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Iovance Biotherapeutics, Inc.

IOVA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001425205

No open-market purchases or sales by Iovance Biotherapeutics, Inc. insiders were filed in the last 90 days; 293 institutions reported holding it in 13F filings for Q2 2026, worth $1.19B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Iovance Biotherapeutics, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
253
+1 vs. Q2 2025
Shares held
213.0M
−7.19M (−3.3%) vs. Q2 2025
Total value
$462.3M
+$83.1M (+21.9%) vs. Q2 2025
New holders
41
81 more added
Sold out
40
79 more reduced

3 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IOVA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 253 institutions
Q1 2021: 252 institutionsQ2 2021: 234 institutionsQ3 2021: 244 institutionsQ4 2021: 246 institutionsQ1 2022: 248 institutionsQ2 2022: 238 institutionsQ3 2022: 242 institutionsQ4 2022: 218 institutionsQ1 2023: 230 institutionsQ2 2023: 219 institutionsQ3 2023: 228 institutionsQ4 2023: 236 institutionsQ1 2024: 273 institutionsQ2 2024: 295 institutionsQ3 2024: 286 institutionsQ4 2024: 302 institutionsQ1 2025: 303 institutionsQ2 2025: 255 institutionsQ3 2025: 253 institutionsQ4 2025: 263 institutionsQ1 2026: 286 institutionsQ2 2026: 293 institutions
Value heldQ3 2025: $462.3M
Q1 2021: $4.98BQ2 2021: $4.22BQ3 2021: $3.88BQ4 2021: $2.96BQ1 2022: $2.60BQ2 2022: $1.75BQ3 2022: $1.48BQ4 2022: $1.11BQ1 2023: $1.25BQ2 2023: $1.44BQ3 2023: $970.0MQ4 2023: $1.69BQ1 2024: $3.22BQ2 2024: $1.86BQ3 2024: $2.21BQ4 2024: $1.79BQ1 2025: $798.9MQ2 2025: $379.3MQ3 2025: $462.3MQ4 2025: $713.7MQ1 2026: $943.8MQ2 2026: $1.19B
Institutions holding IOVA and their total value by quarter
QuarterHoldersValue
Q2 2026293$1.19B
Q1 2026286$943.8M
Q4 2025263$713.7M
Q3 2025253$462.3M
Q2 2025255$379.3M
Q1 2025303$798.9M
Q4 2024302$1.79B
Q3 2024286$2.21B
Q2 2024295$1.86B
Q1 2024273$3.22B
Q4 2023236$1.69B
Q3 2023228$970.0M
Q2 2023219$1.44B
Q1 2023230$1.25B
Q4 2022218$1.11B
Q3 2022242$1.48B
Q2 2022238$1.75B
Q1 2022248$2.60B
Q4 2021246$2.96B
Q3 2021244$3.88B
Q2 2021234$4.22B
Q1 2021252$4.98B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Iovance Biotherapeutics, Inc.; share changes are against Q2 2025.

