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Iovance Biotherapeutics, Inc.

IOVA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001425205

No open-market purchases or sales by Iovance Biotherapeutics, Inc. insiders were filed in the last 90 days; 293 institutions reported holding it in 13F filings for Q2 2026, worth $1.19B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Iovance Biotherapeutics, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
246
+5 vs. Q3 2021
Shares held
155.9M
−2.08M (−1.3%) vs. Q3 2021
Total value
$2.96B
−$919.0M (−23.7%) vs. Q3 2021
New holders
40
95 more added
Sold out
35
85 more reduced

3 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IOVA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 246 institutions
Q1 2021: 252 institutionsQ2 2021: 234 institutionsQ3 2021: 244 institutionsQ4 2021: 246 institutionsQ1 2022: 248 institutionsQ2 2022: 238 institutionsQ3 2022: 242 institutionsQ4 2022: 218 institutionsQ1 2023: 230 institutionsQ2 2023: 219 institutionsQ3 2023: 228 institutionsQ4 2023: 236 institutionsQ1 2024: 273 institutionsQ2 2024: 295 institutionsQ3 2024: 286 institutionsQ4 2024: 302 institutionsQ1 2025: 303 institutionsQ2 2025: 255 institutionsQ3 2025: 253 institutionsQ4 2025: 263 institutionsQ1 2026: 286 institutionsQ2 2026: 293 institutions
Value heldQ4 2021: $2.96B
Q1 2021: $4.98BQ2 2021: $4.22BQ3 2021: $3.88BQ4 2021: $2.96BQ1 2022: $2.60BQ2 2022: $1.75BQ3 2022: $1.48BQ4 2022: $1.11BQ1 2023: $1.25BQ2 2023: $1.44BQ3 2023: $970.0MQ4 2023: $1.69BQ1 2024: $3.22BQ2 2024: $1.86BQ3 2024: $2.21BQ4 2024: $1.79BQ1 2025: $798.9MQ2 2025: $379.3MQ3 2025: $462.3MQ4 2025: $713.7MQ1 2026: $943.8MQ2 2026: $1.19B
Institutions holding IOVA and their total value by quarter
QuarterHoldersValue
Q2 2026293$1.19B
Q1 2026286$943.8M
Q4 2025263$713.7M
Q3 2025253$462.3M
Q2 2025255$379.3M
Q1 2025303$798.9M
Q4 2024302$1.79B
Q3 2024286$2.21B
Q2 2024295$1.86B
Q1 2024273$3.22B
Q4 2023236$1.69B
Q3 2023228$970.0M
Q2 2023219$1.44B
Q1 2023230$1.25B
Q4 2022218$1.11B
Q3 2022242$1.48B
Q2 2022238$1.75B
Q1 2022248$2.60B
Q4 2021246$2.96B
Q3 2021244$3.88B
Q2 2021234$4.22B
Q1 2021252$4.98B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Iovance Biotherapeutics, Inc.; share changes are against Q3 2021.

