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Mineralys Therapeutics, Inc.

MLYS
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001933414

In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Mineralys Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
215
−5 vs. Q4 2025
Shares held
90.3M
+5.56M (+6.6%) vs. Q4 2025
Total value
$2.46B
−$621.1M (−20.2%) vs. Q4 2025
New holders
33
98 more added
Sold out
38
52 more reduced

3 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 215 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 68 institutionsQ2 2023: 68 institutionsQ3 2023: 77 institutionsQ4 2023: 87 institutionsQ1 2024: 92 institutionsQ2 2024: 94 institutionsQ3 2024: 106 institutionsQ4 2024: 109 institutionsQ1 2025: 149 institutionsQ2 2025: 166 institutionsQ3 2025: 193 institutionsQ4 2025: 223 institutionsQ1 2026: 215 institutionsQ2 2026: 225 institutions
Value heldQ1 2026: $2.46B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $385.4MQ2 2023: $429.2MQ3 2023: $252.1MQ4 2023: $298.5MQ1 2024: $540.6MQ2 2024: $516.6MQ3 2024: $540.1MQ4 2024: $572.2MQ1 2025: $966.2MQ2 2025: $888.8MQ3 2025: $3.01BQ4 2025: $3.21BQ1 2026: $2.46BQ2 2026: $2.69B
Institutions holding MLYS and their total value by quarter
QuarterHoldersValue
Q2 2026225$2.69B
Q1 2026215$2.46B
Q4 2025223$3.21B
Q3 2025193$3.01B
Q2 2025166$888.8M
Q1 2025149$966.2M
Q4 2024109$572.2M
Q3 2024106$540.1M
Q2 202494$516.6M
Q1 202492$540.6M
Q4 202387$298.5M
Q3 202377$252.1M
Q2 202368$429.2M
Q1 202368$385.4M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding MLYS in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Rhumbline Advisers57,444$1.56M0.00%+3,160+5.8%Added
Trexquant Investment LP57,200$1.55M0.01%−55,588−49.3%Reduced
Canada Pension Plan Investment Board51,400$1.39M0.00%+21,800+73.6%Added
Los Angeles Capital Management LLC46,835$1.27M0.00%+46,560+16,930.9%Added
HighVista Strategies LLC46,778$1.27M0.35%−77,766−62.4%Reduced
JPMorgan Chase & Co51,922$1.22M0.00%+5,239+11.2%Added
Invesco Ltd.42,311$1.15M0.00%+13,170+45.2%Added
Profund Advisors LLC41,984$1.14M0.04%−5,040−10.7%Reduced
Deutsche Bank AG40,116$1.09M0.00%+2,871+7.7%Added
Erste Asset Management GmbH45,000$1.06M0.01%00.0%Unchanged
DAFNA Capital Management LLC38,490$1.04M0.24%00.0%Unchanged
Legal & General Group Plc38,473$1.04M0.00%−5,465−12.4%Reduced
Barclays PLC33,877$917.7K0.00%−189,406−84.8%Reduced
Victory Capital Management Inc33,141$897.8K0.00%+260+0.8%Added
Sectoral Asset Management Inc31,618$895.1K0.74%−70.0%Reduced
Vanguard Global Advisers, LLC30,474$825.5K0.00%+30,474New
Bellevue Group AG29,374$795.7K0.02%+9,548+48.2%Added
Vanguard Asset Management, Ltd29,253$792.5K0.00%+29,253New
Mirae Asset Global ETFs Holdings Ltd.29,185$766.7K0.00%+30.0%Added
MetLife Investment Management26,826$726.7K0.00%+821+3.2%Added
Manufacturers Life Insurance Company, The26,411$715.5K0.00%+10,230+63.2%Added
Diadema Partners LP26,347$713.7K0.29%+1,347+5.4%Added
Wells Fargo & Company26,081$706.5K0.00%−30,675−54.0%Reduced
Raymond James Financial Inc24,677$668.5K0.00%−297−1.2%Reduced
Creative Planning24,301$658.3K0.00%+3,198+15.2%Added
Allianz Asset Management GmbH21,900$593.3K0.00%−8,300−27.5%Reduced
Quantinno Capital Management LP20,541$556.5K0.00%+2,298+12.6%Added
Nomura Holdings Inc20,000$541.8K0.00%+20,000New
Janus Henderson Group PLC19,848$537.3K0.00%−1,193,417−98.4%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH19,689$533.4K0.00%+7,692+64.1%Added
Zurcher Kantonalbank (Zurich Cantonalbank)19,641$532.1K0.00%+2,293+13.2%Added
Simplex Trading, LLC19,562$529.9K0.02%+14,760+307.4%Added
Magnetar Financial LLC18,549$502.5K0.01%+18,549New
Eleva Capital SAS17,081$462.7K0.13%+17,081New
BNP Paribas Arbitrage, SA16,716$452.8K0.00%−156,213−90.3%Reduced
