Mineralys Therapeutics, Inc.
MLYS- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001933414
In the last 90 days, Mineralys Therapeutics, Inc. insiders filed 0 open-market purchases and 10 sales; 225 institutions reported holding it in 13F filings for Q2 2026, worth $2.69B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Mineralys Therapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 223
- +32 vs. Q3 2025
- Shares held
- 88.4M
- +9.06M (+11.4%) vs. Q3 2025
- Total value
- $3.21B
- +$199.8M (+6.6%) vs. Q3 2025
- New holders
- 52
- 82 more added
- Sold out
- 20
- 72 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting MLYS on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 225 | $2.69B |
| Q1 2026 | 215 | $2.46B |
| Q4 2025 | 223 | $3.21B |
| Q3 2025 | 193 | $3.01B |
| Q2 2025 | 166 | $888.8M |
| Q1 2025 | 149 | $966.2M |
| Q4 2024 | 109 | $572.2M |
| Q3 2024 | 106 | $540.1M |
| Q2 2024 | 94 | $516.6M |
| Q1 2024 | 92 | $540.6M |
| Q4 2023 | 87 | $298.5M |
| Q3 2023 | 77 | $252.1M |
| Q2 2023 | 68 | $429.2M |
| Q1 2023 | 68 | $385.4M |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Mineralys Therapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Avion Wealth | 21 | $0 | 0.00% | −57−73.1% | Reduced |
| Essential Partners LLC | 1 | $36 | 0.00% | 00.0% | Unchanged |
| IFP Advisors, Inc | 8 | $290 | 0.00% | +6+300.0% | Added |
| Quadrant Capital Group LLC | 8 | $291 | 0.00% | −2−20.0% | Reduced |
| Clearstead Advisors, LLC | 11 | $400 | 0.00% | +11 | New |
| Parallel Advisors, LLC | 22 | $798 | 0.00% | 00.0% | Unchanged |
| MAI Capital Management | 24 | $871 | 0.00% | +6+33.3% | Added |
| Bessemer Group Inc | 38 | $1.00K | 0.00% | +38 | New |
| Private Wealth Management Group, LLC | 28 | $1.02K | 0.00% | −22−44.0% | Reduced |
| Farther Finance Advisors, LLC | 35 | $1.27K | 0.00% | +2+6.1% | Added |
| Parkside Financial Bank & Trust | 35 | $1.27K | 0.00% | 00.0% | Unchanged |
| Torren Management, LLC | 39 | $1.42K | 0.00% | +39 | New |
| Optiver Holding B.V. | 42 | $1.52K | 0.00% | −244−85.3% | Reduced |
| Rothschild Investment LLC | 55 | $2.00K | 0.00% | +5+10.0% | Added |
| True Wealth Design, LLC | 76 | $2.76K | 0.00% | 00.0% | Unchanged |
| US Bancorp | 81 | $2.94K | 0.00% | −123−60.3% | Reduced |
| J.Safra Asset Management Corp | 81 | $2.94K | 0.00% | +81 | New |
| SRS Capital Advisors, Inc. | 109 | $3.96K | 0.00% | −161−59.6% | Reduced |
| SBI Securities Co., Ltd. | 116 | $4.21K | 0.00% | −1,010−89.7% | Reduced |
| Rockefeller Capital Management L.P. | 134 | $4.86K | 0.00% | +103+332.3% | Added |
| EverSource Wealth Advisors, LLC | 154 | $5.59K | 0.00% | +2+1.3% | Added |
| Larson Financial Group LLC | 154 | $5.59K | 0.00% | +124+413.3% | Added |
| Allworth Financial LP | 219 | $7.95K | 0.00% | +175+397.7% | Added |
| Daiwa Securities Group Inc. | 235 | $9.00K | 0.00% | +36+18.1% | Added |
| Sterling Capital Management LLC | 306 | $11.1K | 0.00% | +211+222.1% | Added |
