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Iovance Biotherapeutics, Inc.

IOVA
Exchange
Nasdaq
Industry
Biological Products, (No Diagnostic Substances)
SEC CIK
0001425205

No open-market purchases or sales by Iovance Biotherapeutics, Inc. insiders were filed in the last 90 days; 293 institutions reported holding it in 13F filings for Q2 2026, worth $1.19B in total; no superinvestor holds it.

13F holders, Q4 2025

Institutional positions in Iovance Biotherapeutics, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
263
+15 vs. Q3 2025
Shares held
261.6M
+48.6M (+22.8%) vs. Q3 2025
Total value
$713.7M
+$251.6M (+54.4%) vs. Q3 2025
New holders
51
103 more added
Sold out
36
63 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting IOVA on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 263 institutions
Q1 2021: 252 institutionsQ2 2021: 234 institutionsQ3 2021: 244 institutionsQ4 2021: 246 institutionsQ1 2022: 248 institutionsQ2 2022: 238 institutionsQ3 2022: 242 institutionsQ4 2022: 218 institutionsQ1 2023: 230 institutionsQ2 2023: 219 institutionsQ3 2023: 228 institutionsQ4 2023: 236 institutionsQ1 2024: 273 institutionsQ2 2024: 295 institutionsQ3 2024: 286 institutionsQ4 2024: 302 institutionsQ1 2025: 303 institutionsQ2 2025: 255 institutionsQ3 2025: 253 institutionsQ4 2025: 263 institutionsQ1 2026: 286 institutionsQ2 2026: 293 institutions
Value heldQ4 2025: $713.7M
Q1 2021: $4.98BQ2 2021: $4.22BQ3 2021: $3.88BQ4 2021: $2.96BQ1 2022: $2.60BQ2 2022: $1.75BQ3 2022: $1.48BQ4 2022: $1.11BQ1 2023: $1.25BQ2 2023: $1.44BQ3 2023: $970.0MQ4 2023: $1.69BQ1 2024: $3.22BQ2 2024: $1.86BQ3 2024: $2.21BQ4 2024: $1.79BQ1 2025: $798.9MQ2 2025: $379.3MQ3 2025: $462.3MQ4 2025: $713.7MQ1 2026: $943.8MQ2 2026: $1.19B
Institutions holding IOVA and their total value by quarter
QuarterHoldersValue
Q2 2026293$1.19B
Q1 2026286$943.8M
Q4 2025263$713.7M
Q3 2025253$462.3M
Q2 2025255$379.3M
Q1 2025303$798.9M
Q4 2024302$1.79B
Q3 2024286$2.21B
Q2 2024295$1.86B
Q1 2024273$3.22B
Q4 2023236$1.69B
Q3 2023228$970.0M
Q2 2023219$1.44B
Q1 2023230$1.25B
Q4 2022218$1.11B
Q3 2022242$1.48B
Q2 2022238$1.75B
Q1 2022248$2.60B
Q4 2021246$2.96B
Q3 2021244$3.88B
Q2 2021234$4.22B
Q1 2021252$4.98B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Iovance Biotherapeutics, Inc.; share changes are against Q3 2025.