Susquehanna International Group, LLP15,770$427.2K0.00%−127,438−89.0%Reduced
State of New Jersey Common Pension Fund D15,604$422.7K0.00%+20+0.1%Added
Persistent Asset Partners Ltd15,401$417.2K0.16%+7,985+107.7%Added
New York State Common Retirement Fund15,364$416.2K0.00%+2,800+22.3%Added
Citigroup Inc15,085$408.7K0.00%−3,230−17.6%Reduced
Handelsbanken Fonder AB14,100$382.0K0.00%00.0%Unchanged
China Universal Asset Management Co., Ltd.14,044$380.5K0.03%+1,148+8.9%Added
Police & Firemen's Retirement System of New Jersey12,683$343.6K0.00%00.0%Unchanged
Arizona State Retirement System12,542$339.8K0.00%−458−3.5%Reduced
MAI Capital Management12,237$331.5K0.00%+12,213+50,887.5%Added
E Fund Management Co., Ltd.11,862$321.3K0.01%+11,862New
SEI Investments Co11,692$316.7K0.00%+2,912+33.2%Added
Intech Investment Management LLC11,259$305.0K0.00%−5,464−32.7%Reduced
Velan Capital Investment Management LP11,000$298.0K0.19%−140,000−92.7%Reduced
Fox Run Management, L.L.C.12,670$297.9K0.05%−1,856−12.8%Reduced
Vanguard Investments Australia, Ltd.10,765$291.6K0.00%+10,765New
Change Path, LLC10,750$291.2K0.01%00.0%Unchanged
Lion Point Capital, LP10,500$284.4K1.70%00.0%Unchanged
ProShare Advisors LLC10,459$283.3K0.00%−1,581−13.1%Reduced
KLP Kapitalforvaltning AS10,400$281.7K0.00%+800+8.3%Added
Entropy Technologies, LP10,180$275.8K0.01%−5,995−37.1%Reduced
Man Group plc10,139$274.7K0.00%+10,139New
Quarry LP10,000$270.9K0.05%+10,000New
VARCOV Co.9,759$264.4K0.10%+9,759New
Virginia Retirement Systems Et Al9,750$264.1K0.00%+400+4.3%Added
Capstone Investment Advisors, LLC9,675$262.1K0.00%+9,675New
Kingswood Wealth Advisors, LLC9,600$260.1K0.01%+2,526+35.7%Added
Marshall Wace, LLP8,987$243.5K0.00%−240,143−96.4%Reduced
Tower Research Capital LLC (TRC)7,923$214.6K0.01%+7,403+1,423.7%Added
State Board of Administration of Florida Retirement System7,672$207.8K0.00%+111+1.5%Added
Virtus Investment Advisers, Inc.7,389$200.2K0.06%+180+2.5%Added
CWM, LLC6,051$163.9K0.00%+953+18.7%Added
Mirae Asset Global Investments Co., Ltd.4,128$111.8K0.00%+282+7.3%Added
Ameritas Investment Partners, Inc.3,798$102.9K0.00%00.0%Unchanged
Nisa Investment Advisors, LLC2,359$63.9K0.00%+410+21.0%Added
The PNC Financial Services Group, Inc.2,234$60.5K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,777$48.1K0.00%+222+14.3%Added
Smartleaf Asset Management LLC1,639$38.5K0.00%+636+63.4%Added
KBC Group NV1,233$33.0K0.00%+1,233New
Advisor Group Holdings, Inc.1,160$31.4K0.00%+5+0.4%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.837$22.7K0.00%+837New
Fifth Third Bancorp784$21.2K0.00%+784New
Rockefeller Capital Management L.P.555$15.0K0.00%+421+314.2%Added
Covestor Ltd567$15.0K0.01%+94+19.9%Added
Versant Capital Management, Inc513$13.9K0.00%00.0%Unchanged
FNY Investment Advisers, LLC500$13.0K0.01%+500New
GAMMA Investing LLC474$12.8K0.00%+23+5.1%Added
Pinnacle Wealth Planning Services, Inc.355$9.62K0.00%00.0%Unchanged
Allworth Financial LP354$9.59K0.00%+135+61.6%Added
Massmutual Trust Co FSB319$8.64K0.00%00.0%Unchanged
Sterling Capital Management LLC306$8.29K0.00%00.0%Unchanged
US Bancorp302$8.18K0.00%+221+272.8%Added
J.Safra Asset Management Corp250$6.77K0.00%+169+208.6%Added
FIL Ltd229$6.20K0.00%+229New
Keating Financial Advisory Services, Inc.226$6.12K0.00%+226New
SMA Capital LLC208$5.63K0.00%+208New
EverSource Wealth Advisors, LLC196$5.31K0.00%+42+27.3%Added
Royal Bank of Canada152$4.00K0.00%−1,377−90.1%Reduced
SBI Securities Co., Ltd.117$3.17K0.00%+1+0.9%Added
Rothschild Investment LLC92$2.49K0.00%+37+67.3%Added
Optiver Holding B.V.80$2.17K0.00%+38+90.5%Added
True Wealth Design, LLC76$2.06K0.00%00.0%Unchanged
Kilter Group LLC69$1.87K0.00%+69New
SRS Capital Advisors, Inc.69$1.87K0.00%−40−36.7%Reduced
Advisory Services Network, LLC41$1.11K0.00%+41New