| Los Angeles Capital Management LLC | 275 | $11.3K | 0.00% | +275 | New |
| Massmutual Trust Co FSB | 319 | $11.6K | 0.00% | 00.0% | Unchanged |
| Pinnacle Wealth Planning Services, Inc. | 355 | $12.9K | 0.00% | +355 | New |
| GAMMA Investing LLC | 451 | $16.4K | 0.00% | +15+3.4% | Added |
| Covestor Ltd | 473 | $17.0K | 0.01% | −94−16.6% | Reduced |
| Versant Capital Management, Inc | 513 | $18.6K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 520 | $18.9K | 0.00% | −2,851−84.6% | Reduced |
| Comerica Bank | 781 | $28.3K | 0.00% | +1+0.1% | Added |
| Navalign, LLC | 900 | $32.7K | 0.01% | +900 | New |
| Smartleaf Asset Management LLC | 1,003 | $35.6K | 0.00% | −14−1.4% | Reduced |
| Advisor Group Holdings, Inc. | 1,155 | $41.9K | 0.00% | −27,369−96.0% | Reduced |
| Amalgamated Bank | 1,470 | $53.0K | 0.00% | +485+49.2% | Added |
| Royal Bank of Canada | 1,529 | $56.0K | 0.00% | +1,107+262.3% | Added |
| GF Fund Management Co. Ltd. | 1,555 | $56.4K | 0.00% | +129+9.0% | Added |
| Nisa Investment Advisors, LLC | 1,949 | $70.7K | 0.00% | −116−5.6% | Reduced |
| The PNC Financial Services Group, Inc. | 2,234 | $81.1K | 0.00% | 00.0% | Unchanged |
| Acadian Asset Management LLC | 2,908 | $104.0K | 0.00% | +2,908 | New |
| Ameritas Investment Partners, Inc. | 3,798 | $137.8K | 0.00% | +529+16.2% | Added |
| Caitong International Asset Management Co., Ltd | 3,823 | $138.7K | 0.03% | +3,715+3,439.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 3,846 | $139.6K | 0.00% | +1,283+50.1% | Added |
| Simplex Trading, LLC | 4,802 | $174.3K | 0.00% | +379+8.6% | Added |
| CWM, LLC | 5,098 | $185.0K | 0.00% | −499−8.9% | Reduced |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 6,384 | $231.7K | 0.03% | +6,384 | New |
| NEOS Investment Management LLC | 6,463 | $234.5K | 0.00% | +6,463 | New |
| Tema ETFs LLC | 6,463 | $234.5K | 0.02% | +6,463 | New |
| Teacher Retirement System of Texas | 6,781 | $246.1K | 0.00% | −2,905−30.0% | Reduced |
| Connor, Clark & Lunn Investment Management Ltd. | 6,860 | $248.9K | 0.00% | −7,389−51.9% | Reduced |
| Cinctive Capital Management LP | 7,037 | $255.4K | 0.01% | −64,676−90.2% | Reduced |
| Kingswood Wealth Advisors, LLC | 7,074 | $256.7K | 0.01% | −9,069−56.2% | Reduced |
| Virtus Investment Advisers, Inc. | 7,209 | $261.6K | 0.07% | −417−5.5% | Reduced |
| Persistent Asset Partners Ltd | 7,416 | $269.1K | 0.13% | +7,416 | New |
| Banque Pictet & Cie SA | 7,486 | $271.7K | 0.00% | +7,486 | New |
| State Board of Administration of Florida Retirement System | 7,561 | $274.4K | 0.00% | 00.0% | Unchanged |
| SEI Investments Co | 8,780 | $318.6K | 0.00% | −1,085−11.0% | Reduced |
| Virginia Retirement Systems Et Al | 9,350 | $339.3K | 0.00% | +9,350 | New |
| KLP Kapitalforvaltning AS | 9,600 | $348.4K | 0.00% | +2,900+43.3% | Added |
| Mariner, LLC | 10,230 | $371.5K | 0.00% | −6,179−37.7% | Reduced |
| Pale Fire Capital SE | 10,354 | $375.7K | 0.05% | −522,053−98.1% | Reduced |
