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Lexicon Pharmaceuticals, Inc.

LXRX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001062822

No open-market purchases or sales by Lexicon Pharmaceuticals, Inc. insiders were filed in the last 90 days; 149 institutions reported holding it in 13F filings for Q2 2026, worth $875.1M in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Lexicon Pharmaceuticals, Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025All holders in Q2 2025

13F holders of LXRX: Q2 2025 compared with Q3 2025
MeasureQ2 2025Of which not filed for Q3 2025Q3 2025Change
Holders1231124+2
Shares256.3M11.7K255.1M−1.13M (−0.4%)
Value$242.9M$11.1K$344.4M+$101.5M (+41.8%)

1 institution that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (19)

Institutions that held Lexicon Pharmaceuticals, Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to LXRX in Q3 2025
InstitutionSharesValue% of portfolio
Citadel Advisors LLC2,634,027$3.56M0.00%
Jacobs Levy Equity Management, Inc692,727$935.2K0.00%
Renaissance Technologies LLC292,400$394.7K0.00%
Quadrature Capital Ltd228,209$309.2K0.00%
Jefferies Financial Group Inc.97,400$131.5K0.00%
Headlands Technologies LLC49,647$67.0K0.01%
Acadian Asset Management LLC36,905$49.0K0.00%
Prudential Financial Inc35,000$47.2K0.00%
Wolverine Trading, LLC21,191$29.5K0.00%
Cetera Investment Advisers17,524$23.7K0.00%
State of Wyoming8,526$11.5K0.00%
GF Fund Management Co. Ltd.7,818$10.6K0.00%
SRS Capital Advisors, Inc.5,097$6.88K0.00%
Advisory Services Network, LLC3,242$4.38K0.00%
Caitong International Asset Management Co., Ltd959$1.29K0.00%
Federation des caisses Desjardins du Quebec571$7710.00%
TFC Financial Management500$6750.00%
Rockefeller Capital Management L.P.335$4520.00%
Rhumbline Advisers0$20.00%

Sold out (17)

Institutions that held Lexicon Pharmaceuticals, Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Not filed for Q3 2025 yet (1)

Institutions that held Lexicon Pharmaceuticals, Inc. at the end of Q2 2025 and haven't filed a 13F for Q3 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding LXRX in Q2 2025 that haven't filed for Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
Avantax Advisory Services, Inc.11,724$11.1K