3,269$124.0K0.00%−726−18.2%Reduced
Tower Research Capital LLC (TRC)3,371$127.8K0.00%+622+22.6%Added
Point72 (DIFC) Ltd4,037$153.1K0.01%+4,037New
Simplex Trading, LLC4,423$167.0K0.00%+4,423New
Letko, Brosseau & Associates Inc5,475$207.6K0.00%−11,025−66.8%Reduced
CWM, LLC5,597$212.0K0.00%−654−10.5%Reduced
Victory Capital Management Inc5,707$216.4K0.00%+5,707New
FORA Capital, LLC6,325$239.8K0.04%+6,325New
Bridgefront Capital, LLC6,338$240.3K0.07%+6,338New
ExodusPoint Capital Management, LP6,670$252.9K0.00%−165,882−96.1%Reduced
KLP Kapitalforvaltning AS6,700$254.1K0.00%00.0%Unchanged
Profund Advisors LLC7,256$275.1K0.01%−4,875−40.2%Reduced
State Board of Administration of Florida Retirement System7,561$286.7K0.00%+7,561New
Virtus Investment Advisers, Inc.7,626$289.2K0.08%+1,324+21.0%Added
Scientech Research LLC7,964$302.0K0.11%+7,964New
ProShare Advisors LLC9,055$343.4K0.00%−1,402−13.4%Reduced
Oxford Asset Management LLP9,123$345.9K0.11%+9,123New
Teacher Retirement System of Texas9,686$367.3K0.00%+9,686New
SEI Investments Co9,865$374.1K0.00%+9,865New
Arizona State Retirement System10,607$402.2K0.00%+10,607New
Change Path, LLC10,750$407.6K0.01%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey10,966$415.8K0.00%+1,732+18.8%Added
China Universal Asset Management Co., Ltd.11,621$440.7K0.04%−1,469−11.2%Reduced
Advisor Group Holdings, Inc.28,524$448.3K0.00%+27,199+2,052.8%Added
Optimize Financial Inc12,207$462.9K0.24%+12,207New
New York State Common Retirement Fund12,564$476.4K0.00%+4,800+61.8%Added
Quest Partners LLC12,605$478.0K0.03%−2,236−15.1%Reduced
Caption Management, LLC13,000$493.0K0.03%−20,000−60.6%Reduced
Connor, Clark & Lunn Investment Management Ltd.14,249$540.3K0.00%+14,249New
Schonfeld Strategic Advisors LLC14,618$554.3K0.00%−238,581−94.2%Reduced
Manufacturers Life Insurance Company, The14,766$559.9K0.00%−9−0.1%Reduced
Balyasny Asset Management LLC15,268$579.0K0.00%−190,455−92.6%Reduced
Kingswood Wealth Advisors, LLC16,143$612.1K0.04%+16,143New
Mariner, LLC16,409$622.2K0.00%−12,295−42.8%Reduced
AQR Capital Management LLC18,122$687.2K0.00%−9,779−35.0%Reduced
Verition Fund Management LLC18,463$700.1K0.00%+18,463New
Quantinno Capital Management LP18,627$706.3K0.00%+5,030+37.0%Added
XTX Topco Ltd18,840$714.4K0.04%+18,840New
Mark Asset Management LP19,465$738.1K0.08%+19,465New
Mirae Asset Global ETFs Holdings Ltd.19,716$749.9K0.00%−4,521−18.7%Reduced
Janus Henderson Group PLC19,848$752.5K0.00%+8,248+71.1%Added
Price T Rowe Associates Inc21,383$811.0K0.00%+1,815+9.3%Added
Creative Planning22,295$845.4K0.00%−2,566−10.3%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)22,318$846.3K0.00%−556−2.4%Reduced
MetLife Investment Management22,709$861.1K0.00%−1,305−5.4%Reduced
Bellevue Group AG26,605$1.01M0.02%+11,049+71.0%Added
State of Wisconsin Investment Board26,926$1.02M0.00%+2,375+9.7%Added
Wells Fargo & Company30,054$1.14M0.00%−1,703−5.4%Reduced
Deutsche Bank AG30,930$1.17M0.00%−425,984−93.2%Reduced
Rafferty Asset Management, LLC31,685$1.20M0.00%−25,690−44.8%Reduced
Allianz Asset Management GmbH33,700$1.28M0.00%+21,400+174.0%Added
Sectoral Asset Management Inc33,885$1.28M0.79%−348,530−91.1%Reduced
Y-Intercept (Hong Kong) Ltd36,373$1.38M0.03%+15,093+70.9%Added
California State Teachers Retirement System36,599$1.39M0.00%+70.0%Added
Jane Street Group, LLC37,145$1.41M0.00%+37,145New
Lion Point Capital, LP39,000$1.48M8.40%−40,000−50.6%Reduced
Resolute Capital Asset Partners LLC40,000$1.52M0.79%+40,000New
Capstone Investment Advisors, LLC42,276$1.60M0.01%+42,276New
Squarepoint Ops LLC43,013$1.63M0.00%+31,498+273.5%Added
J. Goldman & Co LP43,868$1.66M0.06%−13,767−23.9%Reduced
Trexquant Investment LP43,973$1.67M0.02%−138,692−75.9%Reduced