Institutions holding IOVA in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Advisor Group Holdings, Inc.102,155$278.9K0.00%−4,249−4.0%Reduced
Quinn Opportunity Partners LLC95,000$259.4K0.01%−65,000−40.6%Reduced
VARCOV Co.92,806$253.4K0.10%+92,806New
Janus Henderson Group PLC91,341$249.8K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)91,348$249.4K0.01%+72,357+381.0%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.98,605$248.5K0.00%−25,240−20.4%Reduced
Los Angeles Capital Management LLC119,860$233.7K0.00%+94,989+381.9%Added
Arizona State Retirement System85,490$233.4K0.00%+6,640+8.4%Added
Virginia Retirement Systems Et Al82,250$224.5K0.00%−50−0.1%Reduced
Police & Firemen's Retirement System of New Jersey76,002$207.5K0.00%−720−0.9%Reduced
ProShare Advisors LLC73,733$201.3K0.00%+16,194+28.1%Added
New York State Common Retirement Fund72,101$196.8K0.00%00.0%Unchanged
Cetera Investment Advisers70,674$192.9K0.00%−5,348−7.0%Reduced
Headlands Technologies LLC70,662$192.9K0.02%+70,662New
Balyasny Asset Management LLC68,038$185.7K0.00%−22,586−24.9%Reduced
Grandfield & Dodd, LLC65,930$180.0K0.01%−11,895−15.3%Reduced
State Board of Administration of Florida Retirement System65,451$178.7K0.00%00.0%Unchanged
WealthTrust Axiom LLC65,000$177.4K0.05%+25,000+62.5%Added
China Universal Asset Management Co., Ltd.64,686$176.6K0.01%+1,258+2.0%Added
KLP Kapitalforvaltning AS62,400$170.4K0.00%00.0%Unchanged
Haven Capital Group, Inc.59,143$161.0K0.15%−16,361−21.7%Reduced
SG Americas Securities, LLC55,389$151.0K0.00%+20,626+59.3%Added
Man Group plc54,521$148.8K0.00%+3,118+6.1%Added
Voya Investment Management LLC53,477$146.0K0.00%+6,300+13.4%Added
TD Asset Management Inc53,452$145.9K0.00%−86,426−61.8%Reduced
Centurion Wealth Management LLC52,384$143.0K0.03%−700−1.3%Reduced
Commonwealth Equity Services, LLC51,499$140.6K0.00%−151−0.3%Reduced
The PNC Financial Services Group, Inc.50,848$138.8K0.00%−208−0.4%Reduced
Rockefeller Capital Management L.P.50,726$138.5K0.00%+33,091+187.6%Added
Zurcher Kantonalbank (Zurich Cantonalbank)49,914$136.3K0.00%+15,992+47.1%Added
National Asset Management, Inc.48,000$131.0K0.01%+6,000+14.3%Added
Caitong International Asset Management Co., Ltd47,277$129.1K0.03%+41,047+658.9%Added
Assenagon Asset Management S.A.46,842$127.9K0.00%00.0%Unchanged
Captrust Financial Advisors46,812$127.8K0.00%+5,563+13.5%Added
Teacher Retirement System of Texas45,047$123.0K0.00%−19,739−30.5%Reduced
LMR Partners LLP41,211$112.5K0.00%00.0%Unchanged
Great West Life Assurance Co40,958$112.0K0.00%+6,933+20.4%Added
Chicago Partners Investment Group LLC40,589$107.2K0.00%+90.0%Added
Neuberger Berman Group LLC39,072$106.7K0.00%+5,605+16.7%Added
Victory Capital Management Inc38,993$106.5K0.00%+5,287+15.7%Added
Traphagen Investment Advisors LLC38,962$106.4K0.01%00.0%Unchanged
Delaney Dennis R38,000$103.7K0.05%00.0%Unchanged
Cambridge Investment Research Advisors, Inc.37,893$103.0K0.00%−17,364−31.4%Reduced
Carnegie Capital Asset Management, LLC36,000$98.3K0.00%−1,000−2.7%Reduced
R Squared Ltd34,533$94.3K0.04%+18,490+115.3%Added
Diversify Wealth Management, LLC40,000$94.0K0.00%00.0%Unchanged
Penbrook Management LLC33,945$92.7K0.06%+33,945New