| Lion Point Capital, LP | 10,500 | $381.0K | 1.97% | −28,500−73.1% | Reduced |
| Change Path, LLC | 10,750 | $390.1K | 0.01% | 00.0% | Unchanged |
| FORA Capital, LLC | 11,050 | $401.0K | 0.05% | +4,725+74.7% | Added |
| Quest Partners LLC | 11,328 | $411.1K | 0.02% | −1,277−10.1% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 11,997 | $435.4K | 0.00% | +11,997 | New |
| ProShare Advisors LLC | 12,040 | $436.9K | 0.00% | +2,985+33.0% | Added |
| Optimize Financial Inc | 12,383 | $449.4K | 0.23% | +176+1.4% | Added |
| New York State Common Retirement Fund | 12,564 | $455.9K | 0.00% | 00.0% | Unchanged |
| Police & Firemen's Retirement System of New Jersey | 12,683 | $460.3K | 0.00% | +1,717+15.7% | Added |
| China Universal Asset Management Co., Ltd. | 12,896 | $468.0K | 0.04% | +1,275+11.0% | Added |
| Arizona State Retirement System | 13,000 | $471.8K | 0.00% | +2,393+22.6% | Added |
| Handelsbanken Fonder AB | 14,100 | $512.0K | 0.00% | +14,100 | New |
| Campbell & CO Investment Adviser LLC | 14,404 | $522.7K | 0.03% | +14,404 | New |
| Fox Run Management, L.L.C. | 14,526 | $527.1K | 0.08% | +14,526 | New |
| PSP Research LLC | 14,818 | $537.7K | 0.47% | +14,818 | New |
| State of New Jersey Common Pension Fund D | 15,584 | $565.5K | 0.00% | +15,584 | New |
| Entropy Technologies, LP | 16,175 | $587.0K | 0.03% | +16,175 | New |
| Manufacturers Life Insurance Company, The | 16,181 | $587.2K | 0.00% | +1,415+9.6% | Added |
| Intech Investment Management LLC | 16,723 | $606.9K | 0.01% | +16,723 | New |
| Twin Securities, Inc. | 16,737 | $607.4K | 0.23% | +16,737 | New |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 17,348 | $629.6K | 0.00% | −4,970−22.3% | Reduced |
| Quantinno Capital Management LP | 18,243 | $662.0K | 0.00% | −384−2.1% | Reduced |
| Citigroup Inc | 18,315 | $664.7K | 0.00% | −144,853−88.8% | Reduced |
| Bellevue Group AG | 19,826 | $719.5K | 0.01% | −6,779−25.5% | Reduced |
| Maven Securities LTD | 20,000 | $725.8K | 0.09% | +20,000 | New |
| Creative Planning | 21,103 | $765.8K | 0.00% | −1,192−5.3% | Reduced |
| Atom Investors LP | 22,330 | $810.4K | 0.06% | +22,330 | New |
| Sigma Planning Corp | 24,000 | $871.0K | 0.02% | +24,000 | New |
| Raymond James Financial Inc | 24,974 | $906.3K | 0.00% | +24,974 | New |
| Diadema Partners LP | 25,000 | $907.3K | 0.54% | +25,000 | New |
| CenterBook Partners LP | 26,000 | $943.5K | 0.05% | +26,000 | New |
| MetLife Investment Management | 26,005 | $943.7K | 0.00% | +3,296+14.5% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 29,182 | $1.05M | 0.00% | +9,466+48.0% | Added |
| Invesco Ltd. | 29,141 | $1.06M | 0.00% | −158,845−84.5% | Reduced |
| Canada Pension Plan Investment Board | 29,600 | $1.07M | 0.00% | +29,600 | New |
| Allianz Asset Management GmbH | 30,200 | $1.10M | 0.00% | −3,500−10.4% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 31,359 | $1.14M | 0.03% | −5,014−13.8% | Reduced |