Disc Medicine, Inc.
IRON- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001816736
In the last 90 days, Disc Medicine, Inc. insiders filed 0 open-market purchases and 9 sales; 216 institutions reported holding it in 13F filings for Q2 2026, worth $3.13B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Disc Medicine, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 197
- +31 vs. Q3 2025
- Shares held
- 38.3M
- +4.08M (+11.9%) vs. Q3 2025
- Total value
- $3.04B
- +$779.8M (+34.5%) vs. Q3 2025
- New holders
- 42
- 86 more added
- Sold out
- 11
- 48 more reduced
2 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IRON on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 216 | $3.13B |
| Q1 2026 | 203 | $2.67B |
| Q4 2025 | 197 | $3.04B |
| Q3 2025 | 168 | $2.26B |
| Q2 2025 | 152 | $1.80B |
| Q1 2025 | 157 | $1.65B |
| Q4 2024 | 152 | $1.68B |
| Q3 2024 | 132 | $1.35B |
| Q2 2024 | 121 | $1.24B |
| Q1 2024 | 130 | $1.38B |
| Q4 2023 | 112 | $1.17B |
| Q3 2023 | 91 | $934.0M |
| Q2 2023 | 90 | $848.7M |
| Q1 2023 | 45 | $309.6M |
| Q4 2022 | 35 | $215.8M |
| Q3 2022 | 44 | $43.9M |
| Q2 2022 | 51 | $43.8M |
| Q1 2022 | 57 | $39.6M |
| Q4 2021 | 62 | $93.8M |
| Q3 2021 | 62 | $103.5M |
| Q2 2021 | 55 | $165.3M |
| Q1 2021 | 49 | $346.6M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Disc Medicine, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Legal & General Group Plc | 23,653 | $1.88M | 0.00% | −1,494−5.9% | Reduced |
| Russell Investments Group, Ltd. | 23,683 | $1.88M | 0.00% | +21,245+871.4% | Added |
| Alliancebernstein L.P. | 24,540 | $1.95M | 0.00% | 00.0% | Unchanged |
| Bank of Montreal | 24,826 | $1.97M | 0.00% | +7,041+39.6% | Added |
| The PNC Financial Services Group, Inc. | 25,200 | $2.00M | 0.00% | +54+0.2% | Added |
| Eagle Health Investments LP | 27,100 | $2.15M | 0.47% | +27,100 | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 27,301 | $2.17M | 0.00% | +15,863+138.7% | Added |
| Zimmer Partners, LP | 27,500 | $2.18M | 0.06% | −62,663−69.5% | Reduced |
| Rhumbline Advisers | 29,833 | $2.37M | 0.00% | −4,657−13.5% | Reduced |
| RTW Investments, LP | 30,000 | $2.38M | 0.02% | +30,000 | New |
| American Century Companies Inc | 30,328 | $2.41M | 0.00% | +2,390+8.6% | Added |
| Alps Advisors Inc | 31,002 | $2.46M | 0.01% | +14,210+84.6% | Added |
| Wells Fargo & Company | 33,265 | $2.64M | 0.00% | +6,210+23.0% | Added |
| Seven Grand Managers, LLC | 35,000 | $2.78M | 0.21% | +35,000 | New |
| Rafferty Asset Management, LLC | 36,093 | $2.87M | 0.01% | −1,209−3.2% | Reduced |
| Citigroup Inc | 36,176 | $2.87M | 0.00% | +32,131+794.3% | Added |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 40,203 | $3.19M | 0.00% | +39,990+18,774.6% | Added |
| NEXTBio Capital Management LP | 42,778 | $3.40M | 1.99% | +42,778 | New |
| Exome Asset Management LLC | 46,743 | $3.71M | 1.83% | −14,613−23.8% | Reduced |
| HealthInvest Partners AB | 47,967 | $3.81M | 1.22% | +2,277+5.0% | Added |
| Swiss National Bank | 48,000 | $3.81M | 0.00% | +4,400+10.1% | Added |
| Nicholas Investment Partners, LP | 48,082 | $3.82M | 0.28% | −39,921−45.4% | Reduced |
