INSMED Inc
INSM- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001104506
In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 678
- +121 vs. Q3 2025
- Shares held
- 217.4M
- +6.76M (+3.2%) vs. Q3 2025
- Total value
- $37.8B
- +$7.55B (+24.9%) vs. Q3 2025
- New holders
- 202
- 241 more added
- Sold out
- 81
- 180 more reduced
9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 667 | $23.8B |
| Q1 2026 | 675 | $35.7B |
| Q4 2025 | 678 | $37.8B |
| Q3 2025 | 566 | $30.3B |
| Q2 2025 | 516 | $21.2B |
| Q1 2025 | 442 | $15.3B |
| Q4 2024 | 439 | $13.3B |
| Q3 2024 | 414 | $13.7B |
| Q2 2024 | 378 | $11.7B |
| Q1 2024 | 288 | $4.07B |
| Q4 2023 | 271 | $4.64B |
| Q3 2023 | 252 | $3.72B |
| Q2 2023 | 223 | $3.09B |
| Q1 2023 | 230 | $2.48B |
| Q4 2022 | 225 | $2.87B |
| Q3 2022 | 238 | $2.74B |
| Q2 2022 | 214 | $2.55B |
| Q1 2022 | 224 | $2.97B |
| Q4 2021 | 214 | $3.36B |
| Q3 2021 | 193 | $3.40B |
| Q2 2021 | 203 | $3.46B |
| Q1 2021 | 199 | $3.63B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Balyasny Asset Management LLC | 380,561 | $66.2M | 0.12% | +343,080+915.3% | Added |
| Ensign Peak Advisors, Inc | 382,202 | $66.5M | 0.12% | −259,832−40.5% | Reduced |
| Marshall Wace, LLP | 389,881 | $67.9M | 0.07% | −268,766−40.8% | Reduced |
| Two Sigma Advisers, LP | 395,000 | $68.7M | 0.13% | +343,700+670.0% | Added |
| Dimensional Fund Advisors LP | 399,073 | $69.5M | 0.01% | +12,402+3.2% | Added |
| Candriam Luxembourg S.C.A. | 401,042 | $69.8M | 0.35% | +3,454+0.9% | Added |
| Westfield Capital Management Co LP | 432,521 | $75.3M | 0.31% | −55,406−11.4% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 435,442 | $75.8M | 0.04% | +435,442 | New |
| Barclays PLC | 444,706 | $77.4M | 0.03% | +330,510+289.4% | Added |
| Affinity Asset Advisors, LLC | 450,000 | $78.3M | 5.63% | 00.0% | Unchanged |
| AQR Capital Management LLC | 468,260 | $81.5M | 0.04% | +180,974+63.0% | Added |
| GW&K Investment Management, LLC | 482,670 | $84.0M | 0.73% | −119,133−19.8% | Reduced |
| Eventide Asset Management, LLC | 483,589 | $84.2M | 1.31% | −521,518−51.9% | Reduced |
| Wellington Management Group LLP | 486,138 | $84.6M | 0.01% | −231,905−32.3% | Reduced |
| Palo Alto Investors LP | 489,482 | $85.2M | 11.86% | −2,323−0.5% | Reduced |
| TimesSquare Capital Management, LLC | 490,506 | $85.4M | 1.29% | +65,421+15.4% | Added |
| Nearwater Capital Markets, Ltd | 500,000 | $87.0M | 1.49% | +300,000+150.0% | Added |
| Royal Bank of Canada | 506,811 | $88.2M | 0.02% | −848,520−62.6% | Reduced |
| Legal & General Group Plc | 540,313 | $94.0M | 0.02% | +332,292+159.7% | Added |
| Jennison Associates LLC | 562,296 | $97.9M | 0.06% | −40,479−6.7% | Reduced |
| Swiss National Bank | 579,112 | $100.8M | 0.06% | +207,812+56.0% | Added |
| Wells Fargo & Company | 586,651 | $102.1M | 0.02% | +72,802+14.2% | Added |
| Deutsche Bank AG | 590,030 | $102.7M | 0.03% | +385,676+188.7% | Added |
| Federated Hermes, Inc. | 632,298 | $110.0M | 0.18% | +304,075+92.6% | Added |
| Hood River Capital Management LLC | 637,577 | $111.0M | 1.22% | −243,826−27.7% | Reduced |