Institutions holding IOVA in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
MHR Fund Management LLC28,967,103$62.9M6.16%00.0%Unchanged
BlackRock, Inc.25,956,289$56.3M0.00%+2,719,477+11.7%Added
Vanguard Group Inc24,058,983$52.2M0.00%−1,017,489−4.1%Reduced
State Street Corp13,309,959$28.9M0.00%+3,419,434+34.6%Added
Invenomic Capital Management LP10,541,608$22.9M1.20%+2,246,945+27.1%Added
Long Focus Capital Management, LLC9,116,507$19.8M1.13%−2,703,493−22.9%Reduced
Palo Alto Investors LP7,618,132$16.5M3.06%+4,188,803+122.1%Added
Geode Capital Management, LLC6,868,303$14.9M0.00%+679,245+11.0%Added
Goldman Sachs Group Inc6,575,502$14.3M0.00%+1,825,626+38.4%Added
Bank of America Corp6,279,230$13.6M0.00%+2,249,662+55.8%Added
Morgan Stanley5,581,563$12.1M0.00%−869,370−13.5%Reduced
Millennium Management LLC4,413,451$9.58M0.01%−4,916,772−52.7%Reduced
Citadel Advisors LLC3,820,364$8.29M0.01%−293,224−7.1%Reduced
Susquehanna International Group, LLP3,306,516$7.18M0.01%+1,235,044+59.6%Added
Principal Financial Group Inc3,013,753$6.54M0.00%−1,587,688−34.5%Reduced
Dimensional Fund Advisors LP2,822,758$6.13M0.00%−105,978−3.6%Reduced
Two Sigma Investments, LP2,740,854$5.95M0.01%−1,892,597−40.8%Reduced
Charles Schwab Investment Management Inc2,504,542$5.43M0.00%+588,056+30.7%Added
Northern Trust Corp2,461,073$5.34M0.00%+341,286+16.1%Added
Price T Rowe Associates Inc2,058,018$4.47M0.00%−56,172−2.7%Reduced
Orion Investment Co1,851,784$4.02M1.28%−486,779−20.8%Reduced
Royal Bank of Canada1,554,813$3.38M0.00%−824,275−34.6%Reduced
Wells Fargo & Company1,517,364$3.29M0.00%+443,114+41.2%Added
B Group, Inc.1,500,000$3.25M3.11%00.0%Unchanged
Rice Hall James & Associates, LLC1,451,372$3.15M0.17%−140,203−8.8%Reduced
Jane Street Group, LLC1,413,662$3.07M0.00%−593,909−29.6%Reduced
C WorldWide Group Holding A/S1,260,000$2.73M0.04%00.0%Unchanged
Nuveen, LLC1,251,481$2.72M0.00%+472,731+60.7%Added
JPMorgan Chase & Co1,223,831$2.66M0.00%−19,040−1.5%Reduced
Rhenman & Partners Asset Management AB1,097,827$2.38M0.26%+450,000+69.5%Added
Two Sigma Advisers, LP1,059,000$2.30M0.00%−1,275,900−54.6%Reduced
Soleus Capital Management, L.P.976,707$2.12M0.11%−2,285,000−70.1%Reduced
Invesco Ltd.945,470$2.05M0.00%+291,521+44.6%Added
Barclays PLC936,687$2.03M0.00%+52,347+5.9%Added
UBS Group AG936,504$2.03M0.00%−842,908−47.4%Reduced
Susquehanna Portfolio Strategies, LLC912,099$1.98M0.03%+912,099New
Bank of New York Mellon Corp807,184$1.75M0.00%+26,557+3.4%Added
CM Management, LLC700,000$1.52M1.27%00.0%Unchanged
QVT Financial LP678,564$1.47M0.16%00.0%Unchanged
Voss Capital, LLC650,000$1.41M0.08%−22,570−3.4%Reduced
Deutsche Bank AG645,456$1.40M0.00%+25,010+4.0%Added
LPL Financial LLC611,397$1.33M0.00%+127,070+26.2%Added
Standard Life Aberdeen plc607,210$1.32M0.00%+90,921+17.6%Added
Woodline Partners LP567,680$1.23M0.01%00.0%Unchanged
Hennion & Walsh Asset Management, Inc.544,353$1.18M0.04%+45,101+9.0%Added
Tang Capital Management LLC543,760$1.18M0.05%−1,256,240−69.8%Reduced
Swiss National Bank518,056$1.12M0.00%+16,900+3.4%Added
Mirador Capital Partners LP515,025$1.12M0.16%+515,025New
Rafferty Asset Management, LLC482,975$1.05M0.00%+190,522+65.1%Added
UBS Asset Management Americas Inc481,781$1.05M0.00%−175,428−26.7%Reduced
