Lexeo Therapeutics, Inc.
LXEO- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001907108
In the last 90 days, Lexeo Therapeutics, Inc. insiders filed 0 open-market purchases and 3 sales; 141 institutions reported holding it in 13F filings for Q2 2026, worth $410.9M in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Lexeo Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 139
- −6 vs. Q4 2025
- Shares held
- 79.9M
- +7.32M (+10.1%) vs. Q4 2025
- Total value
- $458.7M
- −$261.8M (−36.3%) vs. Q4 2025
- New holders
- 21
- 58 more added
- Sold out
- 27
- 38 more reduced
1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting LXEO on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 141 | $410.9M |
| Q1 2026 | 139 | $458.7M |
| Q4 2025 | 146 | $759.2M |
| Q3 2025 | 109 | $327.5M |
| Q2 2025 | 90 | $169.9M |
| Q1 2025 | 88 | $100.0M |
| Q4 2024 | 90 | $194.2M |
| Q3 2024 | 69 | $268.8M |
| Q2 2024 | 60 | $426.3M |
| Q1 2024 | 54 | $361.5M |
| Q4 2023 | 31 | $217.1M |
| Q3 2023 | 0 | $0 |
| Q2 2023 | 0 | $0 |
| Q1 2023 | 0 | $0 |
| Q4 2022 | 0 | $0 |
| Q3 2022 | 0 | $0 |
| Q2 2022 | 0 | $0 |
| Q1 2022 | 0 | $0 |
| Q4 2021 | 0 | $0 |
| Q3 2021 | 0 | $0 |
| Q2 2021 | 0 | $0 |
| Q1 2021 | 0 | $0 |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Lexeo Therapeutics, Inc.; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BNP Paribas Arbitrage, SA | 228,201 | $1.31M | 0.00% | −29,216−11.3% | Reduced |
| Standard Life Aberdeen plc | 245,904 | $1.41M | 0.00% | +245,904 | New |
| Squarepoint Ops LLC | 319,090 | $1.83M | 0.00% | +226,482+244.6% | Added |
| UBS Group AG | 321,737 | $1.85M | 0.00% | +40,654+14.5% | Added |
| AQR Capital Management LLC | 339,623 | $1.95M | 0.00% | +2,237+0.7% | Added |
| DAFNA Capital Management LLC | 377,059 | $2.16M | 0.49% | +36,200+10.6% | Added |
| Vanguard Fiduciary Trust Co | 384,734 | $2.21M | 0.00% | +384,734 | New |
| Morgan Stanley | 402,924 | $2.31M | 0.00% | +262,743+187.4% | Added |
| Qube Research & Technologies Ltd | 465,515 | $2.67M | 0.00% | +332,258+249.3% | Added |
| Bank of America Corp | 491,532 | $2.82M | 0.00% | +331,244+206.7% | Added |
| Northern Trust Corp | 493,666 | $2.83M | 0.00% | +36,614+8.0% | Added |
| Ikarian Capital, LLC | 513,011 | $2.94M | 0.42% | 00.0% | Unchanged |
| Vanguard Portfolio Management LLC | 577,192 | $3.31M | 0.00% | +577,192 | New |
| Blackstone Group Inc. | 904,959 | $5.19M | 0.02% | 00.0% | Unchanged |
| Spruce Street Capital LP | 928,593 | $5.33M | 1.28% | +753,593+430.6% | Added |
| Octagon Capital Advisors LP | 1,100,000 | $6.31M | 0.70% | −625,000−36.2% | Reduced |
| Dimensional Fund Advisors LP | 1,103,584 | $6.33M | 0.00% | +240,692+27.9% | Added |
| 683 Capital Management, LLC | 1,200,000 | $6.89M | 0.64% | +80,000+7.1% | Added |
| Nantahala Capital Management, LLC | 1,200,000 | $6.89M | 0.43% | +200,000+20.0% | Added |
| Suvretta Capital Management, LLC | 1,250,000 | $7.17M | 0.19% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 1,467,350 | $8.42M | 0.51% | +74,189+5.3% | Added |
| Geode Capital Management, LLC | 1,513,777 | $8.69M | 0.00% | +67,890+4.7% | Added |
| Balyasny Asset Management LLC | 1,589,585 | $9.12M | 0.02% | −45,441−2.8% | Reduced |