| Nuveen, LLC | 48,471 | $3.85M | 0.00% | +777+1.6% | Added |
| Schroder Investment Management Group | 50,103 | $3.85M | 0.00% | −17,093−25.4% | Reduced |
| Brevan Howard Capital Management LP | 49,713 | $3.89M | 0.07% | +49,713 | New |
| Alyeska Investment Group, L.P. | 50,000 | $3.97M | 0.01% | +50,000 | New |
| Burkehill Global Management, LP | 50,000 | $3.97M | 0.26% | +50,000 | New |
| Manufacturers Life Insurance Company, The | 52,510 | $4.07M | 0.00% | +4,933+10.4% | Added |
| Sio Capital Management, LLC | 57,586 | $4.57M | 0.76% | −227,201−79.8% | Reduced |
| Lazard Asset Management LLC | 58,053 | $4.61M | 0.01% | +58,053 | New |
| ExodusPoint Capital Management, LP | 58,211 | $4.62M | 0.05% | +58,211 | New |
| KVP Capital Advisors, LP | 58,250 | $4.63M | 4.78% | +58,250 | New |
| Invesco Ltd. | 61,070 | $4.85M | 0.00% | +39,627+184.8% | Added |
| Renaissance Technologies LLC | 62,820 | $4.99M | 0.01% | +56,020+823.8% | Added |
| Verition Fund Management LLC | 63,535 | $5.05M | 0.03% | +57,402+936.0% | Added |
| Tudor Investment Corp Et Al | 66,125 | $5.25M | 0.03% | +66,125 | New |
| iA Global Asset Management Inc. | 66,430 | $5.28M | 0.07% | +918+1.4% | Added |
| Bank of New York Mellon Corp | 67,707 | $5.38M | 0.00% | +2,907+4.5% | Added |
| TD Asset Management Inc | 69,634 | $5.53M | 0.00% | +10,386+17.5% | Added |
| Patient Square Capital LP | 74,000 | $5.88M | 1.26% | 00.0% | Unchanged |
| Morgan Stanley | 74,826 | $5.94M | 0.00% | +18,751+33.4% | Added |
| Victory Capital Management Inc | 76,338 | $6.06M | 0.00% | −73,526−49.1% | Reduced |
| Raymond James Financial Inc | 80,274 | $6.18M | 0.00% | −61,205−43.3% | Reduced |
| Ameriprise Financial Inc | 82,984 | $6.59M | 0.00% | +8,634+11.6% | Added |
| DnB Asset Management AS | 84,255 | $6.69M | 0.02% | +78,733+1,425.8% | Added |
| Barclays PLC | 99,612 | $7.91M | 0.00% | −7,591−7.1% | Reduced |
| Citadel Advisors LLC | 100,395 | $7.97M | 0.01% | +50,001+99.2% | Added |
| Catalio Capital Management, LP | 110,427 | $8.77M | 1.55% | −106,100−49.0% | Reduced |
| Sofinnova Investments, Inc. | 111,010 | $8.82M | 0.38% | +97,457+719.1% | Added |
| UBS Asset Management Americas Inc | 114,351 | $9.08M | 0.00% | +22,971+25.1% | Added |
| UBS Group AG | 116,112 | $9.22M | 0.00% | −55,511−32.3% | Reduced |
| BNP Paribas Arbitrage, SA | 122,153 | $9.70M | 0.01% | +84,543+224.8% | Added |
| Nantahala Capital Management, LLC | 132,800 | $10.5M | 0.63% | −155,000−53.9% | Reduced |
| Bank of America Corp | 135,986 | $10.8M | 0.00% | −25,198−15.6% | Reduced |
| First Turn Management, LLC | 153,206 | $12.2M | 1.39% | −244,487−61.5% | Reduced |
| Ensign Peak Advisors, Inc | 177,050 | $14.1M | 0.02% | 00.0% | Unchanged |
| Millennium Management LLC | 184,779 | $14.7M | 0.01% | +23,779+14.8% | Added |
| TimesSquare Capital Management, LLC | 187,777 | $14.9M | 0.22% | +5,607+3.1% | Added |
| Opaleye Management Inc. | 200,000 | $15.9M | 2.10% | +6,227+3.2% | Added |
| Balyasny Asset Management LLC | 221,761 | $17.6M | 0.03% | −116,340−34.4% | Reduced |
| Dimensional Fund Advisors LP | 223,575 | $17.7M | 0.00% | −6,848−3.0% | Reduced |