| Alliancebernstein L.P. | 642,719 | $111.9M | 0.04% | −226,053−26.0% | Reduced |
| Victory Capital Management Inc | 646,714 | $112.6M | 0.06% | +291,807+82.2% | Added |
| Nuveen, LLC | 650,404 | $113.2M | 0.03% | +62,282+10.6% | Added |
| Artia Global Partners LP | 682,212 | $118.7M | 19.08% | −50,000−6.8% | Reduced |
| Lord, Abbett & Co. LLC | 720,898 | $125.5M | 0.38% | −723,758−50.1% | Reduced |
| Principal Financial Group Inc | 771,358 | $134.2M | 0.07% | −92,936−10.8% | Reduced |
| Raymond James Financial Inc | 779,254 | $135.6M | 0.04% | +19,276+2.5% | Added |
| Janus Henderson Group PLC | 800,555 | $139.3M | 0.06% | −402,228−33.4% | Reduced |
| Holocene Advisors, LP | 801,165 | $139.4M | 0.29% | −282,516−26.1% | Reduced |
| Clearbridge Investments, LLC | 819,011 | $142.5M | 0.11% | −249,007−23.3% | Reduced |
| FIL Ltd | 838,509 | $145.9M | 0.11% | −13,445−1.6% | Reduced |
| SEI Investments Co | 890,170 | $154.9M | 0.15% | +296,285+49.9% | Added |
| Summit Partners Public Asset Management, LLC | 909,080 | $158.2M | 4.45% | −132,765−12.7% | Reduced |
| BNP Paribas Arbitrage, SA | 915,419 | $159.3M | 0.10% | +482,079+111.2% | Added |
| Amundi | 916,998 | $159.6M | 0.04% | +599,902+189.2% | Added |
| Jefferies Financial Group Inc. | 926,339 | $161.2M | 1.32% | +818,242+757.0% | Added |
| UBS Asset Management Americas Inc | 943,306 | $164.2M | 0.03% | +430,557+84.0% | Added |
| Pictet Asset Management Holding SA | 958,963 | $167.3M | 0.16% | −181,864−15.9% | Reduced |
| Two Sigma Investments, LP | 962,156 | $167.5M | 0.25% | +189,376+24.5% | Added |
| Nwi Management LP | 988,460 | $172.0M | 10.51% | −32,540−3.2% | Reduced |
| Fiera Capital Corp | 992,892 | $172.8M | 0.55% | +183,771+22.7% | Added |
| Charles Schwab Investment Management Inc | 1,027,355 | $178.8M | 0.03% | +52,076+5.3% | Added |
| Citadel Advisors LLC | 1,157,295 | $201.4M | 0.14% | −900,346−43.8% | Reduced |
| Nomura Asset Management International Inc. | 1,183,029 | $205.9M | 0.31% | +1,183,029 | New |
| William Blair Investment Management, LLC | 1,221,096 | $212.5M | 0.59% | −333,961−21.5% | Reduced |
| Northern Trust Corp | 1,238,438 | $215.5M | 0.03% | +165,496+15.4% | Added |
| Goldman Sachs Group Inc | 1,244,913 | $216.7M | 0.03% | +415,596+50.1% | Added |
| Integral Health Asset Management, LLC | 1,250,000 | $217.6M | 11.03% | −350,000−21.9% | Reduced |
| Castle Hook Partners LP | 1,253,568 | $218.2M | 3.14% | +162,163+14.9% | Added |
| Millennium Management LLC | 1,311,654 | $228.3M | 0.16% | −1,024,458−43.9% | Reduced |
| Bank of New York Mellon Corp | 1,390,042 | $241.9M | 0.04% | +251,141+22.1% | Added |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 1,481,752 | $257.9M | 6.11% | −941,683−38.9% | Reduced |
| Morgan Stanley | 1,631,906 | $284.0M | 0.02% | +668,275+69.3% | Added |
| Bank of America Corp | 1,725,681 | $300.3M | 0.02% | +123,875+7.7% | Added |
| UBS Group AG | 1,867,635 | $325.0M | 0.06% | +221,396+13.4% | Added |
| Ameriprise Financial Inc | 1,968,857 | $342.7M | 0.08% | −753,022−27.7% | Reduced |
