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Karyopharm Therapeutics Inc.

KPTI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001503802

In the last 90 days, Karyopharm Therapeutics Inc. insiders filed 0 open-market purchases and 3 sales; 96 institutions reported holding it in 13F filings for Q2 2026, worth $206.8M in total; no superinvestor holds it.

Q3 2025 vs. Q2 2025

How the institutions holding Karyopharm Therapeutics Inc. changed between Q2 2025 and Q3 2025.

All holders in Q3 2025All holders in Q2 2025

13F holders of KPTI: Q2 2025 compared with Q3 2025
MeasureQ2 2025Q3 2025Change
Holders5052+2
Shares4.41M2.98M−1.44M (−32.6%)
Value$19.0M$19.5M+$444.0K (+2.3%)

New holders (7)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q3 2025 but not at the end of Q2 2025.

Institutions new to KPTI in Q3 2025
InstitutionSharesValue% of portfolio
Susquehanna International Group, LLP35,339$231.1K0.00%
ADAR1 Capital Management, LLC25,000$163.5K0.02%
Belvedere Trading LLC14,563$95.2K0.01%
Quent Capital, LLC231$1.51K0.00%
Rise Advisors, LLC131$8570.00%
Advisory Services Network, LLC12$780.00%
Pittenger & Anderson Inc3$200.00%

Sold out (5)

Institutions that held Karyopharm Therapeutics Inc. at the end of Q2 2025 and filed for Q3 2025 without it.

Institutions that sold out of KPTI in Q3 2025
InstitutionShares, Q2 2025Value, Q2 2025
Eversept Partners, LP257,154$1.11M
Citadel Advisors LLC206,781$891.2K
Palo Alto Investors LP187,911$809.9K
Millennium Management LLC31,847$137.3K
Raymond James Financial Inc90$388