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INSMED Inc

INSM
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001104506

In the last 90 days, INSMED Inc insiders filed 0 open-market purchases and 7 sales; 667 institutions reported holding it in 13F filings for Q2 2026, worth $23.8B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2025

Institutional positions in INSMED Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
678
+121 vs. Q3 2025
Shares held
217.4M
+6.76M (+3.2%) vs. Q3 2025
Total value
$37.8B
+$7.55B (+24.9%) vs. Q3 2025
New holders
202
241 more added
Sold out
81
180 more reduced

9 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting INSM on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 678 institutions
Q1 2021: 199 institutionsQ2 2021: 203 institutionsQ3 2021: 193 institutionsQ4 2021: 214 institutionsQ1 2022: 224 institutionsQ2 2022: 214 institutionsQ3 2022: 238 institutionsQ4 2022: 225 institutionsQ1 2023: 230 institutionsQ2 2023: 223 institutionsQ3 2023: 252 institutionsQ4 2023: 271 institutionsQ1 2024: 288 institutionsQ2 2024: 378 institutionsQ3 2024: 414 institutionsQ4 2024: 439 institutionsQ1 2025: 442 institutionsQ2 2025: 516 institutionsQ3 2025: 566 institutionsQ4 2025: 678 institutionsQ1 2026: 675 institutionsQ2 2026: 667 institutions
Value heldQ4 2025: $37.8B
Q1 2021: $3.63BQ2 2021: $3.46BQ3 2021: $3.40BQ4 2021: $3.36BQ1 2022: $2.97BQ2 2022: $2.55BQ3 2022: $2.74BQ4 2022: $2.87BQ1 2023: $2.48BQ2 2023: $3.09BQ3 2023: $3.72BQ4 2023: $4.64BQ1 2024: $4.07BQ2 2024: $11.7BQ3 2024: $13.7BQ4 2024: $13.3BQ1 2025: $15.3BQ2 2025: $21.2BQ3 2025: $30.3BQ4 2025: $37.8BQ1 2026: $35.7BQ2 2026: $23.8B
Institutions holding INSM and their total value by quarter
QuarterHoldersValue
Q2 2026667$23.8B
Q1 2026675$35.7B
Q4 2025678$37.8B
Q3 2025566$30.3B
Q2 2025516$21.2B
Q1 2025442$15.3B
Q4 2024439$13.3B
Q3 2024414$13.7B
Q2 2024378$11.7B
Q1 2024288$4.07B
Q4 2023271$4.64B
Q3 2023252$3.72B
Q2 2023223$3.09B
Q1 2023230$2.48B
Q4 2022225$2.87B
Q3 2022238$2.74B
Q2 2022214$2.55B
Q1 2022224$2.97B
Q4 2021214$3.36B
Q3 2021193$3.40B
Q2 2021203$3.46B
Q1 2021199$3.63B

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding INSMED Inc; share changes are against Q3 2025.

