Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 12 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Mineralys Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 215
- −5 vs. Q4 2025
- Shares held
- 90.3M
- +5.56M (+6.6%) vs. Q4 2025
- Total value
- $2.46B
- −$621.1M (−20.2%) vs. Q4 2025
- New holders
- 33
- 98 more added
- Sold out
- 38
- 52 more reduced
3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Catalys Pacific, LLC | 7,903,838 | $214.1M | 92.81% | 00.0% | Unchanged |
| Ra Capital Management, L.P. | 7,692,750 | $208.4M | 2.21% | +369,000+5.0% | Added |
| Samsara BioCapital, LLC | 5,871,018 | $159.0M | 15.45% | 00.0% | Unchanged |
| FMR LLC | 4,861,104 | $131.7M | 0.01% | −196,405−3.9% | Reduced |
| BlackRock, Inc. | 4,481,582 | $121.4M | 0.00% | +153,904+3.6% | Added |
| Wellington Management Group LLP | 3,359,068 | $91.0M | 0.02% | +2,574,801+328.3% | Added |
| State Street Corp | 2,935,940 | $79.5M | 0.00% | −249,059−7.8% | Reduced |
| Caligan Partners LP | 2,772,654 | $75.1M | 5.31% | 00.0% | Unchanged |
| Vanguard Capital Management LLC | 2,454,363 | $66.5M | 0.00% | +2,454,363 | New |
| Laurion Capital Management LP | 2,232,040 | $60.5M | 5.67% | +518,555+30.3% | Added |
| OrbiMed Advisors LLC | 2,052,900 | $55.6M | 1.26% | +1,072,500+109.4% | Added |
| Point72 Asset Management, L.P. | 1,911,433 | $51.8M | 0.09% | +704,213+58.3% | Added |
| Franklin Resources Inc | 1,784,662 | $48.3M | 0.01% | −4,085−0.2% | Reduced |
| Andera Partners | 1,591,917 | $43.1M | 24.38% | 00.0% | Unchanged |
| Sr One Capital Management, LP | 1,563,966 | $42.4M | 4.63% | 00.0% | Unchanged |
| Suvretta Capital Management, LLC | 1,538,662 | $41.7M | 1.13% | 00.0% | Unchanged |
| Polar Capital Holdings Plc | 1,500,749 | $40.7M | 0.18% | +99,608+7.1% | Added |
| Price T Rowe Associates Inc | 1,343,313 | $36.4M | 0.00% | +18,193+1.4% | Added |
| Sphera Funds Management Ltd. | 1,339,971 | $36.3M | 6.24% | +890,968+198.4% | Added |
| Alliancebernstein L.P. | 975,961 | $35.4M | 0.01% | +53,445+5.8% | Added |
| Geode Capital Management, LLC | 1,301,135 | $35.3M | 0.00% | +43,553+3.5% | Added |
| Jennison Associates LLC | 1,266,174 | $34.3M | 0.02% | +7,521+0.6% | Added |
| Armistice Capital, LLC | 1,176,000 | $31.9M | 1.05% | +499,965+74.0% | Added |
| Bank of America Corp | 1,100,372 | $29.8M | 0.00% | +113,092+11.5% | Added |
| Pictet Asset Management Holding SA | 1,034,438 | $28.0M | 0.03% | +181,555+21.3% | Added |
| Boothbay Fund Management, LLC | 1,001,728 | $27.1M | 0.64% | +9,646+1.0% | Added |
| Qube Research & Technologies Ltd | 914,728 | $24.8M | 0.04% | +418,179+84.2% | Added |
| Nantahala Capital Management, LLC | 895,481 | $24.3M | 1.51% | +782,196+690.5% | Added |
| D. E. Shaw & Co., Inc. | 887,192 | $24.0M | 0.02% | −263,478−22.9% | Reduced |
| American Century Companies Inc | 884,107 | $24.0M | 0.01% | −23,986−2.6% | Reduced |
