Iovance Biotherapeutics, Inc.
IOVA- Exchange
- Nasdaq
- Industry
- Biological Products, (No Diagnostic Substances)
- SEC CIK
- 0001425205
No open-market purchases or sales by Iovance Biotherapeutics, Inc. insiders were filed in the last 90 days; 293 institutions reported holding it in 13F filings for Q2 2026, worth $1.19B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Iovance Biotherapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 263
- +15 vs. Q3 2025
- Shares held
- 261.6M
- +48.6M (+22.8%) vs. Q3 2025
- Total value
- $713.7M
- +$251.6M (+54.4%) vs. Q3 2025
- New holders
- 51
- 103 more added
- Sold out
- 36
- 63 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting IOVA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 293 | $1.19B |
| Q1 2026 | 286 | $943.8M |
| Q4 2025 | 263 | $713.7M |
| Q3 2025 | 253 | $462.3M |
| Q2 2025 | 255 | $379.3M |
| Q1 2025 | 303 | $798.9M |
| Q4 2024 | 302 | $1.79B |
| Q3 2024 | 286 | $2.21B |
| Q2 2024 | 295 | $1.86B |
| Q1 2024 | 273 | $3.22B |
| Q4 2023 | 236 | $1.69B |
| Q3 2023 | 228 | $970.0M |
| Q2 2023 | 219 | $1.44B |
| Q1 2023 | 230 | $1.25B |
| Q4 2022 | 218 | $1.11B |
| Q3 2022 | 242 | $1.48B |
| Q2 2022 | 238 | $1.75B |
| Q1 2022 | 248 | $2.60B |
| Q4 2021 | 246 | $2.96B |
| Q3 2021 | 244 | $3.88B |
| Q2 2021 | 234 | $4.22B |
| Q1 2021 | 252 | $4.98B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Iovance Biotherapeutics, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| BlackRock, Inc. | 29,518,125 | $80.6M | 0.00% | +3,561,836+13.7% | Added |
| MHR Fund Management LLC | 28,967,103 | $79.1M | 6.81% | 00.0% | Unchanged |
| Vanguard Group Inc | 27,207,079 | $74.3M | 0.00% | +3,148,096+13.1% | Added |
| State Street Corp | 20,161,445 | $55.0M | 0.00% | +6,851,486+51.5% | Added |
| Bank of America Corp | 14,277,813 | $39.0M | 0.00% | +7,998,583+127.4% | Added |
| Invenomic Capital Management LP | 11,959,505 | $32.6M | 1.58% | +1,417,897+13.5% | Added |
| Morgan Stanley | 9,191,840 | $25.1M | 0.00% | +3,610,277+64.7% | Added |
| Goldman Sachs Group Inc | 8,607,564 | $23.5M | 0.00% | +2,032,062+30.9% | Added |
| Long Focus Capital Management, LLC | 8,600,000 | $23.5M | 1.17% | −516,507−5.7% | Reduced |
| Geode Capital Management, LLC | 7,991,640 | $21.8M | 0.00% | +1,123,337+16.4% | Added |
| Palo Alto Investors LP | 7,116,676 | $19.4M | 2.70% | −501,456−6.6% | Reduced |
| Millennium Management LLC | 6,585,532 | $18.0M | 0.01% | +2,172,081+49.2% | Added |
| Susquehanna International Group, LLP | 4,948,614 | $13.5M | 0.02% | +1,642,098+49.7% | Added |
| Two Sigma Investments, LP | 4,397,989 | $12.0M | 0.02% | +1,657,135+60.5% | Added |
| HRT Financial LP | 4,356,010 | $11.9M | 0.04% | +3,986,314+1,078.3% | Added |
| D. E. Shaw & Co., Inc. | 3,829,795 | $10.5M | 0.01% | +3,753,586+4,925.4% | Added |
| Jane Street Group, LLC | 3,583,810 | $9.78M | 0.01% | +2,170,148+153.5% | Added |
| Citadel Advisors LLC | 3,143,091 | $8.58M | 0.01% | −677,273−17.7% | Reduced |
| Two Sigma Advisers, LP | 3,015,000 | $8.23M | 0.02% | +1,956,000+184.7% | Added |
| JPMorgan Chase & Co | 3,001,502 | $8.19M | 0.00% | +1,777,671+145.3% | Added |
| Charles Schwab Investment Management Inc | 2,753,343 | $7.52M | 0.00% | +248,801+9.9% | Added |