Institutions holding IOVA in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc12,197,787$232.9M0.01%+268,798+2.3%Added
Perceptive Advisors LLC10,127,941$193.3M2.99%−1,361,831−11.9%Reduced
Wellington Management Group LLP9,584,082$183.0M0.03%+684,552+7.7%Added
Avoro Capital Advisors LLC8,675,000$165.6M2.82%+175,000+2.1%Added
BlackRock Inc.7,408,505$141.4M0.00%+460,699+6.6%Added
ARK Investment Management LLCSuperinvestorARK Invest7,201,518$137.5M0.42%−4,448,319−38.2%Reduced
OrbiMed Advisors LLC6,337,700$121.0M1.57%−307,400−4.6%Reduced
Farallon Capital Management, L.L.C.6,061,973$115.7M0.65%+721,979+13.5%Added
Franklin Resources Inc5,797,716$110.7M0.04%−471,707−7.5%Reduced
State Street Corp5,093,682$97.2M0.00%+705,576+16.1%Added
Sumitomo Mitsui Trust Holdings, Inc.4,965,096$94.8M0.06%−1,415,707−22.2%Reduced
Price T Rowe Associates Inc4,663,785$89.0M0.01%+39,057+0.8%Added
Nikko Asset Management Americas, Inc.4,965,096$82.6M0.43%−1,415,707−22.2%Reduced
Avidity Partners Management LP3,780,000$72.2M1.53%+2,317,800+158.5%Added
Armistice Capital, LLC3,000,000$57.3M1.39%−648,000−17.8%Reduced
Artisan Partners Limited Partnership2,687,730$51.3M0.06%−180,565−6.3%Reduced
Ameriprise Financial Inc2,469,709$47.1M0.01%+298,109+13.7%Added
Credit Suisse AG2,436,816$46.5M0.04%+21,203+0.9%Added
Pictet Asset Management SA2,211,132$42.2M0.04%+1,213,057+121.5%Added
FMR LLC2,026,166$38.7M0.00%+75,548+3.9%Added
JPMorgan Chase & Co2,017,431$38.5M0.00%+378,695+23.1%Added
Geode Capital Management, LLC1,847,811$35.3M0.00%+61,799+3.5%Added
Frazier Management LLC1,747,622$33.4M2.57%−926,677−34.7%Reduced
Bank of New York Mellon Corp1,667,094$31.8M0.01%−51,839−3.0%Reduced
Invesco Ltd.1,587,067$30.3M0.01%+560,410+54.6%Added
Goldman Sachs Group Inc1,449,804$27.7M0.01%+194,704+15.5%Added
Norges Bank1,301,450$24.8M0.01%+63,252+5.1%Added
Boxer Capital, LLC1,100,000$21.0M0.84%00.0%Unchanged
Lombard Odier Asset Management (Switzerland) SA949,884$18.1M1.16%+80,344+9.2%Added
Candriam Luxembourg S.C.A.896,364$17.1M0.11%+47,712+5.6%Added
Dimensional Fund Advisors LP884,481$16.9M0.01%+553,559+167.3%Added
Marshall Wace, LLP861,160$16.4M0.03%+861,160New
Paradigm Biocapital Advisors LP844,005$16.1M4.60%+844,005New
Novo Holdings A/S836,518$16.0M0.76%00.0%Unchanged
Balyasny Asset Management LLC796,835$15.2M0.06%−166,625−17.3%Reduced
Bank of America Corp790,884$15.1M0.00%+234,814+42.2%Added
Senator Investment Group LP750,000$14.3M0.28%+250,000+50.0%Added
683 Capital Management, LLC720,000$13.7M0.65%−229,829−24.2%Reduced
Susquehanna International Group, LLP695,000$13.3M0.02%+73,961+11.9%Added
Charles Schwab Investment Management Inc685,459$13.1M0.00%+19,563+2.9%Added
QVT Financial LP678,564$13.0M0.46%00.0%Unchanged
Nuveen Asset Management, LLC677,207$12.9M0.00%+61,929+10.1%Added
Rice Hall James & Associates, LLC631,784$12.1M0.43%−230,163−26.7%Reduced
Rothschild & Co Asset Management US Inc.629,613$12.0M0.14%+95,526+17.9%Added
Woodline Partners LP618,703$11.8M0.17%+433,151+233.4%Added
Rhenman & Partners Asset Management AB600,000$11.7M0.77%+280,000+87.5%Added
Northern Trust Corp607,502$11.6M0.00%−14,712−2.4%Reduced
Voloridge Investment Management, LLC603,676$11.5M0.06%−34,758−5.4%Reduced
Principal Financial Group Inc561,587$10.7M0.01%+14,720+2.7%Added
