Milestone Pharmaceuticals Inc.

MIST

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001408443

SEC filings (opens in a new tab)

No open-market purchases or sales by Milestone Pharmaceuticals Inc. insiders were filed in the last 90 days; 78 institutions reported holding it in 13F filings for Q2 2026, worth $66.4M in total; no superinvestor holds it.

Q4 2025 vs. Q3 2025

How the institutions holding Milestone Pharmaceuticals Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025 All holders in Q3 2025

13F holders of MIST: Q3 2025 compared with Q4 2025
Measure	Q3 2025	Of which not filed for Q4 2025	Q4 2025	Change
Holders	61	1	80	+20
Shares	34.1M	231.7K	35.0M	+1.09M (+3.2%)
Value	$68.3M	$463.3K	$70.7M	+$2.92M (+4.3%)

1 institution that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (29)

Institutions that held Milestone Pharmaceuticals Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to MIST in Q4 2025
Institution	Shares	Value	% of portfolio
Pavaki Capital Management LLC	8,498,915	$17.2M	11.99%
Stonepine Capital Management, LLC	662,666	$1.34M	1.06%
Point72 Asset Management, L.P.	482,355	$974.4K	0.00%
Squarepoint Ops LLC	249,344	$503.7K	0.00%
Nomura Holdings Inc	225,000	$454.5K	0.00%
BNP Paribas Arbitrage, SA	221,951	$448.3K	0.00%
Acadian Asset Management LLC	176,200	$353.0K	0.00%
Graham Capital Management, L.P.	133,620	$269.9K	0.01%
ADAR1 Capital Management, LLC	100,100	$202.2K	0.02%
Tru Independence Asset Management 2, LLC	100,000	$202.0K	0.13%
SG Americas Securities, LLC	97,375	$197.0K	0.00%
Engineers Gate Manager LP	59,053	$119.3K	0.00%
October Effect Ltd	52,100	$105.2K	0.12%
Qube Research & Technologies Ltd	34,596	$69.9K	0.00%
Scientech Research LLC	30,124	$60.9K	0.04%
Invesco Ltd.	21,893	$44.2K	0.00%
Cetera Investment Advisers	20,722	$41.9K	0.00%
Quantbot Technologies LP	18,990	$38.4K	0.00%
Bayesian Capital Management, LP	17,215	$34.8K	0.08%
SJS Investment Consulting Inc.	15,000	$30.3K	0.00%
Eaton Financial Holdings Company, LLC	12,750	$25.8K	0.01%
Strategic Family Wealth Counselors, L.L.C.	12,675	$25.5K	0.01%
Bronte Capital Management Pty Ltd.	10,414	$21.0K	0.00%
Integral Investment Advisors, Inc.	10,000	$20.2K	0.01%
Tower Research Capital LLC (TRC)	8,980	$18.1K	0.00%
Rockefeller Capital Management L.P.	1,700	$3.43K	0.00%
Medallion Wealth Advisors, LLC	340	$687	0.00%
Rialto Wealth Management, LLC	300	$606	0.00%
Key Capital Management, INC	212	$428	0.00%

Sold out (9)

Institutions that held Milestone Pharmaceuticals Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of MIST in Q4 2025
Institution	Shares, Q3 2025	Value, Q3 2025
OrbiMed Advisors LLC	3,221,828	$6.44M
Sphera Funds Management Ltd.	820,000	$1.64M
Affinity Asset Advisors, LLC	666,666	$1.33M
Goldman Sachs Group Inc	356,567	$713.1K
Quadrature Capital Ltd	223,470	$448.1K
HRT Financial LP	138,812	$277.0K
Simplex Trading, LLC	66,920	$133.0K
Sapient Capital LLC	12,200	$24.8K
Wealthspire Advisors, LLC	1,129	$2.26K

Not filed for Q4 2025 yet (1)

Institutions that held Milestone Pharmaceuticals Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding MIST in Q3 2025 that haven't filed for Q4 2025
Institution	Shares, Q3 2025	Value, Q3 2025
AMH Equity Ltd	231,671	$463.3K