Institutions holding INSM in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Walleye Capital LLC15,820$2.75M0.02%+8,890+128.3%Added
Allstate Corp15,870$2.76M0.04%+15,870New
Verition Fund Management LLC16,043$2.79M0.02%−12,109−43.0%Reduced
Tobam16,308$2.84M0.70%−2,789−14.6%Reduced
Amalgamated Bank16,743$2.91M0.02%+2,210+15.2%Added
Rockefeller Capital Management L.P.16,775$2.92M0.01%+7,863+88.2%Added
Harvest Fund Management Co., Ltd17,291$3.01M0.11%+14,454+509.5%Added
Nisa Investment Advisors, LLC17,542$3.05M0.01%+7,076+67.6%Added
Walleye Trading LLC17,657$3.07M0.05%−3,428−16.3%Reduced
CIBC World Markets Corp17,694$3.08M0.02%+17,694New
Avidity Partners Management LP17,700$3.08M0.89%+6,100+52.6%Added
Cinctive Capital Management LP17,945$3.12M0.18%−48,236−72.9%Reduced
Public Employees Retirement Association of Colorado19,020$3.31M0.01%00.0%Unchanged
Advisor Group Holdings, Inc.19,276$3.35M0.00%−3,472−15.3%Reduced
Cerity Partners LLC19,399$3.38M0.00%−1,962−9.2%Reduced
Quantinno Capital Management LP19,541$3.40M0.01%+6,763+52.9%Added
Silvant Capital Management LLC19,584$3.41M0.12%+19,584New
Baird Financial Group, Inc.19,684$3.43M0.01%−2,702−12.1%Reduced
Brown Advisory Inc19,989$3.48M0.00%−6,120−23.4%Reduced
Nordea Investment Management AB20,008$3.49M0.00%+20,008New
Next Century Growth Investors LLC20,301$3.53M0.25%+4,452+28.1%Added
Atria Investments LLC20,385$3.55M0.04%−1,028−4.8%Reduced
SBI Okasan Asset Management Co.Ltd.20,200$3.56M0.20%+20,200New
Storebrand Asset Management AS20,627$3.59M0.01%+20,627New
Rakuten Investment Management, Inc.20,466$3.61M0.01%+20,466New
CI Private Wealth, LLC20,865$3.63M0.00%+5,305+34.1%Added
Canada Pension Plan Investment Board21,000$3.65M0.00%−41,013−66.1%Reduced
ASR Vermogensbeheer N.V.21,108$3.67M0.04%+21,108New
Toroso Investments, LLC21,310$3.71M0.02%+10,512+97.4%Added
Sanctuary Advisors, LLC21,336$3.71M0.02%+1,802+9.2%Added
Mackenzie Financial Corp21,620$3.76M0.00%+4,801+28.5%Added
Gotham Asset Management, LLC21,762$3.79M0.01%+20,113+1,219.7%Added
EFG International AG21,869$3.81M0.07%+21,869New
Campbell & CO Investment Adviser LLC21,910$3.81M0.18%+2,850+15.0%Added
O'Shaughnessy Asset Management, LLC21,929$3.82M0.02%+8,703+65.8%Added
PEAK6 LLC22,190$3.86M0.11%+22,190New
Sumitomo Mitsui DS Asset Management Company, Ltd22,303$3.88M0.03%+22,303New
Shelton Capital Management24,319$4.23M0.08%+24,319New
OrbiMed Advisors LLC25,400$4.42M0.09%+11,941+88.7%Added
Acuta Capital Partners, LLC25,878$4.50M3.06%−12,714−32.9%Reduced
Renaissance Technologies LLC25,900$4.51M0.01%−326,987−92.7%Reduced
SummitTX Capital, L.P.25,967$4.52M0.14%+17,167+195.1%Added
McRae Capital Management Inc26,675$4.64M0.95%−520−1.9%Reduced
iA Global Asset Management Inc.26,682$4.64M0.06%+26,516+15,973.5%Added
Pathstone Holdings, LLC26,954$4.69M0.02%−4,667−14.8%Reduced
Atomi Financial Group, Inc.27,651$4.81M0.14%+3,912+16.5%Added
Profund Advisors LLC27,844$4.85M0.15%+16,471+144.8%Added
HealthInvest Partners AB27,873$4.85M1.55%+27,873New
KVP Capital Advisors, LP28,497$4.96M5.12%+28,497New
GordonMD Global Investments LP28,587$4.98M3.57%+28,587New