Frontier Capital Management Co LLC537,297$10.3M0.08%−139,645−20.6%Reduced
Banque Pictet & Cie SA534,036$10.2M0.08%+467,364+701.0%Added
Aristotle Atlantic Partners, LLC525,538$10.0M0.58%+525,538New
Long Focus Capital Management, LLC525,000$10.0M2.73%+525,000New
New York State Common Retirement Fund521,689$9.96M0.01%−109,864−17.4%Reduced
Kennedy Capital Management, Inc.412,700$7.88M0.17%−11,501−2.7%Reduced
American Century Companies Inc408,533$7.80M0.00%+31,379+8.3%Added
Ally Bridge Group (NY) LLC406,986$7.77M2.72%00.0%Unchanged
Fairmount Funds Management LLC389,588$7.44M2.45%00.0%Unchanged
Two Sigma Investments, LP381,881$7.29M0.02%+122,951+47.5%Added
Millennium Management LLC330,291$6.30M0.01%+330,291New
Vivo Capital, LLC301,000$5.75M0.35%+301,000New
California Public Employees Retirement System295,415$5.64M0.00%00.0%Unchanged
Victory Capital Management Inc292,777$5.59M0.01%−16,875−5.4%Reduced
Rafferty Asset Management, LLC285,506$5.45M0.03%+148,649+108.6%Added
Sphera Funds Management Ltd.281,769$5.38M0.64%−213,040−43.1%Reduced
Swiss National Bank272,856$5.21M0.00%+2,700+1.0%Added
Renaissance Technologies LLC270,000$5.15M0.01%+270,000New
SEI Investments Co266,771$5.09M0.01%+44,367+19.9%Added
Alliancebernstein L.P.253,707$4.84M0.00%+17,665+7.5%Added
Morgan Stanley253,575$4.84M0.00%−65,284−20.5%Reduced
Ensign Peak Advisors, Inc253,480$4.84M0.01%+59,666+30.8%Added
Peregrine Capital Management LLC251,850$4.81M0.10%+46,016+22.4%Added
Citadel Advisors LLC245,958$4.70M0.01%−1,107,605−81.8%Reduced
Citigroup Inc241,959$4.62M0.00%+119,208+97.1%Added
Walleye Capital LLC236,146$4.51M0.15%+236,146New
UBS Group AG219,537$4.19M0.00%+23,253+11.8%Added
Teachers Retirement System of the State of Kentucky215,933$4.12M0.04%+23,304+12.1%Added
State Board of Administration of Florida Retirement System209,449$4.00M0.01%+321+0.2%Added
Cubist Systematic Strategies, LLC187,785$3.58M0.03%−67,514−26.4%Reduced
California State Teachers Retirement System186,741$3.56M0.00%−40,222−17.7%Reduced
Acuta Capital Partners, LLC179,995$3.44M1.44%−194,500−51.9%Reduced
Parametric Portfolio Associates LLC179,666$3.43M0.00%−351,115−66.2%Reduced
Alps Advisors Inc179,419$3.42M0.04%−10,600−5.6%Reduced
UBS Asset Management Americas Inc178,061$3.40M0.00%+3,834+2.2%Added
Biondo Investment Advisors, LLC177,463$3.39M0.56%+626+0.4%Added
Ikarian Capital, LLC172,521$3.29M0.94%00.0%Unchanged
Jane Street Group, LLC169,617$3.24M0.01%+57,383+51.1%Added
WCM Investment Management, LLC166,941$3.19M0.01%+14,940+9.8%Added
Parametrica Management Ltd149,181$2.85M2.83%+2,819+1.9%Added
State of New Jersey Common Pension Fund D149,157$2.85M0.01%+19,779+15.3%Added
Tocqueville Asset Management L.P.140,940$2.69M0.04%−8,400−5.6%Reduced
TD Asset Management Inc138,724$2.65M0.00%+7,280+5.5%Added
Rhumbline Advisers134,519$2.57M0.00%+4,603+3.5%Added
Bank of Montreal129,063$2.51M0.00%+129,063New
Legal & General Group Plc126,888$2.42M0.00%+16,327+14.8%Added
Squarepoint Ops LLC123,591$2.36M0.01%+90,730+276.1%Added
Ergoteles LLC114,534$2.19M0.08%+2,700+2.4%Added
DekaBank Deutsche Girozentrale112,600$2.17M0.01%−15,000−11.8%Reduced
Toronto Dominion Bank112,026$2.14M0.00%+112,026New
Guggenheim Capital LLC104,596$2.00M0.01%+9,297+9.8%Added