| Morgan Stanley | 849,184 | $23.0M | 0.00% | +209,677+32.8% | Added |
| Candriam Luxembourg S.C.A. | 801,904 | $21.7M | 0.11% | +123,517+18.2% | Added |
| Goldman Sachs Group Inc | 785,043 | $21.3M | 0.00% | −665,890−45.9% | Reduced |
| Integral Health Asset Management, LLC | 750,000 | $20.3M | 1.08% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 750,000 | $20.3M | 1.19% | +20,000+2.7% | Added |
| Vanguard Portfolio Management LLC | 706,658 | $19.1M | 0.00% | +706,658 | New |
| Troluce Capital Advisors LLC | 655,000 | $17.7M | 1.88% | +655,000 | New |
| Citadel Advisors LLC | 600,041 | $16.3M | 0.01% | +200,122+50.0% | Added |
| StemPoint Capital LP | 533,378 | $14.4M | 2.78% | +243,329+83.9% | Added |
| Millennium Management LLC | 525,260 | $14.2M | 0.01% | +446,635+568.1% | Added |
| Davern Capital Partners, LP | 447,153 | $12.1M | 3.32% | +236,505+112.3% | Added |
| 22NW, LP | 444,325 | $12.0M | 9.47% | +86,000+24.0% | Added |
| Charles Schwab Investment Management Inc | 443,898 | $12.0M | 0.00% | −17,402−3.8% | Reduced |
| Northern Trust Corp | 442,874 | $12.0M | 0.00% | +143,011+47.7% | Added |
| Rock Springs Capital Management LP | 439,751 | $11.9M | 0.70% | +12,155+2.8% | Added |
| Catalio Capital Management, LP | 439,041 | $11.9M | 2.48% | +107,192+32.3% | Added |
| Capital World Investors | 398,179 | $10.8M | 0.00% | +398,179 | New |
| Renaissance Technologies LLC | 382,800 | $10.4M | 0.02% | +60,700+18.8% | Added |
| Parkman Healthcare Partners LLC | 380,137 | $10.3M | 1.07% | −30,112−7.3% | Reduced |
| Vanguard Fiduciary Trust Co | 375,262 | $10.2M | 0.00% | +375,262 | New |
| Pale Fire Capital SE | 365,626 | $9.90M | 0.87% | +355,272+3,431.3% | Added |
| TimesSquare Capital Management, LLC | 338,798 | $9.18M | 0.16% | −41,302−10.9% | Reduced |
| Two Sigma Investments, LP | 311,488 | $8.44M | 0.01% | −298,915−49.0% | Reduced |
| Lord, Abbett & Co. LLC | 300,913 | $8.15M | 0.03% | −11,483−3.7% | Reduced |
| Rhenman & Partners Asset Management AB | 263,071 | $7.13M | 0.88% | +120,500+84.5% | Added |
| Algert Global LLC | 260,264 | $7.05M | 0.11% | +212,764+447.9% | Added |
| SG Americas Securities, LLC | 225,833 | $6.12M | 0.01% | −4,962−2.1% | Reduced |
| Ameriprise Financial Inc | 221,305 | $6.00M | 0.00% | +175,059+378.5% | Added |
| Voya Investment Management LLC | 216,089 | $5.85M | 0.01% | +103,417+91.8% | Added |
| Russell Investments Group, Ltd. | 203,504 | $5.51M | 0.01% | +28,143+16.0% | Added |
| Findell Capital Management LLC | 202,000 | $5.47M | 1.61% | +152,000+304.0% | Added |
| Schonfeld Strategic Advisors LLC | 177,585 | $4.81M | 0.04% | +127,764+256.4% | Added |
| Buckley Capital Advisors, LLC | 173,100 | $4.69M | 3.97% | −1,200−0.7% | Reduced |
| Tudor Investment Corp Et Al | 155,740 | $4.22M | 0.02% | +116,694+298.9% | Added |
| ADAR1 Capital Management, LLC | 154,686 | $4.19M | 0.25% | +18,455+13.5% | Added |