| Northern Trust Corp | 228,070 | $18.1M | 0.00% | +8,581+3.9% | Added |
| Standard Life Aberdeen plc | 234,358 | $18.6M | 0.03% | +202,297+631.0% | Added |
| Charles Schwab Investment Management Inc | 247,039 | $19.6M | 0.00% | +20,384+9.0% | Added |
| Great Point Partners LLC | 250,000 | $19.9M | 6.44% | +250,000 | New |
| Loomis Sayles & Co L P | 282,409 | $22.4M | 0.03% | +282,409 | New |
| Saturn V Capital Management LLC | 298,429 | $23.7M | 4.35% | −42,468−12.5% | Reduced |
| Foresite Capital Management V, LLC | 299,069 | $23.7M | 14.45% | 00.0% | Unchanged |
| Palo Alto Investors LP | 317,456 | $25.2M | 3.51% | +93,156+41.5% | Added |
| Baker Bros. Advisors LP | 337,050 | $26.8M | 0.16% | 00.0% | Unchanged |
| Assenagon Asset Management S.A. | 357,836 | $28.4M | 0.04% | +347,403+3,329.8% | Added |
| Pictet Asset Management Holding SA | 394,374 | $31.3M | 0.03% | +390,811+10,968.6% | Added |
| Eventide Asset Management, LLC | 395,392 | $31.4M | 0.49% | +87,349+28.4% | Added |
| Perceptive Advisors LLC | 450,743 | $35.8M | 0.66% | +450,743 | New |
| Checkpoint Capital L.P. | 452,992 | $36.0M | 11.40% | +22,992+5.3% | Added |
| Armistice Capital, LLC | 499,391 | $39.7M | 0.97% | +63,391+14.5% | Added |
| Logos Global Management LP | 510,000 | $40.5M | 2.70% | +60,000+13.3% | Added |
| Deerfield Management Company, L.P. (Series C) | 511,163 | $40.6M | 0.52% | −408,240−44.4% | Reduced |
| First Light Asset Management, LLC | 523,167 | $41.5M | 3.18% | +291,981+126.3% | Added |
| Jennison Associates LLC | 532,079 | $42.3M | 0.03% | +532,079 | New |
| BVF Inc | 650,000 | $51.6M | 1.74% | +650,000 | New |
| Geode Capital Management, LLC | 684,958 | $54.4M | 0.00% | +56,807+9.0% | Added |
| Vestal Point Capital, LP | 735,000 | $58.4M | 2.14% | +235,000+47.0% | Added |
| Goldman Sachs Group Inc | 754,195 | $59.9M | 0.01% | +225,114+42.5% | Added |
| Woodline Partners LP | 957,833 | $76.1M | 0.29% | +90,878+10.5% | Added |
| Siren, L.L.C. | 988,401 | $78.5M | 2.34% | +75,000+8.2% | Added |
| OrbiMed Advisors LLC | 1,067,550 | $84.8M | 1.73% | −347,470−24.6% | Reduced |
| State Street Corp | 1,187,991 | $94.3M | 0.00% | +142,394+13.6% | Added |
| Frazier Life Sciences Management, L.P. | 1,260,000 | $100.1M | 2.69% | −178,534−12.4% | Reduced |
| Atlas Venture Life Science Advisors, LLC | 1,513,875 | $120.2M | 13.90% | −628,742−29.3% | Reduced |
| Wellington Management Group LLP | 1,518,274 | $120.6M | 0.02% | +108,197+7.7% | Added |
| JPMorgan Chase & Co | 1,581,127 | $125.6M | 0.01% | +828,248+110.0% | Added |
| Price T Rowe Associates Inc | 1,698,005 | $134.8M | 0.01% | +371,576+28.0% | Added |
| Vanguard Group Inc | 1,767,680 | $140.4M | 0.00% | +319,621+22.1% | Added |
| Ra Capital Management, L.P. | 1,976,132 | $156.9M | 1.61% | +399,026+25.3% | Added |
| BlackRock, Inc. | 2,274,980 | $180.7M | 0.00% | +255,697+12.7% | Added |
| FMR LLC | 5,450,222 | $432.8M | 0.02% | +515,063+10.4% | Added |
| TCG Crossover Management, LLC | 0 | $0 | 0.00% | −465,257−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −450,000−100.0% | Sold out |
| Paradigm Biocapital Advisors LP | 0 | $0 | 0.00% | −247,716−100.0% | Sold out |