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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2025

Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
678
+121 vs. Q3 2025
Shares held
217.4M
+6.76M (+3.2%) vs. Q3 2025
Total value
$37.8B
+$7.55B (+24.9%) vs. Q3 2025
New holders
202
241 more added
Sold out
81
180 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 678 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ4 2025: $37.8B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.

Institutions holding INSM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Virginia Retirement Systems Et Al0$00.00%−21,265−100.0%Sold out
Fieldview Capital Management, LLC0$00.00%−20,229−100.0%Sold out
Superstring Capital Management LP0$00.00%−19,786−100.0%Sold out
Group One Trading, L.P.0$00.00%−16,535−100.0%Sold out
IMC-Chicago, LLC0$00.00%−15,282−100.0%Sold out
Granahan Investment Management Inc0$00.00%−13,402−100.0%Sold out
Dana Investment Advisors, Inc.0$00.00%−13,375−100.0%Sold out
Qsemble Capital Management, LP0$00.00%−10,711−100.0%Sold out
Park Avenue Securities LLC0$00.00%−10,677−100.0%Sold out
Neo Ivy Capital Management0$00.00%−9,688−100.0%Sold out
Wellington Shields Capital Management, LLC0$00.00%−8,472−100.0%Sold out
Lion Point Capital, LP0$00.00%−6,250−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−6,014−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−5,884−100.0%Sold out
Fox Run Management, L.L.C.0$00.00%−5,012−100.0%Sold out
Baader Bank INC0$00.00%−5,032−100.0%Sold out
Axq Capital, LP0$00.00%−4,852−100.0%Sold out
Cannon Global Investment Management, LLC0$00.00%−4,500−100.0%Sold out
Thrivent Financial for Lutherans0$00.00%−4,487−100.0%Sold out
Aigen Investment Management, LP0$00.00%−4,465−100.0%Sold out
Pitcairn Co0$00.00%−4,379−100.0%Sold out
Wellington Shields & Co., LLC0$00.00%−3,950−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−3,835−100.0%Sold out
Banque Transatlantique SA0$00.00%−3,708−100.0%Sold out
Worldquant Millennium Advisors LLC0$00.00%−3,580−100.0%Sold out
Kohlberg Kravis Roberts & Co. L.P.0$00.00%−3,284−100.0%Sold out
Beirne Wealth Consulting Services, LLC0$00.00%−3,058−100.0%Sold out
Natixis0$00.00%−3,036−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−2,918−100.0%Sold out
CTC Alternative Strategies, Ltd.0$00.00%−2,850−100.0%Sold out
Henshaw Capital LLC0$00.00%−2,832−100.0%Sold out
Headlands Technologies LLC0$00.00%−2,815−100.0%Sold out
Vivaldi Capital Management, LLC0$00.00%−2,238−100.0%Sold out
Apollon Wealth Management, LLC0$00.00%−2,050−100.0%Sold out
Jupiter Wealth Management LLC0$00.00%−2,000−100.0%Sold out
Citizens Financial Group Inc0$00.00%−1,833−100.0%Sold out
Ossiam0$00.00%−1,773−100.0%Sold out
Significant Wealth Partners LLC0$00.00%−1,740−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−1,703−100.0%Sold out
RWC Asset Management LLP0$00.00%−1,648−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−1,425−100.0%Sold out
EntryPoint Capital, LLC0$00.00%−1,421−100.0%Sold out
PharVision Advisers, LLC0$00.00%−1,404−100.0%Sold out
Venture Visionary Partners LLC0$00.00%−1,400−100.0%Sold out
Johnson Financial Group, Inc.0$00.00%−466−100.0%Sold out
Aster Capital Management (DIFC) Ltd0$00.00%−348−100.0%Sold out
Rise Advisors, LLC0$00.00%−316−100.0%Sold out
Ameriflex Group, Inc.0$00.00%−164−100.0%Sold out
B Group, Inc.0$00.00%−158−100.0%Sold out
Advisory Services Network, LLC0$00.00%−156−100.0%Sold out
Groupe la Francaise0$00.00%−100−100.0%Sold out
Wealthspire Advisors, LLC0$00.00%−58−100.0%Sold out
Marshall & Sterling Wealth Advisors Inc.0$00.00%−41−100.0%Sold out
Washington Trust Advisors, Inc.0$00.00%−33−100.0%Sold out
JPL Wealth Management, LLC0$00.00%−30−100.0%Sold out
Bellevue Asset Management, LLC0$00.00%−13−100.0%Sold out
Tortoise Investment Management, LLC0$00.00%−11−100.0%Sold out
Cloud Capital Management, LLC0$00.00%−11−100.0%Sold out
Plante Moran Financial Advisors, LLC0$00.00%−5−100.0%Sold out
AXA Investment Managers S.A.––––Not filed
Point72 (DIFC) Ltd––––Not filed
Wolverine Trading, LLC––––Not filed
EFG Asset Management (North America) Corp.––––Not filed
Point72 Asia (Singapore) Pte. Ltd.––––Not filed
Point72 Hong Kong Ltd––––Not filed
Shell Asset Management Co––––Not filed
Wetherby Asset Management Inc––––Not filed
Hemington Wealth Management––––Not filed