| Burkehill Global Management, LP | 150,000 | $4.06M | 0.20% | 00.0% | Unchanged |
| AQR Capital Management LLC | 149,086 | $4.04M | 0.00% | +86,786+139.3% | Added |
| Mark Asset Management LP | 144,875 | $3.92M | 0.52% | +144,875 | New |
| PFM Health Sciences, LP | 142,677 | $3.87M | 0.41% | +95,040+199.5% | Added |
| Artia Global Partners LP | 137,800 | $3.73M | 0.84% | 00.0% | Unchanged |
| Dimensional Fund Advisors LP | 137,433 | $3.72M | 0.00% | −203−0.1% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 132,099 | $3.58M | 0.07% | +100,740+321.2% | Added |
| Bank of New York Mellon Corp | 129,964 | $3.52M | 0.00% | −1,875−1.4% | Reduced |
| Swedbank AB | 122,100 | $3.31M | 0.00% | −99,300−44.9% | Reduced |
| Schroder Investment Management Group | 130,592 | $3.07M | 0.00% | 00.0% | Unchanged |
| Ensign Peak Advisors, Inc | 112,190 | $3.04M | 0.01% | 00.0% | Unchanged |
| Nuveen, LLC | 112,007 | $3.03M | 0.00% | −10,940−8.9% | Reduced |
| Squarepoint Ops LLC | 105,491 | $2.86M | 0.01% | −141,313−57.3% | Reduced |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 104,961 | $2.84M | 0.24% | −554,115−84.1% | Reduced |
| Capital Fund Management S.A. | 102,202 | $2.77M | 0.02% | +102,202 | New |
| UBS Group AG | 98,029 | $2.66M | 0.00% | −103,251−51.3% | Reduced |
| HRT Financial LP | 95,920 | $2.60M | 0.01% | +58,684+157.6% | Added |
| Verition Fund Management LLC | 95,122 | $2.58M | 0.02% | +11,282+13.5% | Added |
| Rafferty Asset Management, LLC | 94,358 | $2.56M | 0.01% | −33,559−26.2% | Reduced |
| J. Goldman & Co LP | 94,101 | $2.55M | 0.12% | +46,813+99.0% | Added |
| Brevan Howard Capital Management LP | 90,929 | $2.46M | 0.03% | −48,364−34.7% | Reduced |
| Swiss National Bank | 90,100 | $2.44M | 0.00% | 00.0% | Unchanged |
| CenterBook Partners LP | 89,330 | $2.42M | 0.13% | +63,330+243.6% | Added |
| Ishara Investments LP | 82,000 | $2.22M | 2.24% | +82,000 | New |
| UBS Asset Management Americas Inc | 79,537 | $2.15M | 0.00% | +3,640+4.8% | Added |
| Susquehanna Portfolio Strategies, LLC | 78,092 | $2.12M | 0.03% | 00.0% | Unchanged |
| Hennion & Walsh Asset Management, Inc. | 70,189 | $1.90M | 0.06% | +827+1.2% | Added |
| Seven Fleet Capital Management LP | 69,571 | $1.88M | 0.59% | +27,546+65.5% | Added |
| XTX Topco Ltd | 68,407 | $1.85M | 0.03% | −5,271−7.2% | Reduced |
| Alps Advisors Inc | 64,419 | $1.75M | 0.01% | −568−0.9% | Reduced |
| State of Wisconsin Investment Board | 64,138 | $1.74M | 0.00% | +14,197+28.4% | Added |
| California State Teachers Retirement System | 61,266 | $1.66M | 0.00% | +17,918+41.3% | Added |
| Prudential Financial Inc | 59,555 | $1.61M | 0.00% | −29,510−33.1% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 59,242 | $1.60M | 0.00% | −52,511−47.0% | Reduced |
| Greenland Capital Management LP | 57,500 | $1.56M | 0.31% | −11,500−16.7% | Reduced |