Universal- Beteiligungs- und Servicegesellschaft mbH33,357$91.1K0.00%+20,758+164.8%Added
Gould Asset Management LLC31,735$86.6K0.02%+20,000+170.4%Added
FMR LLC31,073$84.8K0.00%−12,508−28.7%Reduced
Intrepid Family Office LLC30,000$81.9K0.08%−10,000−25.0%Reduced
Optiver Holding B.V.29,568$80.7K0.00%+28,625+3,035.5%Added
Cim Investment Mangement Inc29,423$80.3K0.02%00.0%Unchanged
Grimes & Company, Inc.29,338$80.1K0.00%−14,007−32.3%Reduced
First Manhattan Co28,998$79.2K0.00%−25,302−46.6%Reduced
DRW Securities, LLC28,558$78.0K0.01%+28,558New
Pictet Asset Management Holding SA27,122$74.0K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA26,787$73.1K0.00%−27,566−50.7%Reduced
Farallon Capital Management, L.L.C.26,000$71.0K0.00%00.0%Unchanged
Flputnam Investment Management Co25,950$70.8K0.00%+5,661+27.9%Added
Ameritas Investment Partners, Inc.25,414$69.4K0.00%+3,600+16.5%Added
Squarepoint Ops LLC25,001$68.3K0.00%−18,757−42.9%Reduced
Xponance, Inc.24,288$66.3K0.00%+3,950+19.4%Added
Wealth Enhancement Advisory Services, LLC25,150$64.1K0.00%−2,808−10.0%Reduced
Brookstone Capital Management22,683$61.9K0.00%−238−1.0%Reduced
Jump Financial, LLC22,062$60.2K0.00%+22,062New
PVG Asset Management Corp20,960$57.2K0.12%+570+2.8%Added
CIBC World Markets Corp20,344$55.5K0.00%+20,344New
One68 Global Capital, LLC20,000$55.0K0.65%+20,000New
Clearstead Advisors, LLC20,000$54.6K0.00%00.0%Unchanged
Destination Wealth Management20,000$54.6K0.00%+20,000New
Shay Capital LLC20,000$54.6K0.01%+20,000New
Adams Wealth Management19,227$52.9K0.01%00.0%Unchanged
CacheTech Inc.19,227$52.9K0.01%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.19,290$52.7K0.00%+5,301+37.9%Added
Envestnet Asset Management Inc19,209$52.4K0.00%−43,839−69.5%Reduced
HighTower Advisors, LLC19,089$52.1K0.00%+7,718+67.9%Added
Legato Capital Management LLC18,478$50.4K0.00%+1,619+9.6%Added
Sterling Capital Management LLC17,725$48.4K0.00%−292−1.6%Reduced
Prudential Financial Inc17,665$48.2K0.00%−17,165−49.3%Reduced
Public Employees Retirement Association of Colorado16,764$46.0K0.00%00.0%Unchanged
Dynamic Technology Lab Private Ltd16,872$46.0K0.01%+16,872New
Mackenzie Financial Corp16,360$45.2K0.00%−1,127−6.4%Reduced
Pathstone Holdings, LLC16,273$44.4K0.00%+16,273New
Beacon Financial Advisory LLC16,195$44.2K0.01%−4,040−20.0%Reduced
Bayesian Capital Management, LP15,300$41.8K0.10%+15,300New
Excelsior Advisor Network LLC15,150$41.4K0.02%+15,150New
Two Sigma Securities, LLC14,040$38.3K0.01%+14,040New
HBK Sorce Advisory LLC15,027$38.0K0.00%+1,199+8.7%Added
Swiss Life Asset Management Ltd13,267$36.2K0.00%+2,190+19.8%Added
RSM US Wealth Management LLC13,069$36.2K0.00%+2,978+29.5%Added
Principal Financial Group Inc13,248$36.2K0.00%−3,000,505−99.6%Reduced
Rathbone Brothers plc12,854$35.1K0.00%−300−2.3%Reduced
Jacobs Levy Equity Management, Inc12,788$34.9K0.00%+12,788New
JustInvest LLC12,637$34.5K0.00%+12,637New
XML Financial, LLC12,500$34.1K0.00%00.0%Unchanged
We Are One Seven, LLC12,458$34.0K0.00%+1,420+12.9%Added
Regions Financial Corp12,000$32.8K0.00%00.0%Unchanged
Walleye Trading LLC11,952$32.6K0.00%+11,952New
Arcadia Wealth Management, Inc.11,700$31.9K0.02%−4,050−25.7%Reduced