| Franklin Resources Inc | 2,755,536 | $479.6M | 0.12% | +615,811+28.8% | Added |
| Norges Bank | 2,910,971 | $506.6M | 0.05% | +2,910,971 | New |
| Price T Rowe Associates Inc | 4,039,466 | $703.0M | 0.08% | −2,892,000−41.7% | Reduced |
| Orbis Allan Gray Ltd | 4,179,957 | $727.5M | 3.05% | +929,089+28.6% | Added |
| Geode Capital Management, LLC | 4,299,052 | $751.9M | 0.05% | +539,625+14.4% | Added |
| D. E. Shaw & Co., Inc. | 4,350,995 | $757.2M | 0.58% | −1,306,469−23.1% | Reduced |
| RTW Investments, LP | 4,842,879 | $842.9M | 8.44% | +1,758,321+57.0% | Added |
| Artisan Partners Limited Partnership | 4,843,749 | $843.0M | 1.29% | −93,934−1.9% | Reduced |
| Capital International Investors | 5,151,671 | $896.6M | 0.14% | −2,402,182−31.8% | Reduced |
| State Street Corp | 5,201,744 | $905.3M | 0.03% | +1,217,390+30.6% | Added |
| Baker Bros. Advisors LP | 6,592,746 | $1.15B | 6.72% | −110,738−1.7% | Reduced |
| Invesco Ltd. | 7,518,338 | $1.31B | 0.12% | +5,514,467+275.2% | Added |
| FMR LLC | 9,927,936 | $1.73B | 0.09% | +746,973+8.1% | Added |
| BlackRock, Inc. | 15,065,052 | $2.62B | 0.04% | +2,700,148+21.8% | Added |
| Darwin Global Management, Ltd. | 20,933,277 | $3.64B | 73.78% | +475,832+2.3% | Added |
| Vanguard Group Inc | 21,076,344 | $3.67B | 0.05% | +1,140,524+5.7% | Added |
| JPMorgan Chase & Co | 23,199,512 | $4.04B | 0.27% | +151,836+0.7% | Added |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −1,544,315−100.0% | Sold out |
| Perceptive Advisors LLC | 0 | $0 | 0.00% | −702,130−100.0% | Sold out |
| Maverick Capital LtdSuperinvestorMaverick Capital | 0 | $0 | 0.00% | −656,539−100.0% | Sold out |
| 1832 Asset Management L.P. | 0 | $0 | 0.00% | −584,800−100.0% | Sold out |
| Alkeon Capital Management LLC | 0 | $0 | 0.00% | −500,000−100.0% | Sold out |
| Voloridge Investment Management, LLC | 0 | $0 | 0.00% | −471,649−100.0% | Sold out |
| Deerfield Management Company, L.P. (Series C) | 0 | $0 | 0.00% | −471,000−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −464,217−100.0% | Sold out |
| Brevan Howard Capital Management LP | 0 | $0 | 0.00% | −294,047−100.0% | Sold out |
| Algert Global LLC | 0 | $0 | 0.00% | −144,726−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −76,753−100.0% | Sold out |
| Aquatic Capital Management LLC | 0 | $0 | 0.00% | −76,343−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −60,635−100.0% | Sold out |
| Jain Global LLC | 0 | $0 | 0.00% | −55,938−100.0% | Sold out |
| Connor, Clark & Lunn Investment Management Ltd. | 0 | $0 | 0.00% | −51,658−100.0% | Sold out |
| Empowered Funds, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Catalyst Funds Management Pty Ltd | 0 | $0 | 0.00% | −47,900−100.0% | Sold out |
| Polymer Capital Management (HK) LTD | 0 | $0 | 0.00% | −44,416−100.0% | Sold out |
| StemPoint Capital LP | 0 | $0 | 0.00% | −43,419−100.0% | Sold out |
| Hillsdale Investment Management Inc. | 0 | $0 | 0.00% | −42,700−100.0% | Sold out |
| Quadrature Capital Ltd | 0 | $0 | 0.00% | −37,735−100.0% | Sold out |
| Quantessence Capital LLC | 0 | $0 | 0.00% | −28,157−100.0% | Sold out |