Caisse de Depot Et Placement du Quebec29,500$5.13M0.01%−134,900−82.1%Reduced
PensionDanmark Pensionsforsikringsaktieselskab30,295$5.27M0.05%+30,295New
Nomura Holdings Inc30,485$5.31M0.02%+30,485New
BI Asset Management Fondsmaeglerselskab A/S30,527$5.31M0.05%−6,897−18.4%Reduced
Utah Retirement Systems32,001$5.57M0.05%+1,272+4.1%Added
Kennedy Capital Management, Inc.32,049$5.58M0.12%+1,695+5.6%Added
Calamos Advisors LLC32,155$5.60M0.02%−3,060−8.7%Reduced
Teacher Retirement System of Texas33,219$5.78M0.02%−13,418−28.8%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main33,773$5.88M0.01%+33,773New
KBC Group NV34,013$5.92M0.01%+24,396+253.7%Added
MML Investors Services, LLC34,190$5.95M0.01%−6,810−16.6%Reduced
Mariner, LLC35,272$6.14M0.01%+6,403+22.2%Added
Nwam LLC38,982$6.23M0.35%−10,556−21.3%Reduced
Freestone Grove Partners LP36,200$6.30M0.05%+36,200New
Andra AP-fonden36,300$6.32M0.08%+36,300New
Toronto Dominion Bank36,306$6.32M0.01%+36,306New
Brinker Capital Investments, LLC36,586$6.37M0.05%−107−0.3%Reduced
Simplify Asset Management Inc.36,890$6.42M0.11%+17,226+87.6%Added
Natixis Advisors, L.P.37,168$6.47M0.01%−2,282−5.8%Reduced
British Columbia Investment Management Corp37,507$6.53M0.03%+37,507New
Thornburg Investment Management Inc37,971$6.61M0.08%−6,077−13.8%Reduced
Bamco Inc38,200$6.65M0.02%00.0%Unchanged
Daiwa Securities Group Inc.38,251$6.66M0.02%+34,648+961.6%Added
Cetera Investment Advisers38,443$6.69M0.01%−2,728−6.6%Reduced
HighVista Strategies LLC39,400$6.86M1.77%−10,549−21.1%Reduced
Assetmark, Inc39,732$6.91M0.01%+4,438+12.6%Added
Legato Capital Management LLC40,006$6.96M0.60%+5,174+14.9%Added
IFM Investors Pty Ltd40,165$6.99M0.06%+40,165New
DnB Asset Management AS40,918$7.12M0.02%+37,522+1,104.9%Added
GF Fund Management Co. Ltd.42,227$7.35M0.13%+37,679+828.5%Added
China Universal Asset Management Co., Ltd.42,388$7.38M0.57%+5,337+14.4%Added
Allianz Asset Management GmbH42,607$7.42M0.01%−23,476−35.5%Reduced
Xponance, Inc.43,042$7.49M0.06%+16,624+62.9%Added
Twinbeech Capital LP44,009$7.66M0.54%+44,009New
Forsta Ap-Fonden45,100$7.85M0.05%+45,100New
NEOS Investment Management LLC47,957$8.35M0.05%+43,660+1,016.1%Added
PFA Pension, Forsikringsaktieselskab48,330$8.41M0.02%+48,330New
CIBC Asset Management Inc48,463$8.43M0.02%+43,686+914.5%Added
Soleus Capital Management, L.P.48,500$8.44M0.36%+45,950+1,802.0%Added
Mutual of America Capital Management LLC49,080$8.54M0.09%−20,674−29.6%Reduced
Monashee Investment Management LLC50,000$8.70M4.90%+50,000New
Defilade Capital Management, L.P.50,000$8.70M1.18%+50,000New
Erste Asset Management GmbH49,603$8.75M0.07%+2,003+4.2%Added
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund50,500$8.79M0.07%+50,500New
OP Asset Management Ltd50,549$8.80M0.11%+50,549New
Parnassus Investments51,643$8.99M0.02%+42,916+491.8%Added
STRS Ohio52,016$9.05M0.03%+22,562+76.6%Added
Great West Life Assurance Co54,047$9.41M0.02%+7,005+14.9%Added
Engineers Gate Manager LP54,783$9.53M0.11%+42,315+339.4%Added
Picton Mahoney Asset Management57,259$9.97M0.11%+5,656+11.0%Added