| Northern Trust Corp | 2,579,594 | $7.04M | 0.00% | +118,521+4.8% | Added |
| Wells Fargo & Company | 1,993,337 | $5.44M | 0.00% | +475,973+31.4% | Added |
| Orion Investment Co | 1,856,934 | $5.07M | 1.55% | +5,150+0.3% | Added |
| Rhenman & Partners Asset Management AB | 1,595,327 | $4.36M | 0.41% | +497,500+45.3% | Added |
| Dimensional Fund Advisors LP | 1,539,110 | $4.20M | 0.00% | −1,283,648−45.5% | Reduced |
| B Group, Inc. | 1,500,000 | $4.09M | 3.03% | 00.0% | Unchanged |
| Rice Hall James & Associates, LLC | 1,425,088 | $3.89M | 0.21% | −26,284−1.8% | Reduced |
| Nuveen, LLC | 1,385,988 | $3.78M | 0.00% | +134,507+10.7% | Added |
| C WorldWide Group Holding A/S | 1,260,000 | $3.44M | 0.06% | 00.0% | Unchanged |
| Invesco Ltd. | 1,251,665 | $3.42M | 0.00% | +306,195+32.4% | Added |
| Price T Rowe Associates Inc | 1,191,828 | $3.25M | 0.00% | −866,190−42.1% | Reduced |
| Barclays PLC | 1,127,157 | $3.08M | 0.00% | +190,470+20.3% | Added |
| Mirador Capital Partners LP | 1,034,544 | $2.82M | 0.39% | +519,519+100.9% | Added |
| Bank of New York Mellon Corp | 955,467 | $2.61M | 0.00% | +148,283+18.4% | Added |
| Susquehanna Portfolio Strategies, LLC | 914,449 | $2.50M | 0.04% | +2,350+0.3% | Added |
| Gsa Capital Partners LLP | 872,985 | $2.38M | 0.21% | +793,763+1,001.9% | Added |
| Walleye Capital LLC | 822,754 | $2.25M | 0.01% | +786,077+2,143.2% | Added |
| UBS Group AG | 764,154 | $2.09M | 0.00% | −172,350−18.4% | Reduced |
| Standard Life Aberdeen plc | 759,522 | $2.07M | 0.00% | +152,312+25.1% | Added |
| Rafferty Asset Management, LLC | 706,450 | $1.93M | 0.01% | +223,475+46.3% | Added |
| Deutsche Bank AG | 690,416 | $1.88M | 0.00% | +44,960+7.0% | Added |
| QVT Financial LP | 678,564 | $1.85M | 0.18% | 00.0% | Unchanged |
| Renaissance Technologies LLC | 651,000 | $1.78M | 0.00% | +651,000 | New |
| Voleon Capital Management LP | 630,257 | $1.72M | 0.04% | +490,288+350.3% | Added |
| Healthcare of Ontario Pension Plan Trust Fund | 628,537 | $1.72M | 0.00% | +497,537+379.8% | Added |
| LPL Financial LLC | 623,072 | $1.70M | 0.00% | +11,675+1.9% | Added |
| Royal Bank of Canada | 608,459 | $1.66M | 0.00% | −946,354−60.9% | Reduced |
| Swiss National Bank | 606,456 | $1.66M | 0.00% | +88,400+17.1% | Added |
| Woodline Partners LP | 567,680 | $1.55M | 0.01% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 564,519 | $1.54M | 0.00% | +564,519 | New |
| Brevan Howard Capital Management LP | 525,519 | $1.43M | 0.03% | +253,552+93.2% | Added |
| XTX Topco Ltd | 522,934 | $1.43M | 0.04% | +312,413+148.4% | Added |
| UBS Asset Management Americas Inc | 469,706 | $1.28M | 0.00% | −12,075−2.5% | Reduced |
| Rhumbline Advisers | 461,284 | $1.26M | 0.00% | +67,207+17.1% | Added |
| Cresset Asset Management, LLC | 457,786 | $1.25M | 0.01% | +267,300+140.3% | Added |
| Raiffeisen Bank International AG | 450,000 | $1.25M | 0.02% | +210,000+87.5% | Added |
| Algert Global LLC | 433,999 | $1.18M | 0.02% | +433,999 | New |
| Hennion & Walsh Asset Management, Inc. | 410,206 | $1.12M | 0.04% | −134,147−24.6% | Reduced |
| Raymond James Financial Inc | 404,441 | $1.10M | 0.00% | +68,285+20.3% | Added |
| CM Management, LLC | 400,000 | $1.09M | 0.92% | −300,000−42.9% | Reduced |