Group One Trading, L.P.429,854$932.8K0.03%−123,614−22.3%Reduced
Citigroup Inc409,565$888.8K0.00%−305,286−42.7%Reduced
Rhumbline Advisers394,077$855.1K0.00%−16,418−4.0%Reduced
HRT Financial LP369,696$802.0K0.00%+301,434+441.6%Added
Stifel Financial Corp349,595$758.6K0.00%+123,955+54.9%Added
Raymond James Financial Inc336,156$729.5K0.00%+12,058+3.7%Added
Kennondale Capital Management LLC318,188$690.5K0.53%+95,134+42.7%Added
Capital Fund Management S.A.301,078$653.3K0.01%−73,835−19.7%Reduced
Simplex Trading, LLC282,160$612.0K0.01%−4,429−1.5%Reduced
Brevan Howard Capital Management LP271,967$590.2K0.01%−89,836−24.8%Reduced
Alliancebernstein L.P.258,890$561.8K0.00%00.0%Unchanged
Legal & General Group Plc254,562$552.4K0.00%+21,865+9.4%Added
California State Teachers Retirement System250,939$544.5K0.00%+67,823+37.0%Added
Raiffeisen Bank International AG240,000$535.2K0.01%+93,000+63.3%Added
Manufacturers Life Insurance Company, The225,215$488.7K0.00%−48,771−17.8%Reduced
XTX Topco Ltd210,521$456.8K0.02%+170,385+424.5%Added
Parametrica Management Ltd195,878$425.1K0.66%00.0%Unchanged
Cinctive Capital Management LP195,290$423.8K0.02%+195,290New
Virtus Investment Advisers, Inc.192,378$417.5K0.12%00.0%Unchanged
Cresset Asset Management, LLC190,486$413.4K0.00%+213+0.1%Added
NEOS Investment Management LLC173,872$377.3K0.00%+173,872New
Tema ETFs LLC173,872$377.3K0.03%+173,872New
Baird Financial Group, Inc.161,575$350.6K0.00%−28,270−14.9%Reduced
Quinn Opportunity Partners LLC160,000$347.2K0.03%−454,200−73.9%Reduced
Mirae Asset Global ETFs Holdings Ltd.144,916$315.9K0.00%−9,781−6.3%Reduced
MetLife Investment Management141,686$307.5K0.00%−9,288−6.2%Reduced
Voleon Capital Management LP139,969$303.7K0.01%−369,699−72.5%Reduced
TD Asset Management Inc139,878$303.5K0.00%00.0%Unchanged
Intellectus Partners, LLC131,062$284.4K0.06%00.0%Unchanged
Healthcare of Ontario Pension Plan Trust Fund131,000$284.3K0.00%+131,000New
Portland Investment Counsel Inc.130,000$282.1K0.08%00.0%Unchanged
Intech Investment Management LLC125,815$273.0K0.00%−45,860−26.7%Reduced
DnB Asset Management AS124,045$269.2K0.00%−39,460−24.1%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.123,845$268.7K0.00%+247+0.2%Added
Tudor Investment Corp Et Al121,744$264.2K0.00%+121,744New
State of Wisconsin Investment Board115,038$249.6K0.00%+7,079+6.6%Added
Atom Investors LP113,921$247.2K0.02%+113,921New
Guggenheim Capital LLC110,380$239.5K0.00%−12,487−10.2%Reduced
Advisor Group Holdings, Inc.106,404$236.6K0.00%+17,548+19.7%Added
Profund Advisors LLC104,407$226.6K0.01%+41,559+66.1%Added
AQR Capital Management LLC101,398$220.0K0.00%−130,259−56.2%Reduced
Creative Planning99,228$215.3K0.00%+23,234+30.6%Added
DekaBank Deutsche Girozentrale100,000$215.0K0.00%00.0%Unchanged
Handelsbanken Fonder AB96,900$210.0K0.00%00.0%Unchanged
Leonteq Securities AG95,000$206.2K0.01%00.0%Unchanged
Janus Henderson Group PLC91,341$198.7K0.00%00.0%Unchanged
Balyasny Asset Management LLC90,624$196.7K0.00%−1,417,158−94.0%Reduced
Virginia Retirement Systems Et Al82,300$178.6K0.00%+82,300New
Gsa Capital Partners LLP79,222$172.0K0.01%−117,385−59.7%Reduced
Arizona State Retirement System78,850$171.1K0.00%+2,717+3.6%Added