| Millennium Management LLC | 1,612,780 | $9.26M | 0.01% | +704,756+77.6% | Added |
| Point72 Asset Management, L.P. | 1,680,449 | $9.65M | 0.02% | −214,273−11.3% | Reduced |
| Avoro Capital Advisors LLC | 1,875,000 | $10.8M | 0.11% | −1,425,000−43.2% | Reduced |
| Goldman Sachs Group Inc | 1,949,885 | $11.2M | 0.00% | +1,168,030+149.4% | Added |
| Woodline Partners LP | 2,750,532 | $15.8M | 0.06% | −447,228−14.0% | Reduced |
| Vanguard Capital Management LLC | 3,007,093 | $17.3M | 0.00% | +3,007,093 | New |
| State Street Corp | 3,568,242 | $20.5M | 0.00% | +380,520+11.9% | Added |
| OrbiMed Advisors LLC | 3,602,450 | $20.7M | 0.47% | +1,477,450+69.5% | Added |
| Citadel Advisors LLC | 3,834,999 | $22.0M | 0.02% | +60,682+1.6% | Added |
| Frazier Life Sciences Management, L.P. | 4,424,725 | $25.4M | 0.65% | 00.0% | Unchanged |
| Vestal Point Capital, LP | 4,475,000 | $25.7M | 0.72% | 00.0% | Unchanged |
| Janus Henderson Group PLC | 4,976,429 | $28.5M | 0.01% | −533,206−9.7% | Reduced |
| Ra Capital Management, L.P. | 5,000,000 | $28.7M | 0.30% | 00.0% | Unchanged |
| Affinity Asset Advisors, LLC | 5,050,211 | $29.0M | 1.70% | +1,850,211+57.8% | Added |
| BlackRock, Inc. | 5,110,871 | $29.3M | 0.00% | +203,308+4.1% | Added |
| Paradigm Biocapital Advisors LP | 6,184,134 | $35.5M | 0.73% | +1,420,936+29.8% | Added |
| Siren, L.L.C. | 0 | $0 | 0.00% | −720,622−100.0% | Sold out |
| Silverarc Capital Management, LLC | 0 | $0 | 0.00% | −617,608−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −428,458−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −243,294−100.0% | Sold out |
| Renaissance Technologies LLC | 0 | $0 | 0.00% | −217,772−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −140,096−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −139,835−100.0% | Sold out |
| Two Sigma Advisers, LP | 0 | $0 | 0.00% | −81,300−100.0% | Sold out |
| Atom Investors LP | 0 | $0 | 0.00% | −68,491−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −50,909−100.0% | Sold out |
| American Century Companies Inc | 0 | $0 | 0.00% | −45,988−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −32,898−100.0% | Sold out |
| Winton Group Ltd | 0 | $0 | 0.00% | −26,900−100.0% | Sold out |
| Ieq Capital, LLC | 0 | $0 | 0.00% | −24,692−100.0% | Sold out |
| Pale Fire Capital SE | 0 | $0 | 0.00% | −22,302−100.0% | Sold out |
| Omers Administration Corp | 0 | $0 | 0.00% | −20,900−100.0% | Sold out |
| SG Americas Securities, LLC | 0 | $0 | 0.00% | −18,640−100.0% | Sold out |
| Persistent Asset Partners Ltd | 0 | $0 | 0.00% | −16,025−100.0% | Sold out |
| Quest Partners LLC | 0 | $0 | 0.00% | −11,726−100.0% | Sold out |
| Bessemer Group Inc | 0 | $0 | 0.00% | −2,380−100.0% | Sold out |
| Amalgamated Bank | 0 | $0 | 0.00% | −1,982−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −1,085−100.0% | Sold out |
| Daiwa Securities Group Inc. | 0 | $0 | 0.00% | −243−100.0% | Sold out |
| Farther Finance Advisors, LLC | 0 | $0 | 0.00% | −57−100.0% | Sold out |
| Rialto Wealth Management, LLC | 0 | $0 | 0.00% | −53−100.0% | Sold out |
| Clearstead Advisors, LLC | 0 | $0 | 0.00% | −4−100.0% | Sold out |
| Rothschild Investment LLC | 0 | $0 | 0.00% | −1−100.0% | Sold out |
| Vanguard Group Inc | – | – | – | – | Not filed |