| Stifel Financial Corp | 329,815 | $900.4K | 0.00% | −19,780−5.7% | Reduced |
| Simplex Trading, LLC | 329,063 | $898.3K | 0.03% | +46,903+16.6% | Added |
| Quadrature Capital Ltd | 318,703 | $870.1K | 0.01% | +318,703 | New |
| Kennondale Capital Management LLC | 318,188 | $868.7K | 0.64% | 00.0% | Unchanged |
| Jain Global LLC | 312,096 | $852.0K | 0.01% | +312,096 | New |
| Virtus Investment Advisers, Inc. | 310,641 | $848.0K | 0.23% | +118,263+61.5% | Added |
| Corsair Capital Management, L.P. | 300,000 | $819.0K | 0.14% | +300,000 | New |
| California State Teachers Retirement System | 295,997 | $808.1K | 0.00% | +45,058+18.0% | Added |
| ExodusPoint Capital Management, LP | 281,477 | $768.4K | 0.01% | +239,354+568.2% | Added |
| Profund Advisors LLC | 260,660 | $711.6K | 0.02% | +156,253+149.7% | Added |
| Alliancebernstein L.P. | 258,890 | $706.8K | 0.00% | 00.0% | Unchanged |
| Legal & General Group Plc | 258,676 | $706.2K | 0.00% | +4,114+1.6% | Added |
| Manufacturers Life Insurance Company, The | 231,443 | $637.3K | 0.00% | +6,228+2.8% | Added |
| Scientech Research LLC | 211,477 | $577.3K | 0.36% | +211,477 | New |
| Russell Investments Group, Ltd. | 198,043 | $540.7K | 0.00% | +131,072+195.7% | Added |
| Parametrica Management Ltd | 195,878 | $534.7K | 0.82% | 00.0% | Unchanged |
| Leonteq Securities AG | 195,000 | $532.4K | 0.03% | +100,000+105.3% | Added |
| Engineers Gate Manager LP | 194,691 | $531.5K | 0.01% | +194,691 | New |
| Mirae Asset Global ETFs Holdings Ltd. | 183,968 | $503.9K | 0.00% | +39,052+26.9% | Added |
| HSBC Holdings PLC | 180,541 | $497.4K | 0.00% | +156,517+651.5% | Added |
| Capital Fund Management S.A. | 181,074 | $494.3K | 0.00% | −120,004−39.9% | Reduced |
| Tudor Investment Corp Et Al | 179,494 | $490.0K | 0.00% | +57,750+47.4% | Added |
| MetLife Investment Management | 170,782 | $466.2K | 0.00% | +29,096+20.5% | Added |
| Group One Trading, L.P. | 168,677 | $460.5K | 0.01% | −261,177−60.8% | Reduced |
| EFG International AG | 168,000 | $458.6K | 0.01% | +168,000 | New |
| Creative Planning | 158,653 | $433.1K | 0.00% | +59,425+59.9% | Added |
| Baird Financial Group, Inc. | 157,540 | $430.1K | 0.00% | −4,035−2.5% | Reduced |
| Perceptive Advisors LLC | 152,714 | $416.9K | 0.01% | +152,714 | New |
| Quantitative Investment Management, LLC | 138,583 | $378.0K | 0.04% | +138,583 | New |
| Intech Investment Management LLC | 136,763 | $373.4K | 0.00% | +10,948+8.7% | Added |
| Intellectus Partners, LLC | 132,446 | $361.6K | 0.07% | +1,384+1.1% | Added |
| Portland Investment Counsel Inc. | 130,000 | $354.9K | 0.11% | 00.0% | Unchanged |
| American Century Companies Inc | 129,088 | $352.4K | 0.00% | +100,624+353.5% | Added |
| MML Investors Services, LLC | 111,848 | $305.3K | 0.00% | +111,848 | New |
| AQR Capital Management LLC | 110,591 | $301.9K | 0.00% | +9,193+9.1% | Added |
| Sugar Maple Asset Management, LLC | 110,000 | $300.3K | 0.20% | +110,000 | New |
| State of Wisconsin Investment Board | 109,997 | $300.3K | 0.00% | −5,041−4.4% | Reduced |
| SEI Investments Co | 105,636 | $288.4K | 0.00% | +76,976+268.6% | Added |
| Citigroup Inc | 105,540 | $288.1K | 0.00% | −304,025−74.2% | Reduced |